Results 31 to 40 of about 92,788 (258)

MGP T-138C Polymorphism (TT Genotype) is Associated with Vascular Calcification Incidence in Indonesian Regular Hemodialysis Patients

Indonesian Biomedical Journal, 2020
BACKGROUND: Vascular calcification contributes greatly to the incidence of cardiovascular disease. Previously, vascular calcification was considered as a passive process caused by the mineral deposition from the circulation.
Muhammad Hanif Wibowo, Riri Andri Muzasti, Syafrizal Nasution   +2 more
doaj   +1 more source

Calcification of Synthetic Vascular Grafts: A Systematic Review

EJVES Vascular Forum, 2023
Objective: Calcification of vascular grafts, including polyethylene terephthalate (PET) and expanded polytetrafluoroethylene (ePTFE) grafts may contribute to graft failure, but is under reported.
Anne Lejay, Bogdan Bratu, Salomé Kuntz, Nicole Neumann, Frederic Heim, Nabil Chakfé   +5 more
doaj   +1 more source

The role of sacubitril/valsartan in abnormal renal function patients combined with heart failure: a meta-analysis and systematic analysis

Renal Failure
Aims This study aimed to investigate the efficacy and safety of sacubitril/valsartan in abnormal renal function (eGFR < 60 ml/min/1.73m2) patients combined with heart failure based on randomized controlled trials (RCTs) and observational studies.Methods ...
Xinyue Yang, Jingjing Jin, Meijuan Cheng, Jinsheng Xu, Yaling Bai   +4 more
doaj   +1 more source

Lessons learnt from progressive vascular calcification in a renal transplant recipient

Indian Journal of Transplantation, 2022
Chronic kidney disease − mineral bone disorder is a common complication in patients with renal failure. Vascular calcification is the part of this clinical syndrome and progresses over the years.
Urmila Anandh, Ritesh Kumar, G Ramesh
doaj   +1 more source

Relationship between effective blood flow rate and clinical outcomes in maintenance hemodialysis patients: a single-center study

Renal Failure
The association between blood flow rate (BFR) and clinical outcomes in patients undergoing maintenance hemodialysis (MHD) is inconclusive. This retrospective study included 175 patients undergoing MHD treatment between July 2015 and March 2022, divided ...
Zhoucang Zhang, Jiarui Li, Jiaxiang Ding, Shenglei Zhang, Mei Wang, Jinsheng Xu   +5 more
doaj   +1 more source

Liver kinase B1 inhibits smooth muscle calcification via high mobility group box 1

Redox Biology, 2021
Vascular calcification is a common pathological feature of atherosclerosis, chronic kidney disease, vascular injury, and aging. Liver kinase B1 (LKB1) plays pivotal roles in cellular processes such as apoptosis, metabolism, and cell cycle regulation.
Tianran Zhang, Hongxuan Li, Changhan Ouyang, Guangqing Cao, Jiangang Gao, Jiliang Wu, Jianmin Yang, Nengwang Yu, Qing Min, Cheng Zhang, Wencheng Zhang   +10 more
doaj   +1 more source

Genetics of Vascular Calcification [PDF]

Circulation Research, 2011
### NT5E Mutations and Arterial Calcifications Hilaire et al NEJM. 2011;364:432–442. Recessive mutations in the NTE5 gene were recently described in lower-extremity vascular calcification. ENPP1 mutations were previously described in a severe disorder of vascular calcification in infancy.
openaire   +2 more sources

Comparative efficacy of sodium thiosulfate, bisphosphonates, and cinacalcet for the treatment of vascular calcification in patients with haemodialysis: a systematic review and network meta-analysis

BMC Nephrology
Background Up to now, there is no unequivocal intervention to mitigate vascular calcification (VC) in patients with hemodialysis. This network meta-analysis aimed to systematically evaluate the clinical efficacy of sodium thiosulfate, bisphosphonates ...
Lei He, Yuzhe Li, Jingjing Jin, Meijuan Cheng, Yaling Bai, Jinsheng Xu   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source