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Considerations on the Development of Therapeutics in Vascular Calcification [PDF]
Journal of Cardiovascular Development and DiseaseCardiovascular disease is the leading cause of death worldwide. Vascular calcification, the deposition of calcium phosphate mineral in the arterial wall, is the most significant predictor of morbidity and mortality.
Ana M. Valentin Cabrera +2 more
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Niacin inhibits vascular calcification via modulating of SIRT1/SIRT6 signaling pathway [PDF]
Cell Death DiscoveryVascular calcification (VC) is a common pathological state that often accompanies calcium-phosphorus metabolism disorder and chronic kidney diseases (CKDs).
Chao-hua Kong +11 more
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Clinicopathological Features of Anticancer Drug-induced Kidney Injury [PDF]
Zhongguo quanke yixue, 2022 Background The prevalence of anticancer drug-induced kidney injury is increasing, but related renal pathology studies are still rare. Objective To analyze the clinicopathological characteristics of patients with anticancer drug-related kidney injury ...
GENG Tonghui, LI Han, JIN Jingjing, CHENG Meijuan, ZHANG Shenglei, BAI Yaling, XU Jinsheng
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Peripheral Vascular Calcification. [PDF]
Arterioscler Thromb Vasc BiolPeripheral artery disease commonly refers to diffuse atherothrombotic disease of the arteries supplying the legs. Peripheral artery disease has been relatively understudied and has not been subject to the same intensive scrutiny and research that characterizes coronary artery disease.
Lee S, Woo J, Chen Y, Arya S, Allison M.
europepmc +3 more sources
Calcimimetics and Vascular Calcification. [PDF]
Toxins (Basel)In patients with chronic kidney disease (CKD), cardiovascular events (CVA) are the main cause of morbidity and mortality. Vascular calcification, linked to bone mineral metabolism disorders such as elevated serum phosphate, parathyroid hormone (PTH), and FGF23, well-known uremic toxins, aggravate this risk.
Chandu A +5 more
europepmc +5 more sources
BMC Cardiovascular Disorders, 2023 Objectives This study aimed to analyze the possible causes of changes in cardiac function and investigate the feasibility of clinical assessment of gastrointestinal cancer in patients with or without acute kidney injury (AKI) assessed using a non ...
Huihui Chen +13 more
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Correlation between serum level of PARP1 and vascular calcification in hemodialysis patients
Linchuang shenzangbing zazhi, 2023 Objective To explore the correlation between serum level of poly(ADP-ribose) polymerase 1 (PARP1) and vascular calcification in hemodialysis (HD) patients.
Hui Zhang +4 more
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The Thermodynamics of Medial Vascular Calcification [PDF]
Frontiers in Cell and Developmental Biology, 2021 Medial vascular calcification (MVC) is a degenerative process that involves the deposition of calcium in the arteries, with a high prevalence in chronic kidney disease (CKD), diabetes, and aging. Calcification is the process of precipitation largely of calcium phosphate, governed by the laws of thermodynamics that should be acknowledged in studies of ...
Millán, Ángel +2 more
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Pathophysiology and Clinical Impacts of Chronic Kidney Disease on Coronary Artery Calcification
Journal of Cardiovascular Development and Disease, 2023 The global prevalence of chronic kidney disease (CKD) has increased in recent years. Adverse cardiovascular events have become the main cause of life-threatening events in patients with CKD, and vascular calcification is a risk factor for cardiovascular ...
Zhuoming Dai, Xiangyu Zhang
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Frontiers in Cardiovascular Medicine, 2022 Vascular calcification is an irreversible pathological process associated with a loss of vascular wall function. This process occurs as a result of aging and age-related diseases, such as cardiovascular and chronic kidney diseases, and leads to ...
Cristina Mas-Bargues +7 more
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