Results 131 to 140 of about 432,168 (371)

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli   +17 more
wiley   +1 more source

2.2 RE-REFLECTION OF BACKWARD PROPAGATING WAVES LEADS TO AMPLIFICATION OF THE FORWARD PRESSURE WAVE IN WAVE SEPARATION ANALYSIS

open access: yesArtery Research, 2015
Introduction: In wave separation analysis, the pressure wave is decomposed into a single forward and backward component, which actually compounds all forward and backward propagating waves.
Patrick Segers*   +3 more
doaj   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely   +14 more
wiley   +1 more source

A Coupled Experimental and Computational Approach to Quantify Deleterious Hemodynamics, Vascular Alterations, and Mechanisms of Long-Term Morbidity in Response to Aortic Coarctati [PDF]

open access: yes, 2012
Introduction Coarctation of the aorta (CoA) is associated with morbidity despite treatment. Although mechanisms remain elusive, abnormal hemodynamics and vascular biomechanics are implicated. We present a novel approach that facilitates quantification of
Dholakia, Ronak Jashwant   +8 more
core   +1 more source

Aortic stenosis intricacies beyond the valve: A bidirectional Mendelian randomization study

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Numerous observational studies have reported an association between calcific aortic valve stenosis (CAVS) and an increased risk of other cardiovascular diseases (CVDs). However, the potential causal association is uncertain. Methods and results A bidirectional Mendelian randomization (MR) analysis was performed to confirm the causal ...
Dihui Cai, Jianhui Liu
wiley   +1 more source

Multiorgan characterization of inflammasome component expression in a rat model of advanced heart failure

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Targeting inflammasomes in heart failure (HF) might represent a novel therapeutic option. Nevertheless, previous studies focused only on myocardial inflammasome alterations, and data are scarce regarding their regulation and role in HF‐associated multiorgan dysfunction.
Dávid Nagy   +12 more
wiley   +1 more source

Facilitators, barriers, and insights using an HFA‐PEFF‐based clinical decision support system: A proof‐of‐concept study

open access: yesESC Heart Failure, EarlyView.
Analysis of the usage of the HFA‐PEFF score‐based clinical decision support system (CDSS) and the main barriers and facilitators to its implementation, based on a survey of physicians. Abstract Background and aims Knowing that heart failure (HF) with preserved ejection fraction (HFpEF) can be difficult to diagnose, a clinical decision support system ...
Isidora Milosavljević   +29 more
wiley   +1 more source

Partial cardiopulmonary bypass through left thoracotomy for coarctation repair in children

open access: yesJournal of Cardiothoracic Surgery
Background A left thoracotomy approach is anatomically appropriate for childhood aortic coarctation; however, the pediatric femoral arteriovenous diameters are too small for cardiopulmonary bypass cannulation.
Kunihiko Joo   +8 more
doaj   +1 more source

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