Results 1 to 10 of about 66,303 (295)
Runx2 acetylation enhances pulmonary inflammation in chronic obstructive pulmonary disease through activating CDK8. [PDF]
Respir ResBackground Runt-related transcription factor 2 (Runx2), a transcription factor of the RUNX family, is involved in various inflammatory diseases. However, the role of Runx2 was unclear in chronic obstructive pulmonary disease (COPD).
Ma YC +14 more
europepmc +2 more sources
Molecular Cancer, 2012 Background The Runt-related transcription factor Runx2 is essential for bone development but is also implicated in progression of several cancers of breast, prostate and bone, where it activates cancer-related genes and promotes invasive properties.
Manish Tandon +2 more
exaly +3 more sources
Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease. [PDF]
Front Cell Dev BiolObjectiveKashin-Beck disease (KBD) is a nutrition-related osteoarthropathy characterized by excessive apoptosis and matrix destruction. Micronutrient selenium (Se) deficiency is recognized as a major environmental risk factor.
Zhang D, Li Q, Yang X, Xiong Y, Sun S.
europepmc +2 more sources
Cleidocranial dysplasia: A rare case report
Journal of Pharmacy and Bioallied Sciences, 2023 Cleidocranial dysplasia (CCD) is a rare hereditary disease of unknown etiology which was previously known as cleidocranial dysostosis. It usually follows an autosomal dominant mode of transmission with no predilection of genre or ethnic group.
Akshay A Dhobley +3 more
doaj +1 more source
Contemporary Clinical Dentistry, 2022 Background: It is known that a large number of mediators involved in osteogenesis can influence bone development and repair; however, whether these mediators could be used as markers of bone maturity has yet to be determined.
Daniel Fernando Hergemöller +6 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2023 Background: RUNX2 (Runt-related transcription factor 2) acts as a key regulator in the odontogenic differentiation of human dental pulp stem cells (hDPSCs). Moreover, the inclusion of exon 5 is important for RUNX2 function. Our previous study showed that
Yanan Zhang +4 more
doaj +1 more source
Global Medical Genetics, 2022 Sterile α motif domain-containing protein 9 (SAMD9) is a regulatory protein centrally involved in cell proliferation and apoptosis. Mapped to 7p21.2, variants in SAMD9 have been reported in
E. Scott Sills, Samuel H. Wood
doaj +1 more source
The effect of different intensities Resistance Training on expression mir-204 and transcription factors of osteogenic, Runx2 and biomechanical properties on bone in Old male Wistar rats [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2021 Purpose: Bones are largely influenced by nutrition, activity levels and lifestyle, and structural adaptations in the form and size of the bone occur by the forces of weight bearing and forces applied by the muscles.
ZAHRA HEMATI FARSANI +3 more
doaj +1 more source
Antioxidants, 2022 Oxidative stress associated with long-term glucocorticoids administration is a route through which secondary osteoporosis can be developed. The therapeutic potential of Phoenix dactilyfera L.
Samar R. Saleh +6 more
doaj +1 more source
Effect of cocoa administration during orthodontic tooth movement on RUNX2, calcium levels, and osteoclast bone-resorbing activity in rats [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2022 Context: Cocoa contains caffeine-rich methylxanthine, which promotes accelerated orthodontic tooth movement. Caffeine affects calcium ion equilibrium, causing low bone density and shortening orthodontic treatment.
Ananto Ali Alhasyimi +1 more
doaj +1 more source