Results 11 to 20 of about 841,486 (293)

Treatment of vascular calcification [PDF]

Kidney International, 2008
A variety of potential therapies for vascular calcification, based either on the underlying biology or physical chemistry or solely on empiric observations in patients, may be effective but lack rigorous testing. Pasch et al.
O'Neill, W. Charles
core   +3 more sources

Considerations on the Development of Therapeutics in Vascular Calcification

Journal of Cardiovascular Development and Disease
Cardiovascular disease is the leading cause of death worldwide. Vascular calcification, the deposition of calcium phosphate mineral in the arterial wall, is the most significant predictor of morbidity and mortality.
Ana M. Valentin Cabrera, Sophie K. Ashbrook, Joshua D. Hutcheson   +2 more
doaj   +2 more sources

Sinomenine attenuates uremia vascular calcification by miR-143-5p

Scientific Reports
Vascular calcification is considered to be a killer of the cardiovascular system, involved inflammation and immunity. There is no approved therapeutic strategy for the prevention of vascular calcification.
Fengyi Yu, Zhong Peng, Ning Gao, Zixu Tang, Zihao Liao, Song Zhao, Shuzhu Zhong, Gloria Umwiza, Hong Huang, Wei Long, Zhangxiu He   +10 more
doaj   +2 more sources

Vascular Calcification: Current Genetics Underlying This Complex Phenomenon

Chinese Medical Journal, 2017
Objective: Vascular calcification is the consequence of the complex interaction between genetic, environmental, and vascular factors, which ultimately lead to the deposition of calcium in the tunica intima (atherosclerotic calcification) or tunica media (
Nonanzit Pérez-Hernández, Gad Aptilon-Duque, Ruben Blachman-Braun, Gilberto Vargas-Alarcón, Adrián Asael Rodríguez-Cortés, Shely Azrad-Daniel, Rosalinda Posadas-Sánchez, José Manuel Rodríguez-Pérez   +7 more
doaj   +2 more sources

Calcification of Synthetic Vascular Grafts: A Systematic Review

EJVES Vascular Forum, 2023
Objective: Calcification of vascular grafts, including polyethylene terephthalate (PET) and expanded polytetrafluoroethylene (ePTFE) grafts may contribute to graft failure, but is under reported.
Anne Lejay, Bogdan Bratu, Salomé Kuntz, Nicole Neumann, Frederic Heim, Nabil Chakfé   +5 more
doaj   +2 more sources

Shifting osteogenesis in vascular calcification [PDF]

JCI Insight, 2021
Transitions between cell fates commonly occur in development and disease. However, reversing an unwanted cell transition in order to treat disease remains an unexplored area.
Jiayi Yao, Xiuju Wu, Xiaojing Qiao, Daoqin Zhang, Li Zhang, Jocelyn A. Ma, Xinjiang Cai, Kristina I. Boström, Yucheng Yao   +8 more
doaj   +2 more sources

Calcimimetics and Vascular Calcification. [PDF]

Toxins (Basel)
In patients with chronic kidney disease (CKD), cardiovascular events (CVA) are the main cause of morbidity and mortality. Vascular calcification, linked to bone mineral metabolism disorders such as elevated serum phosphate, parathyroid hormone (PTH), and
Chandu A, Arana C, Díaz-García JD, Cozzolino M, Ciceri P, Torregrosa JV.   +5 more
europepmc   +6 more sources

Vascular calcification: the role of microRNAs

Biomolecular Concepts, 2017
Vascular calcification represents the deposition of calcium phosphate salts in the tunica media of the vascular wall. It occurs during aging but is accelerated and pronounced in patients with diabetes mellitus, chronic kidney disease (CKD) and ...
Alkagiet Stelina, Tziomalos Konstantinos
doaj   +2 more sources

Renal osteodystrophy and vascular calcification

Journal of endocrinological investigation, 2009
Chronic kidney disease (CKD) is characterized by phosphate retention and reduced synthesis of 1.25(OH)2-vitamin D stimulating parathyroid hyperplasia. These changes cause a complex osteopathy, defined as renal osteodystrophy, and vascular calcification ...
V. Paloschi, T. Arcidiacono, G. Vezzoli, A. Aloia, L. Soldati, F. Rainone, E. Dogliotti, A. Terranegra   +7 more
core   +5 more sources

Vascular calcification

, 2018
Vascular calcification (VC) is a common feature of patients with advanced CKD and it could be, at least in part, the cause of increased cardiovascular mortality in these patients.
Luminita Voroneanu, Mugurel Apetrii, David J. Goldsmith, Adrian Covic   +3 more
core   +4 more sources