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Epidemiological Research Advances in Vascular Calcification in Diabetes
Vascular calcification is the transformation of arterial wall mesenchymal cells, particularly smooth muscle cells (SMCs), into osteoblast phenotypes by various pathological factors.
Haipeng Yao +6 more
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Osteoporosis and vascular calcifications
In post-menopausal women, aged individuals, and patients with diabetes mellitus or chronic renal disease, bone mineral density (BMD) decreases while the vasculature accumulates arterial calcifications (ACs). AC can be found in the tunica intima and/or in the tunica media.
Nancy Martini +2 more
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The role of mitochondria in vascular calcification [PDF]
Abstract Vascular calcification (VC) was defined as the ectopic deposition of calcium–phosphorus complexes on the blood vessel walls. It was a process involving multiple factors and mechanisms, covering the phenotype transition of vascular smooth muscle cells (VSMCs) and release of microvesicles.
Wang, Pengbo +5 more
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Vascular calcification is common in chronic kidney disease (CKD) and contributes to cardiovascular disease (CVD) without any effective therapies available up to date.
Wanbing He +7 more
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Increasing evidence suggests that aldosterone (Aldo) plays an essential role in vascular calcification which is a serious threat to cardiovascular disease (CVD) developed from chronic kidney disease (CKD).
Xueying Chang +5 more
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Macrovascular calcification increasingly afflicts our aging and dysmetabolic population.1 Once considered only a passive process of dead and dying cells, data from multiple laboratories worldwide have converged to reveal that vascular calcification is in great part an actively regulated form of matrix mineral metabolism.2 A uniquely horrendous ...
Jason C, Kovacic, Gwendalyn J, Randolph
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Vascular calcification is prevalent in aging, diabetes, chronic kidney disease, cardiovascular disease, and certain genetic disorders. However, the pathogenesis of vascular calcification is not well-understood.
Yun-Yun Wu +18 more
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Advances in CT Techniques in Vascular Calcification
Vascular calcification, a common pathological phenomenon in atherosclerosis, diabetes, hypertension, and other diseases, increases the incidence and mortality of cardiovascular diseases.
Lijie Zhang +5 more
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Clinically, vascular calcification is now accepted as a valuable predictor of coronary heart disease.151 Achieving control over this process requires understanding mechanisms in the context of a tightly-controlled regulatory network, with multiple, nested feedback loops and cross-talk between organ systems, in the realm of control theory.
Linda L, Demer, Yin, Tintut
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Multiple functions of autophagy in vascular calcification
Background Vascular calcification is a closely linked to cardiovascular diseases, such as atherosclerosis, chronic kidney disease, diabetes, hypertension and aging.
Xin Zhou +13 more
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