Results 31 to 40 of about 6,256,490 (293)

Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching [PDF]

, 2012
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
DI LAURO M. V., Maria Vittoria Di Lauro (127364), Teresa Iuvone (127378), Angelo Guglielmotti, Angelo Guglielmotti (127381), Pasquale Maffia (127384), Gianluca Grassia (127362), Cicala, C., MADDALUNO, MARCELLA, Francesco Maione, Maria Vittoria Di Lauro, Nicola Mascolo, Nicola Mascolo (127387), Maffia, P., Gianluca Grassia, Armando Ialenti, Antonio Parisi (127365), GRASSIA, GIANLUCA, Guglielmotti, A., IALENTI, ARMANDO, Grassia, G., IUVONE, TERESA, MASCOLO, NICOLA DOMENICO C. FERDINANDO, Carla Cicala (127370), Pasquale Maffia, MAIONE, FRANCESCO, Maione, F., Iuvone, T., Maddaluno, M., GUGLIELMOTTI A., Daniele De Filippis (127374), De Filippis, D., Antonio Parisi, Carla Cicala, Armando Ialenti (127390), Ialenti, A., Parisi, A., CICALA, CARLA, MAFFIA, PASQUALE, Marcella Maddaluno (127360), Marcella Maddaluno, Teresa Iuvone, PARISI A., Mascolo, N., Francesco Maione (127366), Di Lauro, M.V., Daniele De Filippis, DE FILIPPIS, DANIELE   +47 more
core   +1 more source

Highly effective non-viral gene transfer into vascular smooth muscle cells of cultured resistance arteries demonstrated by genetic inhibition of sphingosine-1-phosphate-induced vasoconstriction [PDF]

, 2003
The linkage of vascular genes to specific functions will lead to a better understanding of cardiovascular pathophysiology. We developed an experimental model that enables the introduction of one or multiple gene(s) into vascular smooth muscle cells ...
Pohl, U., Bolz, S. S.
core   +2 more sources

Notch signaling pathway in human vascular smooth muscle cell differentiation [PDF]

, 2006
Notch receptor-ligand interactions are a highly conserved mechanism, originally described in developmental studies using Drosophilae, that regulate inter-cell communication and dictate, in part, vascular smooth muscle cell (VSMC) fate in response to ...
Scheller, Agnieszka
core   +2 more sources

Vascular smooth muscle cell senescence in atherosclerosis [PDF]

Cardiovascular Research, 2006
Markers of cell senescence have been identified in both the blood and vessel wall of patients with atherosclerosis. In particular, vascular smooth muscle cells (VSMCs) derived from human plaques show numerous features of senescence both in culture and in vivo.
Isabelle, Gorenne, Mary, Kavurma, Stephen, Scott, Martin, Bennett   +3 more
openaire   +2 more sources

Quantitative Analysis of Intracellular Ca2+ Release and Contraction in hiPSC-Derived Vascular Smooth Muscle Cells

Stem Cell Reports, 2019
Summary: Vascular smooth muscle cells (vSMCs) are highly heterogeneous across different vascular beds. This is partly dictated by their developmental origin but also their position in the vascular tree, reflected in their differential responses to ...
Oleh V. Halaidych, Amy Cochrane, Francijna E. van den Hil, Christine L. Mummery, Valeria V. Orlova   +4 more
doaj   +1 more source

Replication of smooth muscle cells in vascular disease. [PDF]

Circulation Research, 1986
Smooth muscle proliferation has been recognized as central to the pathology of both major forms of vascular disease: atherosclerosis and hypertension. Recent advances in our knowledge of mechanisms of control of proliferation suggest that events occurring in adult animals may recapitulate portions of the developmental biology of the smooth muscle cell.
Schwartz, SM, Campbell, GR, Campbell, JH
openaire   +4 more sources

Vascular smooth muscle cell differentiation – 2010 [PDF]

Journal of Biomedical Research, 2010
Vascular smooth muscle cells have attracted considerable interest as a model for a flexible program of gene expression. This cell type arises throughout the embryo body plan via poorly understood signaling cascades that direct the expression of transcription factors and microRNAs which, in turn, orchestrate the activation of contractile genes ...
openaire   +2 more sources

Cell cultures of human ciliary muscle: growth, ultrastructural and immunocytochemical characteristics [PDF]

, 1991
Primary ciliary muscle cell cultures derived from human donors (16-91 years) were established and characterized by comparing them with ciliary muscle in tissue sections using immunocytochemical and ultrastructural methods.
Baur, A., Tamm, Ernst R., Flügel, C., Lütjen-Drecoll, E.   +3 more
core   +1 more source

Quantification of alignment of vascular smooth muscle cells [PDF]

Cytometry Part A, 2018
AbstractVascular smooth muscle cells (VSMCs) are essential components that keep the tonus of the arterial network, which is the channel used to conduct the blood from the heart to the peripheral areas of the body. It is known that mechanical and architectural changes in VSMCs may lead to functional modifications in the cardiovascular system; therefore,
Marcel P, Dorta, Isis V, de Brito, Alexandre C, Pereira, Adriano M, Alencar   +3 more
openaire   +2 more sources

Mebendazole reduces vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice.

PLoS ONE, 2014
Mebendazole is an antihelminthic drug that exerts its effects via interference with microtubule function in parasites. To determine the utility of mebendazole as a potential treatment for vascular diseases involving proliferation of vascular smooth ...
Jintao Wang, Hui Wang, Chiao Guo, Wei Luo, Alyssa Lawler, Aswin Reddy, Julia Wang, Eddy B Sun, Daniel T Eitzman   +8 more
doaj   +1 more source