Results 11 to 20 of about 236,010 (265)

Potassium channels in vascular smooth muscle cells. [PDF]

Physiol Rev
Vascular smooth muscle cells express several types of potassium (K + ) channels that control physiological functions including contractility, migration, proliferation, and differentiation.
Garrud TAC, Collier DM, Jaggar JH.
europepmc   +4 more sources

Metabolism of vascular smooth muscle cells in vascular diseases [PDF]

American Journal of Physiology - Heart and Circulatory Physiology, 2020
Vascular smooth muscle cells (VSMCs) are the fundamental component of the medial layer of arteries and are essential for arterial physiology and pathology. It is becoming increasingly clear that VSMCs can alter their metabolism to fulfill the bioenergetic and biosynthetic requirements. During vascular injury, VSMCs switch from a quiescent “contractile”
Jia Shi, Yi Yang, Anying Cheng
exaly   +3 more sources

Senescence in Vascular Smooth Muscle Cells and Atherosclerosis

Frontiers in Cardiovascular Medicine, 2022
Vascular smooth muscle cells (VSMCs) are the primary cell type involved in the atherosclerosis process; senescent VSMCs are observed in both aged vessels and atherosclerotic plaques.
Yiwen Zha, Wenwen Zhuang, Yongqi Yang, Yue Zhou, Hongliang Li, Hongliang Li, Jingyan Liang, Jingyan Liang, Jingyan Liang   +8 more
doaj   +3 more sources

Diverse effects of calcineurin in vascular smooth muscle cells: physiological activators and the controversial actions of clinical inhibitors [PDF]

Frontiers in Pharmacology
Calcineurin is a serine/threonine phosphatase that classically regulates T cell activation and modulates immune response by targeting transcription factors of the NFaT family.
Alexander Nolze, Claudia Grossmann
doaj   +2 more sources

EPAC in Vascular Smooth Muscle Cells [PDF]

International Journal of Molecular Sciences, 2020
Vascular smooth muscle cells (VSMCs) are major components of blood vessels. They regulate physiological functions, such as vascular tone and blood flow. Under pathological conditions, VSMCs undergo a remodeling process known as phenotypic switching. During this process, VSMCs lose their contractility and acquire a synthetic phenotype, where they over ...
Nadine Wehbe, Suzanne Awni Nasser, Yusra Al-Dhaheri, Rabah Iratni, Alessandra Bitto, Ahmed F. El-Yazbi, Adnan Badran, Firas Kobeissy, Elias Baydoun, Ali H. Eid   +9 more
openaire   +3 more sources

Role of smooth muscle progenitor cells in vascular mechanical injury and repair

Medicine in Novel Technology and Devices, 2022
Smooth muscle progenitor cells are precursor cells that express both smooth muscle cell and stem cell markers, and can differentiate into smooth muscle cells under specific condition.
Zhu-feng Dong, Yan Long, Wen-jie Sun, Yang Wang, Yu-hua Huang, Gui-xue Wang, Bin He, Tie-ying Yin   +7 more
doaj   +1 more source

Long non-coding RNAs: Modulators of phenotypic transformation in vascular smooth muscle cells

Frontiers in Cardiovascular Medicine, 2022
Long non-coding RNA (lncRNAs) are longer than 200 nucleotides and cannot encode proteins but can regulate the expression of genes through epigenetic, transcriptional, and post-transcriptional modifications.
Bing-Han Lu, Bing-Han Lu, Hui-Bing Liu, Hui-Bing Liu, Hui-Bing Liu, Shu-Xun Guo, Shu-Xun Guo, Jie Zhang, Jie Zhang, Dong-Xu Li, Dong-Xu Li, Zhi-Gang Chen, Zhi-Gang Chen, Fei Lin, Fei Lin, Guo-An Zhao, Guo-An Zhao   +16 more
doaj   +1 more source

Vinpocetine Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells. [PDF]

PLoS ONE, 2016
Vascular calcification is an active process of osteoblastic differentiation of vascular smooth muscle cells; however, its definite mechanism remains unknown.
Yun-Yun Ma, Lin Sun, Xiu-Juan Chen, Na Wang, Peng-Fei Yi, Min Song, Bo Zhang, Yu-Zhong Wang, Qiu-Hua Liang   +8 more
doaj   +1 more source

Transcription factor GATA6 promotes migration of human coronary artery smooth muscle cells in vitro

Frontiers in Physiology, 2022
Vascular smooth muscle cell plasticity plays a pivotal role in the pathophysiology of vascular diseases. Despite compelling evidence demonstrating the importance of transcription factor GATA6 in vascular smooth muscle, the functional role of GATA6 ...
Azra Alajbegovic, Fatima Daoud, Fatima Daoud, Neserin Ali, Katarzyna Kawka, Johan Holmberg, Sebastian Albinsson   +6 more
doaj   +1 more source

Smoothelin in Vascular Smooth Muscle Cells [PDF]

Trends in Cardiovascular Medicine, 2007
Smoothelin-A and -B have only been found in fully differentiated contractile smooth muscle cells. They are increasingly used to monitor the smooth muscle cell differentiation process to a contractile or synthetic phenotype. Vascular-specific smoothelin-B is the first smooth muscle cell marker that disappears when vascular tissues are compromised, for ...
van Eys, G.J.J.M., Niessen, P.M.G., Rensen, S.S.M.   +2 more
openaire   +3 more sources