Results 51 to 60 of about 143,500 (200)

Lessons learnt from progressive vascular calcification in a renal transplant recipient

open access: yesIndian Journal of Transplantation, 2022
Chronic kidney disease − mineral bone disorder is a common complication in patients with renal failure. Vascular calcification is the part of this clinical syndrome and progresses over the years.
Urmila Anandh, Ritesh Kumar, G Ramesh
doaj   +1 more source

Association of serum fetuin-A and biochemical parameters in hemodialysis patients. [PDF]

open access: yes, 2014
Fetuin-A, a hepatic glycoprotein present in the circulation, is a potential inhibitor for systemic calcification. The main aim of this study was to evaluate the association between fetuin-A and other biochemical parameters as facilitator factors for ...
Besharat, S.   +5 more
core   +2 more sources

Relationship between effective blood flow rate and clinical outcomes in maintenance hemodialysis patients: a single-center study

open access: yesRenal Failure
The association between blood flow rate (BFR) and clinical outcomes in patients undergoing maintenance hemodialysis (MHD) is inconclusive. This retrospective study included 175 patients undergoing MHD treatment between July 2015 and March 2022, divided ...
Zhoucang Zhang   +5 more
doaj   +1 more source

Liver kinase B1 inhibits smooth muscle calcification via high mobility group box 1

open access: yesRedox Biology, 2021
Vascular calcification is a common pathological feature of atherosclerosis, chronic kidney disease, vascular injury, and aging. Liver kinase B1 (LKB1) plays pivotal roles in cellular processes such as apoptosis, metabolism, and cell cycle regulation.
Tianran Zhang   +10 more
doaj   +1 more source

The living aortic valve: From molecules to function. [PDF]

open access: yes, 2014
The aortic valve lies in a unique hemodynamic environment, one characterized by a range of stresses (shear stress, bending forces, loading forces and strain) that vary in intensity and direction throughout the cardiac cycle.
Bertazzo, S   +5 more
core   +1 more source

Sclerostin: Another Vascular Calcification Inhibitor? [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 2013
Sclerostin, a Wnt antagonist produced by osteocytes, regulates osteoblast activity and is a well-established key player in bone turnover. Recent data indicate that the Wnt pathway may also be involved in vascular calcification.The present study tests the hypothesis that serum sclerostin levels are associated with vascular calcification in patients with
Claes, Kathleen J.   +5 more
openaire   +3 more sources

Biological niches within human calcified aortic valves. Towards understanding of the pathological biomineralization process [PDF]

open access: yes, 2015
Despite recent advances, mineralization site, its microarchitecture, and composition in calcific heart valve remain poorly understood. A multiscale investigation, using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and ...
Cavarretta, Elena   +6 more
core   +8 more sources

Comparative efficacy of sodium thiosulfate, bisphosphonates, and cinacalcet for the treatment of vascular calcification in patients with haemodialysis: a systematic review and network meta-analysis

open access: yesBMC Nephrology
Background Up to now, there is no unequivocal intervention to mitigate vascular calcification (VC) in patients with hemodialysis. This network meta-analysis aimed to systematically evaluate the clinical efficacy of sodium thiosulfate, bisphosphonates ...
Lei He   +5 more
doaj   +1 more source

Caspase-independent programmed cell death triggers Ca2PO4 deposition in an in vitro model of nephrocalcinosis [PDF]

open access: yes, 2018
We provide evidence of caspase-independent cell death triggering the calcification process in GDNF-silenced HK-2 ...
Anglani F.   +8 more
core   +1 more source

The emerging roles of irisin in vascular calcification

open access: yesFrontiers in Endocrinology
Vascular calcification is a common accompanying pathological change in many chronic diseases, which is caused by calcium deposition in the blood vessel wall and leads to abnormal blood vessel function.
Shuangshuang Wang, Siwang Hu, Yuping Pan
doaj   +1 more source

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