Results 31 to 40 of about 353,585 (187)

The Role of Senescence-Associated Secretory Phenotype in Bone Loss

Frontiers in Cell and Developmental Biology, 2022
As the population of most nations have a large proportion of older individuals, there is an increase in the prevalence of osteoporosis. Consequently, scientists have focused their attention on the pathogenic mechanisms of osteoporosis.
Runjiu Zhu, Runjiu Zhu, Haoyang Wan, Haoyang Wan, Hong Yang, Mingrui Song, Mingrui Song, Yu Chai, Yu Chai, Bin Yu, Bin Yu   +10 more
doaj   +1 more source

Extracellular Vesicles: A Potential Biomarker for Quick Identification of Infectious Osteomyelitis

Frontiers in Cellular and Infection Microbiology, 2020
Effective management of infectious osteomyelitis relies on timely microorganism identification and appropriate antibiotic therapy. Extracellular vesicles (EVs) carry protein and genetic information accumulated rapidly in the circulation upon infection ...
Songyun Deng, Songyun Deng, Yutian Wang, Yutian Wang, Shiluan Liu, Shiluan Liu, Te Chen, Te Chen, Yanjun Hu, Guangyan Zhang, Guangyan Zhang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +14 more
doaj   +1 more source

Dynamic stiffness of articular cartilage and potential repair materials [PDF]

, 2012
Cartilage has limited potential for self repair. Therefore, articular cartilage lesions often lead to early osteoarthritis. Early clinical results of cartilage replacement procedures such as autologous matrix-induced chondrogenesis (AMIC) seem promising,
Ronken, Sarah
core   +1 more source

Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis

Journal of Cartilage & Joint Preservation
Introduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear.
Yusuf Mufti, Jared P. Sachs, Andrew S. Bi, Chloe Franzia, John Ebersole, Taylor Giordano, Brian J. Cole   +6 more
doaj   +1 more source

Early Stage Foreign Body Reaction against Biodegradable Polymer Scaffolds Affects Tissue Regeneration during the Autologous Transplantation of Tissue-Engineered Cartilage in the Canine Model

Cell Transplantation, 2012
To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with a greater firmness and a 3D structure.
Yukiyo Asawa, Tomoaki Sakamoto, Makoto Komura, Makoto Watanabe, Satoru Nishizawa, Yutaka Takazawa, Tsuyoshi Takato, Kazuto Hoshi M.D., Ph.D.   +7 more
doaj   +1 more source

NF-κB/TWIST1 Mediates Migration and Phagocytosis of Macrophages in the Mice Model of Implant-Associated Staphylococcus aureus Osteomyelitis

Frontiers in Microbiology, 2020
Staphylococcus aureus (S. aureus) infection-induced osteomyelitis is a great challenge in clinic treatment. Identification of the essential genes and biological processes that are specifically changed in mononuclear cells at an early stage of S.
Yutian Wang, Yutian Wang, Yihuang Lin, Yihuang Lin, Caiyu Cheng, Caiyu Cheng, Pengyu Chen, Pengyu Chen, Ping Zhang, Hangtian Wu, Hangtian Wu, Kaiqun Li, Kaiqun Li, Ye Deng, Ye Deng, Jikun Qian, Jikun Qian, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +20 more
doaj   +1 more source

Intermediate- to Long-Term Results of Combined Anterior Cruciate Ligament Reconstruction and Autologous Chondrocyte Implantation

Orthopaedic Journal of Sports Medicine, 2017
Background: Cartilage injury associated with anterior cruciate ligament (ACL) ruptures is common; however, relatively few reports exist on concurrent cartilage repair with ACL reconstruction.
Andrew N. Pike MD, Tim Bryant RN, Takahiro Ogura MD, Tom Minas MD   +3 more
doaj   +1 more source

A novel method of articular cartilage repair. [PDF]

, 2007
Articular cartilage repair of post-traumatic articular cartilage defects and well-defined articular cartilage pathology is challenging in clinical practice and has been the focus of investigations for many years.
Reissis, N., Reissis, Nikolaos
core  

Autologous Chondrocyte Implantation “Segmental-Sandwich” Technique for Deep Osteochondral Defects in the Knee: Clinical Outcomes and Correlation With Magnetic Resonance Imaging Findings

Orthopaedic Journal of Sports Medicine, 2019
Background: Symptomatic osteochondral defects are difficult to manage, especially in patients with deep (>8-10 mm) empty defects. The restoration of articular congruence is crucial to avoid the progression to osteoarthritis (OA). Purpose: To describe the
Takahiro Ogura MD, Gergo Merkely MD, Tim Bryant BSN, RN, Carl S. Winalski MD, Tom Minas MD, MS   +4 more
doaj   +1 more source

Cartilage proteoglycans [PDF]

Seminars in Cell & Developmental Biology, 2001
The predominant proteoglycan present in cartilage is the large chondroitin sulfate proteoglycan 'aggrecan'. Following its secretion, aggrecan self-assembles into a supramolecular structure with as many as 50 monomers bound to a filament of hyaluronan.
C B, Knudson, W, Knudson
openaire   +2 more sources