Results 21 to 30 of about 310,417 (319)

Arthroscopic Treatment of Cartilage Lesions With Microfracture and BST-CarGel

open access: yesArthroscopy Techniques, 2014
Bone marrow stimulation techniques for the treatment of articular cartilage defects such as microfracture so far have solely reproduced mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm ...
Matthias R. Steinwachs, M.D.   +2 more
doaj   +1 more source

Returning to Work After Articular Cartilage Repair Intervention: A Systematic Review

open access: yesOrthopaedic Journal of Sports Medicine, 2020
Background: The process of returning to work after cartilage treatment has not been studied in depth, even though a better understanding of potential outcomes could lead to significant benefits for the general population.
Puwapong Nimkingratana MD, PhD, MRCS, FRCOST   +1 more
doaj   +1 more source

Repairing a critical cranial defect using WISP1-pretreated chondrocyte scaffolds

open access: yesJournal of Tissue Engineering, 2023
In cranial flat bone fractures, spontaneous bone repair will occur only when the fracture ends are in close contact. However, in cases wherein bone discontinuity is extensive, surgical interventions are often required.
Idan Carmon   +9 more
doaj   +1 more source

Hypoxia regulates RhoA and Wnt/β-catenin signaling in a context-dependent way to control re-differentiation of chondrocytes

open access: yesScientific Reports, 2017
Cartilage tissue is avascular and hypoxic which regulates chondrocyte phenotype via stabilization of HIFs. Here, we investigated the role of hypoxia and HIFs in regulation of Rho and canonical Wnt signaling in chondrocytes.
Ece Öztürk   +4 more
doaj   +1 more source

Periosteum-covered ACI (ACI-P) versus collagen membrane ACI (ACI-C): A single-surgeon, large cohort analysis of clinical outcomes and graft survivorship

open access: yesJournal of Cartilage & Joint Preservation, 2021
Introduction: Autologous chondrocyte implantation (ACI) has undergone several technical modifications. Objectives: To compare clinical outcomes and graft survivorship between ''first-generation'' periosteum-covered ACI (ACI-P) and ''second-generation ...
Liana Leja, MS, Tom Minas, MD, MS
doaj   +1 more source

Cartilage Restoration Using Dehydrated Allogeneic Cartilage, Platelet-Rich Plasma, and Autologous Cartilage Mixture Sealed With Activated Autologous Serum

open access: yesArthroscopy Techniques, 2020
Articular cartilage injury is a common source of knee pain and dysfunction. Patients in whom conservative treatment fails may benefit from surgical intervention to restore function and alleviate pain.
Tracy M. Tauro, B.S., B.A.   +5 more
doaj   +1 more source

Bone Loss Rate May Interact with Other Risk Factors for Fractures among Elderly Women: A 15-Year Population-Based Study

open access: yesJournal of Osteoporosis, 2010
Aim was to investigate fracture risk (FR) according to bone loss (BL) rate. A random sample of 1652 women aged 53.5 years was measured with dual X-ray absorptiometry in femoral neck in 1989 and 1994 and divided into tertiles of annual BL rate: high >0.84%
Joonas Sirola   +8 more
doaj   +1 more source

Inhibition of NADPH Oxidases Prevents the Development of Osteoarthritis

open access: yesAntioxidants, 2022
Increased oxidative stress in osteoarthritis (OA) cartilage mediates catabolic signal transduction leading to extracellular matrix degradation and chondrocyte apoptosis.
Jin Han   +3 more
doaj   +1 more source

Viability of Periosteal Tissue Obtained Postmortem

open access: yesCell Transplantation, 1999
Periosteal autografts have the potential to regenerate articular cartilage defects, but this potential is limited by the patient's age. Allograft transplantation from a young donor to an older recipient might bypass this limitation.
Shawn W. O'driscoll Ph.D., M.D.   +3 more
doaj   +1 more source

The Role of Senescence-Associated Secretory Phenotype in Bone Loss

open access: yesFrontiers in Cell and Developmental Biology, 2022
As the population of most nations have a large proportion of older individuals, there is an increase in the prevalence of osteoporosis. Consequently, scientists have focused their attention on the pathogenic mechanisms of osteoporosis.
Runjiu Zhu   +10 more
doaj   +1 more source

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