Results 181 to 190 of about 479,259 (314)

Optimizing Diagnostic Accuracy of Clinical Red Flags in RASopathies

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1608-1618, July 2026.
ABSTRACT RASopathies are a group of genetic disorders caused by pathogenic variants in the RAS‐mitogen‐activated protein kinase (RAS–MAPK) signaling pathway, often presenting with congenital heart defects, craniofacial dysmorphisms, and developmental delays. To assess the diagnostic yield of genetic testing in patients with suspected RASopathies and to
Emanuele Bobbio, Martina Caiazza, Emanuele Monda, Giustina Aruta, Alberto Budillon, Augusto Esposito, Adelaide Fusco, Annapaola Cirillo, Marta Rubino, Immacolata Viscovo, Gioacchino Scarano, Matteo Della Monica, Vincenzo Nigro, Giulio Piluso, Leandro Pecchia, Maria Giovanna Russo, Giuseppe Limongelli   +16 more
wiley   +1 more source

Testicular pain as an unusual presenting symptom of aortic coarctation: a case report and review of the literature. [PDF]

Int J Emerg Med
Basazinew E, Alemayehu T, Werede A, Teferi M, Alemayehu B, Derso G, Kefyalew M.   +6 more
europepmc   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12 ‐Related Developmental Disorders

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1619-1650, July 2026.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Delayed presentation of aortic coarctation as an aortic dissection: a case report. [PDF]

Ann Med Surg (Lond)
Fayisa S, Shanko D, Admasu W, Aman S, Abdurahman H, Musema A.   +5 more
europepmc   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, Volume 183, Issue 13, Page 3762-3779, July 2026.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

Late Complications After Aortic Coarctation Repair. [PDF]

J Cardiovasc Dev Dis
Santoro A, De Lisio F, Fedorovna Bezborodova A, Chiesa R, Melissano G.   +4 more
europepmc   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, Volume 38, Issue 31, 2 June 2026.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Multimodality Imaging Approach in Diagnosis and Follow-Up of Aortic Coarctation in Adulthood. [PDF]

J Clin Med
La Mura L, Mannacio L, Illuminato F, Ferrone M, Lembo M, D'Elia S, Izzo C, Santoro C, Izzo R.   +8 more
europepmc   +1 more source

A Rare Vascular Ring Malformation Formed by Right Aortic Arch With Mirror Image Branching Causing Dysphagia: Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT A right‐sided aortic arch, a congenital anomaly of the aortic arch, was initially described by Fioratti and Aglietti in 1963. This condition, associated with formation of a vascular ring, can constrict mediastinal organs such as the trachea and esophagus.
Md. Deluwar Hussen, Lamia Rashid, Maliha Zahir, Nurjahan Dilshad, Md. Atique Faisal Tanim, Md Mahfuzur Rahman Zeehad   +5 more
wiley   +1 more source

Aortic Valve Stenosis and Insufficiency Combined With Aortic Coarctation. [PDF]

JACC Case Rep
Hu T, Tu W, Li L.
europepmc   +1 more source