Results 171 to 180 of about 26,000 (247)

From Tumor Marker to Congestion Indicator: The Expanding Role of CA‐125 in Heart Failure and Beyond

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims To evaluate the transition of Carbohydrate antigen 125 (CA‐125) from an ovarian tumor marker to a versatile indicator of systemic congestion and fluid overload. Methods A literature review (1984–2025) was conducted using PubMed, Scopus, and Web of Science. Keywords included “CA‐125,” “systemic congestion,” and related terms.
Minoo Heidari Almasi   +4 more
wiley   +1 more source

The Sooner, the Better: Neuroprotective Strategies in Fetuses With Congenital Heart Disease

open access: yesPrenatal Diagnosis, Volume 46, Issue 3, Page 368-381, March 2026.
ABSTRACT Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion and oxygenation, which negatively affects brain growth and maturation.
Maaike Nijman   +7 more
wiley   +1 more source

Connecting the Dots: A Semantic Network Approach to Pediatric iNO Research Discovery

open access: yesWIREs Data Mining and Knowledge Discovery, Volume 16, Issue 1, March 2026.
Semantic Reconstruction of Pediatric iNO Research: From Lexical Networks to Translational Insight. This graphical abstract summarizes a computational framework used to map the historical and semantic evolution of inhaled nitric oxide (iNO) research in pediatric cardiac surgery.
S. Fernando Gomes Jr   +7 more
wiley   +1 more source

High Concordance of Copy Number Variants Detected by Chromosomal Microarray and Exome Sequencing in Clinical Diagnostics

open access: yesClinical Genetics, Volume 109, Issue 3, Page 529-538, March 2026.
To assess the relevance of exome sequencing as a first‐tier diagnostic tool, three aspects were investigated: detection of copy number variants (CNVs) from exomes as compared to chromosomal microarray, clinically‐relevant CNVs across all sizes, and additional diagnostic utilities (uniparental disomy and triploidy).
Rivka Birnbaum   +13 more
wiley   +1 more source

Establishment of a mouse model for ischaemic heart failure induced by coronary microembolization via left ventricular oil injection

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1039-1057, 1 March 2026.
Abstract Over the past three decades, there has been a steady increase in clinical attention to ischaemic heart failure caused by coronary microembolization. Nonetheless, a suitable mouse model for studying this condition remains limited. In the present study, we developed a mouse model of coronary microembolization‐induced ischaemic heart failure by ...
Lang Pei   +10 more
wiley   +1 more source

A Rare Cause of Severe Aortic Coarctation in an Adolescent: Coral Reef Aorta. [PDF]

open access: yesWorld J Pediatr Congenit Heart Surg
Kızılkaya MH   +6 more
europepmc   +1 more source

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