Results 41 to 50 of about 841,486 (293)

Mechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4 [PDF]

Endocrinology and Metabolism, 2016
Vascular calcification, abnormal mineralization of the vessel wall, is frequently associated with aging, atherosclerosis, diabetes mellitus, and chronic kidney disease.
Jaechan Leem, In-Kyu Lee
doaj   +1 more source

Influence of FOSL1 Inhibition on Vascular Calcification and ROS Generation through Ferroptosis via P53-SLC7A11 Axis

Biomedicines, 2023
Background: Vascular calcification during aging is highly prevalent in patients with cardiovascular disease; however, there is still no improvement in clarifying the development of vascular calcification.
Sisi Shao, Yaoxin Liu, Wanzi Hong, Yuanxi Mo, Fen Shu, Lei Jiang, Ning Tan   +6 more
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Role of Glycosylation in Vascular Calcification

, 2021
Glycosylation is an important step in post-translational protein modification. Altered glycosylation results in an abnormality that causes diseases such as malignancy and cardiovascular diseases.
Ping-Yen Liu, Ainun Nizar Masbuchin, Mohammad Saifur Rohman   +2 more
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Impact of vascular calcification on cardiovascular mortality in hemodialysis patients: clinical significance, mechanisms and possible strategies for treatment

Renal Replacement Therapy, 2017
Vascular calcification has now been recognized as a major problem in dialysis patients because of its strong influence on the prognosis. Along with the regulatory failure of calcification-inhibitory system, active phenotypic change of vascular smooth ...
Takayasu Ohtake, Shuzo Kobayashi
doaj   +1 more source

Lessons learnt from progressive vascular calcification in a renal transplant recipient

Indian Journal of Transplantation, 2022
Chronic kidney disease − mineral bone disorder is a common complication in patients with renal failure. Vascular calcification is the part of this clinical syndrome and progresses over the years.
Urmila Anandh, Ritesh Kumar, G Ramesh
doaj   +1 more source

The role of sacubitril/valsartan in abnormal renal function patients combined with heart failure: a meta-analysis and systematic analysis

Renal Failure
Aims This study aimed to investigate the efficacy and safety of sacubitril/valsartan in abnormal renal function (eGFR < 60 ml/min/1.73m2) patients combined with heart failure based on randomized controlled trials (RCTs) and observational studies.Methods ...
Xinyue Yang, Jingjing Jin, Meijuan Cheng, Jinsheng Xu, Yaling Bai   +4 more
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Relationship between effective blood flow rate and clinical outcomes in maintenance hemodialysis patients: a single-center study

Renal Failure
The association between blood flow rate (BFR) and clinical outcomes in patients undergoing maintenance hemodialysis (MHD) is inconclusive. This retrospective study included 175 patients undergoing MHD treatment between July 2015 and March 2022, divided ...
Zhoucang Zhang, Jiarui Li, Jiaxiang Ding, Shenglei Zhang, Mei Wang, Jinsheng Xu   +5 more
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Liver kinase B1 inhibits smooth muscle calcification via high mobility group box 1

Redox Biology, 2021
Vascular calcification is a common pathological feature of atherosclerosis, chronic kidney disease, vascular injury, and aging. Liver kinase B1 (LKB1) plays pivotal roles in cellular processes such as apoptosis, metabolism, and cell cycle regulation.
Tianran Zhang, Hongxuan Li, Changhan Ouyang, Guangqing Cao, Jiangang Gao, Jiliang Wu, Jianmin Yang, Nengwang Yu, Qing Min, Cheng Zhang, Wencheng Zhang   +10 more
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Comparative efficacy of sodium thiosulfate, bisphosphonates, and cinacalcet for the treatment of vascular calcification in patients with haemodialysis: a systematic review and network meta-analysis

BMC Nephrology
Background Up to now, there is no unequivocal intervention to mitigate vascular calcification (VC) in patients with hemodialysis. This network meta-analysis aimed to systematically evaluate the clinical efficacy of sodium thiosulfate, bisphosphonates ...
Lei He, Yuzhe Li, Jingjing Jin, Meijuan Cheng, Yaling Bai, Jinsheng Xu   +5 more
doaj   +1 more source

Genetics of Vascular Calcification [PDF]

Circulation Research, 2011
### NT5E Mutations and Arterial Calcifications Hilaire et al NEJM. 2011;364:432–442. Recessive mutations in the NTE5 gene were recently described in lower-extremity vascular calcification. ENPP1 mutations were previously described in a severe disorder of vascular calcification in infancy.
openaire   +2 more sources