Results 31 to 40 of about 886,119 (323)

Atenolol versus losartan in children and young adults with Marfan's syndrome [PDF]

, 2014
BACKGROUND : Aortic-root dissection is the leading cause of death in Marfan's syndrome. Studies suggest that with regard to slowing aortic-root enlargement, losartan may be more effective than beta-blockers, the current standard therapy in most centers.
Atz, A.M., Backer, J. de, Benson, D.W., Bradley, T.J., Braverman, A.C., Chen, S., Colan, S.D., Dietz, H.C., et al., Gelb, B.D., Grossfeld, P.D., Klein, G.L., Lacro, R.V., Lai, W.W., Levine, J.C., Liou, A., Loeys, B.L., Mahony, L., Markham, L.W., Olson, A.K., Paridon, S.M., Pearson, G.D., Pemberton, V.L., Pierpont, M.E., Pyeritz, R.E., Radojewski, E., Roman, M.J., Sharkey, A.M., Sleeper, L.A., Stylianou, M.P., Tierney, E.S., Wechsler, S.B., Yetman, A.T., Young, L.T.   +33 more
core   +2 more sources

TGFβ (transforming growth factor-β) blockade induces a human-like disease in a nondissecting mouse model of abdominal aortic aneurysm [PDF]

, 2017
Objective-Current experimental models of abdominal aortic aneurysm (AAA) do not accurately reproduce the major features of human AAA. We hypothesized that blockade of TGF beta (transforming growth factor-beta) activity-a guardian of vascular integrity ...
Clément, Marc, Esposito, Bruno, Finigan, Alison, Lareyre, Fabien, Mallat, Ziad, Master, Leanne, Patel, Meghana, Pohlod, Stefanie, Raffort, Juliette, Stergiopulos, Nikolaos, Taleb, Soraya, Trachet, Bram, Vandestienne, Marie   +12 more
core   +2 more sources

Evaluation of the aorta in infants with simple or complex coarctation of the aorta using CT angiography

Frontiers in Cardiovascular Medicine, 2023
ObjectiveTo assess aortic dilatation and determine its related factors in infants with coarctation of the aorta (CoA) by using computed tomography angiography (CTA).MethodsThe clinical data of 55 infantile patients with CoA diagnosed by CTA were analyzed
Hui-Jun Xiao, A-Lai Zhan, Qing-Wen Huang, Rui-Gang Huang, Wei-Hua Lin   +4 more
doaj   +1 more source

Left main bronchus compression due to main pulmonary artery dilatation in pulmonary hypertension: two case reports [PDF]

, 2015
. Pulmonary arterial dilatation associated with pulmonary hypertension may result in significant compression of local structures. Left main coronary artery and left recurrent laryngeal nerve compression have been described.
Ariff, B, Davies, R, Gibbs, JS, Gin-Sing, W, Howard, L, Jaijee, SK, O'Regan, DP   +6 more
core   +1 more source

Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling

Arteriosclerosis, Thrombosis and Vascular Biology, 2018
Objective— Thoracic aortic aneurysm (TAA), a degenerative disease of the aortic wall, is accompanied by changes in the structure and composition of the aortic ECM (extracellular matrix). The ADAMTS (a disintegrin and metalloproteinase with thrombospondin
M. Fava, J. Barallobre-Barreiro, U. Mayr, Ruifang Lu, A. Didangelos, F. Baig, Marc Lynch, N. Catibog, A. Joshi, T. Barwari, X. Yin, M. Jahangiri, M. Mayr   +12 more
semanticscholar   +2 more sources

Transforming growth factor serum concentrations in patients with proven non-syndromic aortopathy

Frontiers in Cardiovascular Medicine, 2022
BackgroundThe mechanism underlying aortic dilatation is still unknown. Vascular dilatation is thought to be the result of progressive aortic media degeneration caused by defective vascular matrix hemostasis, including TGF-β1 dysregulation.
Mikita Karalko, Marek Pojar, Lenka Zaloudkova, Vaclav Stejskal, Salifu Timbilla, Pavla Brizova, Jan Vojacek   +6 more
doaj   +1 more source

Evolution of the wall shear stresses during the progressive enlargement of symmetric abdominal aortic aneurysms. [PDF]

, 2006
The changes in the evolution of the spatial and temporal distribution of the wall shear stresses (WSS) and gradients of wall shear stresses (GWSS) at different stages of the enlargement of an abdominal aortic aneurysm (AAA) are important in understanding
Chomaz, JM, Lasheras, JC, Salsac, A-V, Sparks, SR   +3 more
core   +4 more sources

Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease

Journal of Cardiovascular Magnetic Resonance, 2018
BackgroundIn patients with bicuspid valve (BAV), ascending aorta (AAo) dilatation may be caused by altered flow patterns and wall shear stress (WSS). These differences may explain different aortic dilatation morphotypes.
J. Rodríguez-Palomares, L. Dux-Santoy, A. Guala, R. Kale, G. Maldonado, G. Teixidó-Turà, L. Galián, M. Huguet, F. Valente, L. Gutiérrez, T. González‐Alujas, Kevin M. Johnson, O. Wieben, D. Garcia-Dorado, A. Evangelista   +14 more
semanticscholar   +1 more source

Progressive thoracic aortic dilatation after aortic valve replacement [PDF]

American Journal of Roentgenology, 1984
Aneurysms of the ascending aorta developed after aortic valve replacement for chronic aortic insufficiency in four cases. Two of the aneurysms were complicated by dissection; one patient died. Rheumatic disease has become a less common cause of pure aortic regurgitation, and a number of etiologies primarily involving the wall of the aorta are now ...
P A, Nancarrow, C B, Higgins
openaire   +2 more sources

Prognostic value of echocardiographic indices of left atrial morphology and function in dogs with myxomatous mitral valve disease [PDF]

, 2018
Background: The prognostic relevance of left atrial (LA) morphological and functional variables, including those derived from speckle tracking echocardiography (STE), has been little investigated in veterinary medicine.
Baron Toaldo, Marco, Cipone, Mario, Contiero, Barbara, Diana, Alessia, Guglielmini, Carlo, Pelle, Nazzareno G., Romito, Giovanni   +6 more
core   +2 more sources