Results 61 to 70 of about 807,608 (297)
Sinomenine attenuates uremia vascular calcification by miR-143-5p
Scientific ReportsVascular calcification is considered to be a killer of the cardiovascular system, involved inflammation and immunity. There is no approved therapeutic strategy for the prevention of vascular calcification.
Fengyi Yu +10 more
doaj +1 more source
Linchuang shenzangbing zazhi, 2022 ObjectiveTo explore the relationship between serum levels of miR-129 and miR-205 and vascular calcification in non-dialysis patients with chronic kidney disease （CKD）.MethodsFrom June 2020 to January 2021，54 CKD inpatients were selected as research ...
He Lei +7 more
doaj
Pharmacological and Nutritional Modulation of Vascular Calcification
, 2019 Vascular calcification is an independent predictor of cardiovascular disease, and therefore, inhibition or regression of this processes is of clinical importance.
Kroon, Abraham A.; id_orcid +9 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Vitamin K and vascular calcifications
Acta Physiologica Hungarica, 2010 The role of vitamin K in the synthesis of some coagulation factors is well known. The implication of vitamin K in vascular health was demonstrated in many surveys and studies conducted over the past years on the vitamin K-dependent proteins non-involved in coagulation processes.
Fodor, D. +3 more
openaire +4 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
, 2021 This chapter focuses on the calcification of heart valves. The extent of valve calcification may vary from mild sclerosis with no effects on valve function to the development of leaflets calcification which causes valve dysfunction. It is well known that
Koulaouzidis, George, +5 more
core +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Vascular Calcification: Current Genetics Underlying This Complex Phenomenon
Chinese Medical Journal, 2017 Objective: Vascular calcification is the consequence of the complex interaction between genetic, environmental, and vascular factors, which ultimately lead to the deposition of calcium in the tunica intima (atherosclerotic calcification) or tunica media (
Nonanzit Pérez-Hernández +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source