Results 1 to 10 of about 242,382 (269)

Differential regulation of the water channel protein aquaporins in chondrocytes of human knee articular cartilage by aging

open access: yesScientific Reports, 2021
Knee cartilage is in an aqueous environment filled with synovial fluid consisting of water, various nutrients, and ions to maintain chondrocyte homeostasis.
Bong Soo Kyung   +5 more
doaj   +1 more source

Vitamin D Receptor Genetic Variations May Associate with the Risk of Developing Late Fracture-Related Infection in the Chinese Han Population

open access: yesJournal of Immunology Research, 2022
Variations in the vitamin D receptor (VDR) gene are related to several inflammatory disorders. However, the potential links between such alternations and the risk of developing late fracture-related infection (FRI) remain unclear. This study investigated
Xing-qi Zhao   +6 more
doaj   +1 more source

New frontiers for cartilage repair, joint preservation and prevention

open access: yesJournal of Cartilage & Joint Preservation, 2022
Damaged cartilage is seen with increasing frequency after joint trauma, alone or in combination with other joint injuries. A poor healing of injured cartilage leads to great disability and pain and could by time develop into osteoarthritis (OA).
Mats Brittberg
doaj   +1 more source

Surgical Fixation of Chondral-Only Fragments of the Knee: A Case Series With a Mean 4-Year Follow-up

open access: yesOrthopaedic Journal of Sports Medicine, 2021
Background: Chondral-only fragments of the knee have traditionally been treated with excision, with or without cartilage restoration procedures. This is because of the historical assumption that cartilage has limited ability to heal to cancellous or ...
Andrew Gudeman MD   +2 more
doaj   +1 more source

Matrix-Associated Chondroplasty: A Novel Platelet-Rich Plasma and Concentrated Nucleated Bone Marrow Cell–Enhanced Cartilage Restoration Technique

open access: yesArthroscopy Techniques, 2014
Bone marrow stimulation techniques such as microfracture for the treatment of articular cartilage defects so far solely reproduce mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm.
Matthias R. Steinwachs, M.D.   +3 more
doaj   +1 more source

Arthroscopic Treatment of Cartilage Lesions With Microfracture and BST-CarGel

open access: yesArthroscopy Techniques, 2014
Bone marrow stimulation techniques for the treatment of articular cartilage defects such as microfracture so far have solely reproduced mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm ...
Matthias R. Steinwachs, M.D.   +2 more
doaj   +1 more source

Returning to Work After Articular Cartilage Repair Intervention: A Systematic Review

open access: yesOrthopaedic Journal of Sports Medicine, 2020
Background: The process of returning to work after cartilage treatment has not been studied in depth, even though a better understanding of potential outcomes could lead to significant benefits for the general population.
Puwapong Nimkingratana MD, PhD, MRCS, FRCOST   +1 more
doaj   +1 more source

Hypoxia regulates RhoA and Wnt/β-catenin signaling in a context-dependent way to control re-differentiation of chondrocytes

open access: yesScientific Reports, 2017
Cartilage tissue is avascular and hypoxic which regulates chondrocyte phenotype via stabilization of HIFs. Here, we investigated the role of hypoxia and HIFs in regulation of Rho and canonical Wnt signaling in chondrocytes.
Ece Öztürk   +4 more
doaj   +1 more source

Repairing a critical cranial defect using WISP1-pretreated chondrocyte scaffolds

open access: yesJournal of Tissue Engineering, 2023
In cranial flat bone fractures, spontaneous bone repair will occur only when the fracture ends are in close contact. However, in cases wherein bone discontinuity is extensive, surgical interventions are often required.
Idan Carmon   +9 more
doaj   +1 more source

Cartilage Restoration Using Dehydrated Allogeneic Cartilage, Platelet-Rich Plasma, and Autologous Cartilage Mixture Sealed With Activated Autologous Serum

open access: yesArthroscopy Techniques, 2020
Articular cartilage injury is a common source of knee pain and dysfunction. Patients in whom conservative treatment fails may benefit from surgical intervention to restore function and alleviate pain.
Tracy M. Tauro, B.S., B.A.   +5 more
doaj   +1 more source

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