Results 21 to 30 of about 41,144 (263)
Molecules, 2020 RUNX2, a master osteogenic transcript ion factor, is overexpressed in several cancer cells; in melanoma it promotes cells migration and invasion as well as neoangiogenesis.
Maria Teresa Valenti +5 more
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Runx2 rs59983488 polymorphism in class II malocclusion in the Indonesian subpopulation
Dental Journal, 2021 Background: Class II malocclusion is one of the main orthodontic issues for patients in seeking treatment. The prevalence of class II malocclusion varies in different populations.
Fadli Jazaldi +4 more
doaj +1 more source
LncRNA MYCNOS promotes prostate cancer cell proliferation by regulating the miR-466/RUNX2 axis
Journal of Biological Research - Thessaloniki, 2022 The function of lncRNA MYCNOS has only been reported in hepatocellular carcinoma. We studied the role of MYCNOS in prostate cancer (PC). In this study, MYCNOS expression in tissue samples from 64 PC patients was studied by RT-qPCR. Base pairing formed by
Guiliu Chen +3 more
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Role of RUNX2 in Breast Carcinogenesis [PDF]
International Journal of Molecular Sciences, 2015 RUNX2 is a transcription factor playing the major role in osteogenesis, but it can be involved in DNA damage response, which is crucial for cancer transformation. RUNX2 can interact with cell cycle regulators: cyclin-dependent kinases, pRB and p21Cip1 proteins, as well as the master regulator of the cell cycle, the p53 tumor suppressor.
Wysokinski, Daniel +2 more
openaire +2 more sources
Journal of Current Biomedical Reports, 2022 Mesenchymal stem cells (MSCs) are multipotent cells and able to differentiate into connective tissues such as bone, fat, cartilage, tendon, and muscle. They show to be very potent tools for tissue engineering and regenerative medicine. Several researches
Nooshin Barikrow, Amin Tabasi
doaj +1 more source
The International Journal of Biochemistry & Cell Biology, 2008 Runx2 is a key transcriptional modulator of osteoblast differentiation that plays a fundamental role in osteoblast maturation and homeostasis. Runx2-null mice despite normal skeletal patterning have no osteoblasts and consequently bone tissue. Mutations of the runx2 gene in humans cause cleidocranial dysplasia.
Ziros, P.G. +2 more
openaire +3 more sources
Cleidocranial dysplasia – A case report discussing the clinical and radiological manifestations
Journal of Marine Medical Society, 2020 Cleidocranial dysplasia (CCD) is a generalized skeletal disorder characterized by typical clinical and radiological abnormalities which include open cranial sutures and fontanelle, presence of Wormian bones, characteristic abnormalities of the clavicle ...
Vikram Singh Shekhawat +1 more
doaj +1 more source
European Journal of Oral Sciences, 2006 The Runx2 gene is a master transcription factor of bone and plays a role in all stages of bone formation. It is essential for the initial commitment of mesenchymal cells to the osteoblastic lineage and also controls the proliferation, differentiation, and maintenance of these cells.
Camilleri, S, McDonald, F
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Clinical and Experimental Hypertension, 2018 Vascular calcification such as arteriosclerosis, which is characterized by a calcification of the tunica media, is a severe complication of chronic kidney disease (CKD), contributing to the high prevalence of cardiovascular morbidity and mortality in ...
Shenglei Zhang +6 more
doaj +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2018 Objective: To understand the effects of combination treatment of pamidronate with isolated Quercus infectoria semi-purified fraction (QIsm-F) on human foetal osteoblast cell model (hFOB 1.19 cell line) through assessment of Runt related transcription ...
Abdullah Amira Raudhah +2 more
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