Results 31 to 40 of about 482,923 (307)
Journal of Cartilage & Joint Preservation, 2021 Introduction: Autologous chondrocyte implantation (ACI) has undergone several technical modifications. Objectives: To compare clinical outcomes and graft survivorship between ''first-generation'' periosteum-covered ACI (ACI-P) and ''second-generation ...
Liana Leja, MS, Tom Minas, MD, MS
doaj +1 more source
A review of the differences between normal and osteoarthritis articular cartilage in human knee and ankle joints [PDF]
, 2009 Background: Osteoarthritis (OA) is the most common joint disease yet its pathophysiology is still poorly understood. It is more prevalent in some lower limb joints than others; in particular the knee is more commonly affected than the ankle.
Beeson, Paul +2 more
core +1 more source
Journal of the American Academy of Orthopaedic Surgeons, 2013 Cartilage damaged by trauma has a limited capacity to regenerate. Current methods of managing small chondral defects include palliative treatment with arthroscopic débridement and lavage, reparative treatment with marrow-stimulation techniques (eg, microfracture), and restorative treatment, including osteochondral grafting and autologous chondrocyte ...
Rocky S, Tuan +2 more
openaire +2 more sources
Inhibition of NADPH Oxidases Prevents the Development of Osteoarthritis
Antioxidants, 2022 Increased oxidative stress in osteoarthritis (OA) cartilage mediates catabolic signal transduction leading to extracellular matrix degradation and chondrocyte apoptosis.
Jin Han +3 more
doaj +1 more source
Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease [PDF]
, 2010 Oxidative stress is proposed as an important factor in osteoarthritis (OA). To investigate the expression of the three superoxide dismutase (SOD) antioxidant enzymes in OA.
Boot-Handford, Raymond P. +9 more
core +1 more source
Journal of Osteoporosis, 2010 Aim was to investigate fracture risk (FR) according to bone loss (BL) rate. A random sample of 1652 women aged 53.5 years was measured with dual X-ray absorptiometry in femoral neck in 1989 and 1994 and divided into tertiles of annual BL rate: high >0.84%
Joonas Sirola +8 more
doaj +1 more source
Induction of WNT16 via peptide-mRNA nanoparticle-based delivery maintains cartilage homeostasis [PDF]
, 2020 Osteoarthritis (OA) is a progressive joint disease that causes significant disability and pain and for which there are limited treatment options. We posit that delivery of anabolic factors that protect and maintain cartilage homeostasis will halt or ...
Akk, Antonina +6 more
core +2 more sources
Viability of Periosteal Tissue Obtained Postmortem
Cell Transplantation, 1999 Periosteal autografts have the potential to regenerate articular cartilage defects, but this potential is limited by the patient's age. Allograft transplantation from a young donor to an older recipient might bypass this limitation.
Shawn W. O'driscoll Ph.D., M.D. +3 more
doaj +1 more source
Nocturnal Changes in Knee Cartilage Thickness in Young Healthy Adults [PDF]
, 2012 Magnetic resonance imaging (MRI) allows one to analyze cartilage physiology in vivo. Cartilage deforms during loading, but little is known about its recovery after deformation.
Eckstein, F. +2 more
core +1 more source
Engineered cartilage utilizing fetal cartilage-derived progenitor cells for cartilage repair [PDF]
Scientific Reports, 2020 AbstractThe aim of this study was to develop a fetal cartilage-derived progenitor cell (FCPC) based cartilage gel through self-assembly for cartilage repair surgery, with clinically useful properties including adhesiveness, plasticity, and continued chondrogenic remodeling after transplantation.
Do Young Park +8 more
openaire +2 more sources