Results 41 to 50 of about 807,608 (297)

Uremic Toxins and Vascular Calcification-Missing the Forest for All the Trees

, 2020
The cardiorenal syndrome relates to the detrimental interplay between the vascular system and the kidney. The uremic milieu induced by reduced kidney function alters the phenotype of vascular smooth muscle cells (VSMC) and promotes vascular calcification,
Leon Schurgers, Stenvinkel, Peter, Peter Stenvinkel, Schurgers, Leon; id_orcid, Rapp, Nikolas, Schurgers, Leon, Pieter Evenepoel, Evenepoel, Pieter, Nikolas Rapp   +8 more
core   +1 more source

Relationship between effective blood flow rate and clinical outcomes in maintenance hemodialysis patients: a single-center study

Renal Failure
The association between blood flow rate (BFR) and clinical outcomes in patients undergoing maintenance hemodialysis (MHD) is inconclusive. This retrospective study included 175 patients undergoing MHD treatment between July 2015 and March 2022, divided ...
Zhoucang Zhang, Jiarui Li, Jiaxiang Ding, Shenglei Zhang, Mei Wang, Jinsheng Xu   +5 more
doaj   +1 more source

Liver kinase B1 inhibits smooth muscle calcification via high mobility group box 1

Redox Biology, 2021
Vascular calcification is a common pathological feature of atherosclerosis, chronic kidney disease, vascular injury, and aging. Liver kinase B1 (LKB1) plays pivotal roles in cellular processes such as apoptosis, metabolism, and cell cycle regulation.
Tianran Zhang, Hongxuan Li, Changhan Ouyang, Guangqing Cao, Jiangang Gao, Jiliang Wu, Jianmin Yang, Nengwang Yu, Qing Min, Cheng Zhang, Wencheng Zhang   +10 more
doaj   +1 more source

Comparative efficacy of sodium thiosulfate, bisphosphonates, and cinacalcet for the treatment of vascular calcification in patients with haemodialysis: a systematic review and network meta-analysis

BMC Nephrology
Background Up to now, there is no unequivocal intervention to mitigate vascular calcification (VC) in patients with hemodialysis. This network meta-analysis aimed to systematically evaluate the clinical efficacy of sodium thiosulfate, bisphosphonates ...
Lei He, Yuzhe Li, Jingjing Jin, Meijuan Cheng, Yaling Bai, Jinsheng Xu   +5 more
doaj   +1 more source

Low Muscle Mass in Patients Receiving Hemodialysis: Correlations with Vascular Calcification and Vascular Access Failure

, 2021
Background: Sarcopenia involves an age-related decline in skeletal muscle mass with functional disability or low muscle strength. Vascular calcification (VC) occurs commonly in patients with chronic kidney disease, in whom it is associated with ...
Gwangho Choi, Youngjin Song, Hae Min Jeong, Miyeun Han, Jeong-Ju Yoo, Jong-woo Yoon, Seok-hyung Kim, Hyunsuk Kim, Jongho Heo, Hojung Yoon, Jae Eon Gu   +10 more
core   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Role of Vascular Smooth Muscle Cell Phenotypic Switching and Calcification in Aortic Aneurysm Formation Involvement of Vitamin K-Dependent Processes [PDF]

, 2019
Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood vessel degenerates, leading to dilation and eventually vessel wall rupture.
Petsophonsakul, Ploingarm, Schurink, Geert Willem, Natour, Ehsan, Jacobs, Michael, Schurgers, Leon; id_orcid, Mees, Barend, Schurgers, Leon, Forsythe, Rachael, Reutelingsperger, Chris, Furmanik, Malgorzata, Dweck, Marc   +10 more
core   +2 more sources

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Treatment of vascular calcification [PDF]

Kidney International, 2008
A variety of potential therapies for vascular calcification, based either on the underlying biology or physical chemistry or solely on empiric observations in patients, may be effective but lack rigorous testing. Pasch et al. provide convincing evidence that sodium thiosulfate prevents medial vascular calcification in uremic rats.
openaire   +2 more sources

Socioeconomic Status and Subclinical Coronary Disease in the Whitehall II Epidemiological Study [PDF]

, 2010
Background: There are pronounced socioeconomic disparities in coronary heart disease, but the extent to which these primarily reflect gradients in underlying coronary artery disease severity or in the clinical manifestation of advanced disease is ...
Andrew Steptoe, Katie O'Donnell, Mark Hamer, Hamer, M, Lahiri, A, Steptoe, A, Marmot, MG, O'Donnell, K, Michael G Marmot, Venuraju, S, Avijit Lahiri, Michael G. Marmot, Shreenidhi Venuraju   +12 more
core   +1 more source