Results 121 to 130 of about 18,291 (287)

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Hypertension and Abdominal Pain After Resection of Aortic Coarctation

, 1970
Roy L. Tawes, John C. Bull, Benson B. Roe   +2 more
openalex   +2 more sources

Aortic pseudo-coarctation: spiral volumetric computed tomography imaging [PDF]

, 1999
Paolo Masiello, Giuseppe Santoro, Emilio Franzesi, Laura De Lillo, O Fittipaldi, Giuseppe Di Benedetto   +5 more
openalex   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Hypertension of Aortic Coarctation

, 1977
John C. Ferguson, W W Barrie, Worthington G. Schenk   +2 more
openalex   +2 more sources

High Concordance of Copy Number Variants Detected by Chromosomal Microarray and Exome Sequencing in Clinical Diagnostics

Clinical Genetics, EarlyView.
To assess the relevance of exome sequencing as a first‐tier diagnostic tool, three aspects were investigated: detection of copy number variants (CNVs) from exomes as compared to chromosomal microarray, clinically‐relevant CNVs across all sizes, and additional diagnostic utilities (uniparental disomy and triploidy).
Rivka Birnbaum, Maya Slovik, Shamir Zenvirt, Ilana Livyatan, Israel Altman, Shiri Gershon, Jonathan Rips, Hagit Daum, Chaggai Rosenbluh, Orly Elpeleg, Vardiella Meiner, Ayala Frumkin, Hagar Mor‐Shaked, Tamar Harel   +13 more
wiley   +1 more source

Doppler ultrasound in the assessment of severity of coarctation of the aorta and interruption of the aortic arch.

, 1987
A B Houston, Iain A. Simpson, James Pollock, M.P.G. Jamieson, W B Doig, E N Coleman   +5 more
openalex   +1 more source

Tetralogy of fallot and aortic coarctation. A rare association [PDF]

, 1999
Renata Cristina de Santana, Vitor Guerra, Nana Miura Ikari, Munir Ebaid   +3 more
openalex   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Complete aortic coarctation

Revista Portuguesa de Cardiologia (English Edition), 2016
José Alberto San Román, Christian Ortega-Loubon, Ana Revilla, Salvatore Di Stefano   +3 more
openaire   +5 more sources