Results 171 to 180 of about 26,235 (263)

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, Volume 40, Issue 5, Page 2878-2894, May 2026.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source

Single-stage surgical modification for neonatal aortic coarctation and ventricular septal defect: a case report. [PDF]

Eur Heart J Case Rep
Yang X, Xing P, Hou K, Chen R, Pan S.
europepmc   +1 more source

Postoperative chylothorax following surgical transection of a left ligamentum arteriosum in a cat with a persistent right aortic arch

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 6‐month‐old intact female domestic shorthair cat was presented for surgical correction of a vascular ring anomaly. The main clinical sign on presentation was persistent regurgitation after ingestion of solid food. Computed tomography of the thorax confirmed the diagnosis of a persistent right aortic arch (PRAA) with a left ligamentum ...
Adriaan D. Pont, Elizabeth G. Bester, Adriaan M. Kitshoff   +2 more
wiley   +1 more source

Severe Coronary Artery Disease and Nearly Atretic Aortic Coarctation in a Young Woman. [PDF]

JACC Case Rep
Ghardallou H, Chelly A, Ben Saad S, Ghedhami E, Slim M, Neffati E.   +5 more
europepmc   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, Volume 183, Issue 9, Page 1939-1957, May 2026.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Surgical Induction of Mid-Thoracic Aortic Coarctation in Mice: A Reproducible Preclinical Model of Pressure-Induced Vascular Remodeling. [PDF]

Curr Protoc
Lauver DA, Garver H, Kreiger-Burke T, Rendón CJ, Contreras GA, Watts SW, Fink GD.   +6 more
europepmc   +1 more source

Prevalence and Spectrum of Congenital Heart Disease in Individuals With Distal Chromosome 22q11.22–23 Deletions

Clinical Genetics, Volume 109, Issue 5, Page 859-868, May 2026.
The frequency and severity of congenital heart disease vary extensively in individuals with 22q11.22–23 distal deletions. Reduced gene dosage particularly within the low copy repeat (LCR22) D–E region including MAPK1 and HIC2 conveys risk for these defects.
Tanner J. Nelson, Daniel E. McGinn, T. Blaine Crowley, Lydia Rockart, Audrey Green, Victoria Giunta, Oanh Tran, Daniella Miller, Jeroen Breckpot, Ann Swillen, M. Cristina Digilio, Marta Unolt, Carolina Putotto, Federica Pulvirenti, Bruno Marino, Beverly S. Emanuel, Elaine H. Zackai, Zhengdong D. Zhang, Elizabeth Goldmuntz, Erik Boot, Anne S. Bassett, Bernice E. Morrow, Donna M. McDonald‐McGinn   +22 more
wiley   +1 more source

Management and Prognosis of Patients With Acute Pericarditis in the Emergency Department: A Retrospective, Single‐Centre Study

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
In this retrospective, single‐centre study conducted in patients with acute pericarditis referred to the Emergency Department, a significant proportion of patients experienced long‐term complications, especially recurrences. Drug doses were compliant with guidelines in a limited number of patients at admission and increased at discharge. Diabetes, COPD,
Lisa Caldera, Chiara Lovati, Alessandra Vecchié, Walter Ageno, Marco Paolo Donadini, Francesco Dentali, Flavio Tangianu, Aldo Bonaventura   +7 more
wiley   +1 more source

Incidence and Risk Factors of Recoarctation Following Surgical Repair of Aortic Coarctation in Infants: <i>A retrospective single-centre study</i>. [PDF]

Sultan Qaboos Univ Med J
Al Badi HA, Al Kindi H, Al Alawi K, Al Furqani A, Al Kindi L, Maddali MM.   +5 more
europepmc   +1 more source

Microvascular Effects of Endocannabinoid Signaling in Sepsis: A Mechanistic and Systematic Review

Microcirculation, Volume 33, Issue 4, May 2026.
ABSTRACT Microvascular dysfunction is a central determinant of organ failure in sepsis, reflecting early endothelial activation, increased permeability, and impaired capillary perfusion. Experimental evidence suggests that the endocannabinoid system (ECS) modulates these immunovascular processes, yet mechanistic insights remain dispersed across ...
Emanuel F. Matias, Francisco M. Vila‐Real, Maria A. Vieira‐Coelho   +2 more
wiley   +1 more source