Results 41 to 50 of about 353,585 (187)

Improved diagnosis of tibiofemoral cartilage defects on MRI images using deep learning

open access: yesJournal of Cartilage & Joint Preservation, 2021
Introduction: MRI is the modality of choice for cartilage imaging, however, its diagnostic performance is variable. Objectives: We aimed to evaluate whether deep learning can be utilized to accurately identify cartilage defects when applied to the ...
Gergo Merkely, M.D.   +7 more
doaj   +1 more source

A New Technique for Distalization of the Tibial Tubercle That Allows Preservation of the Proximal Buttress

open access: yesOrthopaedic Journal of Sports Medicine, 2018
Background: Tibial tubercle osteotomy (TTO) is a treatment option for patients with patellofemoral instability and chondrosis. Occasionally, these patients also present with patella alta, and distalization of the tibial tubercle is desirable. Free distal
Luiz Felipe Ambra MD, PhD   +2 more
doaj   +1 more source

High efficiency transfection of embryonic limb mesenchyme with plasmid DNA using square wave pulse electroporation and sucrose buffer

open access: yesBioTechniques, 2014
Micromass cultures of primary embryonic limb mesenchyme are a valuable model system for studying cartilage formation in vitro. However, high efficiency introduction of plasmid DNA into this hard-to-transfect cell type typically results in considerable ...
Brent E. Bobick   +2 more
doaj   +1 more source

Apolipoprotein E deficiency potentiates macrophage against Staphylococcus aureus in mice with osteomyelitis via regulating cholesterol metabolism

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionStaphylococcus aureus (S. aureus) osteomyelitis causes a variety of metabolism disorders in microenvironment and cells. Defining the changes in cholesterol metabolism and identifying key factors involved in cholesterol metabolism disorders ...
Mincheng Lu   +15 more
doaj   +1 more source

How to salvage the delivery of a wrong-sided meniscal allograft: A rare case series

open access: yesJournal of Cartilage & Joint Preservation, 2021
Introduction: Although rare, tissue processing errors have occurred during meniscal transplantation. The anatomic differences between the lateral and medial menisci makes this problematic for surgeons who find themselves with an incorrectly labeled graft.
Andrew Gudeman   +3 more
doaj   +1 more source

Cellular senescence in aging and osteoarthritis: Implications for cartilage repair

open access: yesActa Orthopaedica, 2016
— It is well accepted that age is an important contributing factor to poor cartilage repair following injury, and to the development of osteoarthritis.
Wei Seong Toh   +8 more
doaj   +1 more source

Biomimetic sulphated alginate hydrogels suppress IL-1β-induced inflammatory responses in human chondrocytes [PDF]

open access: yesEuropean Cells & Materials, 2017
Loss of articular cartilage from ageing, injury or degenerative disease is commonly associated with inflammation, causing pain and accelerating degradation of the cartilage matrix.
Ø Arlov   +4 more
doaj   +1 more source

Insights of cartilage imaging in cartilage regeneration

open access: yesWorld Journal of Orthopedics
Cartilage, as a specialized connective tissue, underpins joint mobility and mechanical load distribution while exhibiting inherently limited self-repair capabilities. This comprehensive review redefines the current landscape of cartilage imaging by exploring conventional and advanced modalities used to assess both the structural and biochemical ...
Jeyaraman, Madhan   +4 more
openaire   +2 more sources

Cartilage Grafting

open access: yesSeminars in Plastic Surgery, 2019
AbstractArthritis remains a widespread and yet unsolved therapeutic dilemma. Cartilage grafting has proven to be difficult and satisfactory results are often elusive. There are several inherent difficulties. These include both chondrocyte migration and the lack of sufficient uptake of nutrients to allow for graft survival.
Nikhil, Agrawal   +3 more
openaire   +3 more sources

Vitamin D Receptor Genetic Polymorphisms Associate With a Decreased Susceptibility to Extremity Osteomyelitis Partly by Inhibiting Macrophage Apoptosis Through Inhibition of Excessive ROS Production via VDR-Bmi1 Signaling

open access: yesFrontiers in Physiology, 2022
Background: Previous studies had reported that vitamin D receptor (VDR) gene polymorphisms were related to the development of several inflammatory disorders. However, potential links between such variations and the risk of developing a bone infection and
Xing-Qi Zhao   +11 more
doaj   +1 more source

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