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Frontiers in Cardiovascular Medicine, 2023 BackgroundArterial stiffness and medial vascular calcification, leading to isolated systolic blood pressure (BP), are major cardiovascular risk factors in patients with chronic kidney disease (CKD) and mineral bone disorders (MBD).
Richard Larivière +9 more
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Vascular Biology, 2022 The present study aimed to assess the role of urocortin II (UII) in the process of vascular calcification in vitro by using a calcification model, to detect the changes in the mRNA and protein levels of associated markers in rat adventitial fibroblasts ...
Xusheng Zhang +5 more
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Treatment of vascular calcification [PDF]
Kidney International, 2008 A variety of potential therapies for vascular calcification, based either on the underlying biology or physical chemistry or solely on empiric observations in patients, may be effective but lack rigorous testing. Pasch et al. provide convincing evidence that sodium thiosulfate prevents medial vascular calcification in uremic rats.
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Vascular Calcification Mechanisms [PDF]
Journal of the American Society of Nephrology, 2004 Vascular calcification is highly correlated with cardiovascular disease mortality, especially in patients with ESRD or diabetes. In addition to the devastating effects of inappropriate biomineralization seen in cardiac valvulopathies, calciphylaxis, and idiopathic arterial calcification, vascular calcification is now recognized as a marker of ...
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Circulating microRNAs and vascular calcification in hemodialysis patients
Journal of International Medical Research, 2019 Objective Vascular calcification is common in chronic dialysis patients and is associated with increased morbidity and mortality. However, the role of circulating microRNAs (miRs) in vascular calcification has rarely been investigated.
Chien-Te Lee +4 more
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Role of Glycosylation in Vascular Calcification [PDF]
International Journal of Molecular Sciences, 2021 Glycosylation is an important step in post-translational protein modification. Altered glycosylation results in an abnormality that causes diseases such as malignancy and cardiovascular diseases. Recent emerging evidence highlights the importance of glycosylation in vascular calcification.
Ainun Nizar Masbuchin +2 more
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Journal of Renal Care, 2009 Patients with chronic kidney disease have increased cardiovascular mortality from a combination of increased atherosclerotic disease, left ventricular hypertrophy and increased prevalence of vascular calcification (VC). Previously VC was thought to be a passive process which involved the deposition of calcium and phosphate into the vessel wall. However,
Sinha, Smeeta +2 more
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Renal Replacement Therapy, 2017 Vascular calcification has now been recognized as a major problem in dialysis patients because of its strong influence on the prognosis. Along with the regulatory failure of calcification-inhibitory system, active phenotypic change of vascular smooth ...
Takayasu Ohtake, Shuzo Kobayashi
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Mechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4 [PDF]
Endocrinology and Metabolism, 2016 Vascular calcification, abnormal mineralization of the vessel wall, is frequently associated with aging, atherosclerosis, diabetes mellitus, and chronic kidney disease.
Jaechan Leem, In-Kyu Lee
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Biomedicines, 2023 Background: Vascular calcification during aging is highly prevalent in patients with cardiovascular disease; however, there is still no improvement in clarifying the development of vascular calcification.
Sisi Shao +6 more
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