Results 21 to 30 of about 353,585 (187)

Tenascin-C fragments are endogenous inducers of cartilage matrix degradation [PDF]

, 2011
Cartilage destruction is a hallmark of osteoarthritis (OA) and is characterized by increased protease activity resulting in the degradation of critical extracellular matrix (ECM) proteins essential for maintaining cartilage integrity.
Hermansson, M, Saralili Dipa Robertson, Wait, R, Robertson, SD, Wait, Robin, Monika Hermansson, Jonathan Jones, Philip Mitchell, Mitchell, P, Sofat, N, Nidhi Sofat, Jones, J, Robin Wait   +12 more
core   +1 more source

Cartilage Restoration Using Dehydrated Allogeneic Cartilage, Platelet-Rich Plasma, and Autologous Cartilage Mixture Sealed With Activated Autologous Serum

Arthroscopy Techniques, 2020
Articular cartilage injury is a common source of knee pain and dysfunction. Patients in whom conservative treatment fails may benefit from surgical intervention to restore function and alleviate pain.
Tracy M. Tauro, B.S., B.A., Abbott Gifford, Eric D. Haunschild, B.S., Ron Gilat, M.D., Michael C. Fu, M.D., Brian J. Cole, M.D., M.B.A.   +5 more
doaj   +1 more source

Bone Loss Rate May Interact with Other Risk Factors for Fractures among Elderly Women: A 15-Year Population-Based Study

Journal of Osteoporosis, 2010
Aim was to investigate fracture risk (FR) according to bone loss (BL) rate. A random sample of 1652 women aged 53.5 years was measured with dual X-ray absorptiometry in femoral neck in 1989 and 1994 and divided into tertiles of annual BL rate: high >0.84%
Joonas Sirola, Anna-Kaisa Koistinen, Kari Salovaara, Toni Rikkonen, Marjo Tuppurainen, Jukka S. Jurvelin, Risto Honkanen, Esko Alhava, Heikki Kröger   +8 more
doaj   +1 more source

Inhibition of NADPH Oxidases Prevents the Development of Osteoarthritis

Antioxidants, 2022
Increased oxidative stress in osteoarthritis (OA) cartilage mediates catabolic signal transduction leading to extracellular matrix degradation and chondrocyte apoptosis.
Jin Han, Donghwi Park, Ji Young Park, Seungwoo Han   +3 more
doaj   +1 more source

Viability of Periosteal Tissue Obtained Postmortem

Cell Transplantation, 1999
Periosteal autografts have the potential to regenerate articular cartilage defects, but this potential is limited by the patient's age. Allograft transplantation from a young donor to an older recipient might bypass this limitation.
Shawn W. O'driscoll Ph.D., M.D., Borna Meisami, Yasushi Miura, James S. Fitzsimmons   +3 more
doaj   +1 more source

New trends in articular cartilage repair

Journal of Experimental Orthopaedics, 2015
Damage to the articular cartilage is an important, prevalent, and unsolved clinical issue for the orthopaedic surgeon. This review summarizes innovative basic research approaches that may improve the current understanding of cartilage repair processes ...
Magali Cucchiarini, Christel Henrionnet, Didier Mainard, Astrid Pinzano, Henning Madry   +4 more
doaj   +1 more source

Mini-open Subpectoral Biceps Tenodesis Using All-Suture Anchor

Arthroscopy Techniques, 2020
The proximal biceps tendon is a common source of shoulder pain and dysfunction. When patients continue to have pain after exhaustive nonoperative treatment, the long head of the biceps tendon can be effectively treated with a tenotomy or tenodesis ...
Abbott Gifford, Tracy Tauro, B.S., B.A., Eric Haunschild, B.S., Kelechi Okoroha, M.D., Brian J. Cole, M.D., M.B.A.   +4 more
doaj   +1 more source

Knee chondral delaminations and blisters

Journal of Cartilage & Joint Preservation, 2022
: Cartilage injuries are well known to be troublesome and difficult to treat. Such injuries are partial and full thickness lesions most often easily detectable on MRI scanning.
Mats Brittberg
doaj   +1 more source

Biological Knee Reconstruction With Concomitant Autologous Chondrocyte Implantation and Meniscal Allograft Transplantation

Orthopaedic Journal of Sports Medicine, 2016
Background: Treating articular cartilage defects and meniscal deficiency is challenging. Although some short- to mid-term follow-up studies report good clinical outcomes after concurrent autologous chondrocyte implantation (ACI) and meniscal allograft ...
Takahiro Ogura MD, Tim Bryant BSN, RN, Tom Minas MD, MS   +2 more
doaj   +1 more source

Optimal conditions of collagenase treatment for isolation of articular chondrocytes from aged human tissues

Regenerative Therapy, 2017
Introduction: There are various types of cartilage, including the auricular and articular cartilages. These cartilages have different functions, and their matrix volume and density of chondrocytes may differ.
Kazumichi Yonenaga, Satoru Nishizawa, Takumi Nakagawa, Yuko Fujihara, Yukiyo Asawa, Atsuhiko Hikita, Tsuyoshi Takato, Kazuto Hoshi   +7 more
doaj   +1 more source