Results 1 to 10 of about 245,373 (310)

Histopathologic changes in aborted placenta

Libyan International Medical University Journal, 2020
Introduction: Histopathological examination of the placenta with clinical implications helps to make the diagnosis and deduce the cause of abortion, fetal mortality, morbidity, and pregnancy complications.
A R. Guheina Ashour, Nabeia Ali Gheryani, Tunis M Meidan   +2 more
doaj   +1 more source

Thermodynamic and Kinetic Aspects of Calcium Oxalate Crystallization and Renal Lithiasis

Biomolecules
Thermodynamic factors (supersaturation of substances that form crystals) and kinetic factors (heterogeneous nucleants and crystallization inhibitors) affect the formation of crystals and stones in the urinary tract.
Jaume Dietrich, Antònia Costa-Bauza, Félix Grases   +2 more
doaj   +1 more source

Influence of Supersaturation Level on the Efficacy of Crystallization Inhibitors

Crystals
This in vitro study examined the influence of supersaturation level on the efficacy of different inhibitors in preventing the crystallization of calcium oxalate, uric acid, and cystine.
Jaume Dietrich, Bernat Isern, Felix Grases, Antonia Costa-Bauza   +3 more
doaj   +1 more source

Relationship between calcification, atherosclerosis and matrix proteins in the human aorta

Folia Histochemica et Cytobiologica, 2021
INTRODUCTION: Extracellular matrix (ECM) proteins have been associated with atherosclerotic complications, such as plaque rupture, calcification and aneurysm.
Aleksandra Kuzan, Jerzy Wisniewski, Krzysztof Maksymowicz, Magdalena Kobielarz, Andrzej Gamian, Agnieszka Chwilkowska   +5 more
doaj   +1 more source

Pharmacokinetics and Ex Vivo Activity of 7-Methylxanthine, an Inhibitor of Monosodium Urate Crystallization

Biomedicines
Background/Objectives: 7-Methylxanthine (7-MX) is a naturally occurring metabolite of caffeine and theobromine that can inhibit the crystallization of monosodium urate (MSU) and may be useful for the prevention or treatment of gout.
Miguel D. Ferrer, Jaume Dietrich, Bernat Isern, Maria del Mar Pérez-Ferrer, Joan Albertí, Félix Grases, Antònia Costa-Bauzà   +6 more
doaj   +1 more source

Mesalazine-induced nephrolitiasis and crystalluria

Urology Case Reports
Mesalazine (5-aminosalicylic acid) is an anti-inflammatory drug used for autoimmune diseases. Premature release mesalazine in the small intestine or proximal colon can increase systemic absorption.
Rafel M. Prieto, Francesca Julià, Flor A. Ordoñez, Antonia Costa-Bauzà, Andrea Cabeza, Myriam Muñoz, Felix Grases   +6 more
doaj   +1 more source

The role of sacubitril/valsartan in abnormal renal function patients combined with heart failure: a meta-analysis and systematic analysis

Renal Failure
Aims This study aimed to investigate the efficacy and safety of sacubitril/valsartan in abnormal renal function (eGFR < 60 ml/min/1.73m2) patients combined with heart failure based on randomized controlled trials (RCTs) and observational studies.Methods ...
Xinyue Yang, Jingjing Jin, Meijuan Cheng, Jinsheng Xu, Yaling Bai   +4 more
doaj   +1 more source

Comparative efficacy of sodium thiosulfate, bisphosphonates, and cinacalcet for the treatment of vascular calcification in patients with haemodialysis: a systematic review and network meta-analysis

BMC Nephrology
Background Up to now, there is no unequivocal intervention to mitigate vascular calcification (VC) in patients with hemodialysis. This network meta-analysis aimed to systematically evaluate the clinical efficacy of sodium thiosulfate, bisphosphonates ...
Lei He, Yuzhe Li, Jingjing Jin, Meijuan Cheng, Yaling Bai, Jinsheng Xu   +5 more
doaj   +1 more source

Hexasodium Fytate (SNF472 or CSL525) Inhibits Ectopic Calcification in Various Pseudoxanthoma Elasticum and Calcinosis Cutis Animal Models

Pharmaceuticals
Background/Objectives: Ectopic calcification is a pathological condition characterized by the mineralization of soft tissues due to the deposition of calcium phosphate crystals.
Miguel D. Ferrer, Maria del Mar Pérez-Ferrer, Marc Blasco, Ida Joely Jacobs, Qiaoli Li, Olivier M. Vanakker, Lisa Dangreau, Andrea López, Gianluca Malagraba, Firas Bassissi, Joan Perelló, Carolina Salcedo   +11 more
doaj   +1 more source

Study of the histomorphology of human pineal gland

National Journal of Clinical Anatomy, 2023
Introduction: Histologically, the pineal gland shows pinealocytes, glial cells, and sometimes calcific concretions. Age-related changes in these three components have been reported by various workers.
Gyanraj Singh, Sudhansu Sekhar Sethi, Sudeepa Das, Chinmayi Mohapatra   +3 more
doaj   +1 more source