Results 1 to 10 of about 236,010 (265)

Production of Endothelin by Vascular Smooth Muscle Cells

Journal of Cardiovascular Pharmacology, 1991
Endothelin (ET) production by cultured vascular smooth muscle cells isolated from rat and rabbit aortae was measured by a specific radioimmunoassay. Vascular smooth muscle cells released ET at a rate of 0.6 (range of 0.1-1) fmol/10(5) cells/24 h compared to 45 (range of 10-80) fmol/10(5) cells/h for endothelial cells.
S M, Kanse, K, Takahashi, J B, Warren, T, Perera, M, Porta, M, Ghatei, S R, Bloom   +6 more
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Vascular Smooth Muscle Cells

2002
Smooth muscle is present in one form or another in most organs, and its contractile activity is vital for normal functioning of the body. To be able to perform the multitude of tasks required of the organs, smooth muscle cells vary widely in their patterns of activity.
Campbell, G. R., Efendy, J., Campbell, J. H.   +2 more
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Endothelin degradation by vascular smooth muscle cells

Regulatory Peptides, 1996
The mechanism(s) of degradation of the potent vasoconstrictor endothelin-1 (ET-1) by rat vascular smooth muscle A-10 cells, which possess the ETA receptor subtype, was investigated by incubating [125I]ET-1 (0.1 nM) with cells for 0-4 h at 37 degrees C in the presence and absence of lysosomal enzyme inhibitors, NH4Cl and chloroquine, and a neutral ...
H, Bermek, K C, Peng, K, Angelova, A, Ergul, D, Puett   +4 more
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Vascular smooth muscle cells

2017
Abstract To understand the function of arteries in the regulation of blood supply throughout the body it is essential to realize that the vessel wall is composed predominantly of smooth muscle cells (SMCs) with only one single layer of luminal endothelial cells.
Piallat, Marie-Luce, de Vries, Carlie JM, van Eys, Guillaume J   +2 more
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Pathophysiological Role of the Vascular Smooth Muscle Cell

Journal of Cardiovascular Pharmacology, 1990
The vascular smooth muscle cell of the arterial media plays a predominant role in functional and structural alterations of the arterial wall in pathophysiological processes such as arterial hypertension, atheroma, or normal aging. The observed alterations are related to the three activities of the vascular smooth muscle cell, namely contractility ...
J B, Michel, N, De Roux, D, Plissonnier, S, Anidjar, J L, Salzmann, B, Levy   +5 more
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Apoptosis of vascular smooth muscle cells in atherosclerosis

Atherosclerosis, 1998
Apoptosis (programmed cell death) of vascular smooth muscle cells and macrophages has recently been demonstrated in the following: (a) human atherosclerotic plaques; (b) physiological remodelling of the vessel; and (c) a variety of disease states. Apoptosis is a highly regulated mechanism of death, controlled by the interactions between the following: (
M R, Bennett, J J, Boyle
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Smooth Muscle Progenitor Cells in Vascular Disease

Trends in Cardiovascular Medicine, 2004
Vascular smooth muscle cells have long been described as phenotypically diverse, with some populations possessing the potential for monoclonal expansion within the adult vessel wall. Recent experimental and human data suggest a potential role in atherosclerotic plaque, transplant arteriopathy, and angiogenesis biology for putative smooth muscle ...
Chunsheng, Liu, Karl A, Nath, Zvonimir S, Katusic, Noel M, Caplice   +3 more
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Sodium Cotransport in Vascular Smooth Muscle Cells

Blood Vessels, 2008
Vascular smooth muscle cells possess a number of Na cotransport systems. Three of these cotransport systems, Na/Ca exchange, Na/H exchange and Na-K-Cl cotransport, have been the subject of an increasing number of investigations to determine the respective roles of these transporters in vascular smooth muscle cell function.
M E, O'Donnell, N E, Owen
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Vascular smooth muscle cells and calcification in atherosclerosis

American Heart Journal, 2004
Vascular calcification is a prominent feature of atherosclerosis but the mechanisms underlying vascular calcification are still obscure. Since bone-associated proteins such as osteonectin, osteocalcin, and matrix Gla protein have been detected in calcified vascular tissues, calcification has been considered to be an organized, regulated process similar
Astrid, Trion, Arnoud, van der Laarse
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The roles of autophagy in vascular smooth muscle cells

International Journal of Cardiology, 2016
Autophagy, which is an evolutionarily conserved mechanism and links to several cellular pathways, impacts vascular smooth muscle cells (VSMCs) survival and function. Activation of autophagy by intercellular and/or extracellular stimuli has protective effects on VSMCs against cell death, while on the contrary, overloading autophagy has been recognized ...
Shi, Tai, Xin-Qun, Hu, Dao-Quan, Peng, Sheng-Hua, Zhou, Xi-Long, Zheng   +4 more
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