Genetic Diagnoses Among Congenital Anomaly Cases in Europe: Data From the EUROCAT Network
Paediatric and Perinatal Epidemiology, EarlyView.ABSTRACT Background Surveillance of congenital anomaly prevalence over time can identify new teratogens. Anomalies with a genetic cause are excluded from the monitoring. Objectives We examined temporal changes in the proportion of genetic diagnoses among cases with a congenital anomaly.
Jorieke E. H. Bergman +23 more
wiley +1 more source
Vasopressor mechanisms in acute aortic coarctation hypertension
Brazilian Journal of Medical and Biological Research, 1997 Angiotensin II (ANG II) and vasopressin (AVP) act together with the mechanical effect of aortic constriction in the onset of acute aortic coarctation hypertension. Blockade of ANG II and AVP V1 receptors demonstrated that ANG II acts on the prompt (5 min)
Salgado H.C. +2 more
doaj
Congenital Coarctation of the Aorta in a Patient With ROBO4 c.695C>T (p.Thr232Met) Germline Variant
Annals of Internal Medicine: Clinical CasesRoundabout guidance receptor 4 (ROBO4) germline variants [including c.695C>T (p.Thr232Met)] have been linked with bicuspid aortic valve and thoracic aortic aneurysm. However, the precise nature of ROBO4’s role in aortopathy is yet to be fully defined. We
Mohammad Karam Chaaban +5 more
doaj +1 more source
Anomalous left coronary artery arising from the left pulmonary artery, aortic coarctation, and a large ventricular septal defect [PDF]
, 2006 J. Murala +5 more
openalex +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Experimental Physiology, EarlyView.Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
Prospective multicenter study of the breakable babystent for treatment of aortic coarctation in newborns and infants [PDF]
, 2022 Brigitte Stiller +9 more
openalex +1 more source
Experimental Physiology, EarlyView.Abstract Over the past three decades, there has been a steady increase in clinical attention to ischaemic heart failure caused by coronary microembolization. Nonetheless, a suitable mouse model for studying this condition remains limited. In the present study, we developed a mouse model of coronary microembolization‐induced ischaemic heart failure by ...
Lang Pei +10 more
wiley +1 more source
Transcatheter stent implantation to treat aortic coarctation in infancy. [PDF]
, 1993 Andrew N. Redington +2 more
openalex +1 more source
Microelectrode recordings from the human cervical vagus nerve during maximal breath‐holds
Experimental Physiology, EarlyView.Abstract Voluntary breath‐holds can be sustained for a long time following training, but ultimately, regardless of duration, the asphyxic break‐point is reached and the apnoea terminated. The physiological changes occurring during the apnoea include a marked increase in sympathetically‐mediated vasoconstriction in non‐essential organs, such as skeletal
Vaughan G. Macefield +7 more
wiley +1 more source
EuroSCORE II: Current limitations and physiological gaps in risk stratification
Experimental Physiology, EarlyView.Abstract Risk stratification remains critical in cardiac surgery, enabling clinicians to predict adverse outcomes and guide perioperative management. The European System for Cardiac Operative Risk Evaluation (EuroSCORE) II, introduced in 2011, incorporates 18 key variables to provide an evidence‐based approach to risk assessment.
Jing Yong Ng +7 more
wiley +1 more source