Results 41 to 50 of about 5,333,908 (203)

Inflammasome Targeted Therapy as Novel Treatment Option for Aortic Aneurysms and Dissections: A Systematic Review of the Preclinical Evidence

Frontiers in Cardiovascular Medicine, 2022
Both aortic aneurysm and dissection are life threatening pathologies. In the lack of a conservative medical treatment, the only therapy consists of modifying cardiovascular risk factors and either surgical or endovascular treatment.
Markus Wortmann, Rosa Klotz, Rosa Klotz, Eva Kalkum, Susanne Dihlmann, Dittmar Böckler, Andreas S. Peters   +6 more
doaj   +1 more source

Association between the difference in cystatin C and creatinine-based eGFR and risks of multiple cardiovascular diseases: a prospective cohort study

Frontiers in Medicine
BackgroundThe difference between cystatin C- and creatinine-based estimated glomerular filtration rate (eGFRdiff) is closely associated with various adverse outcomes. This study aims to comprehensively evaluate the association between eGFRdiff, all-cause
Zhiyu Qiao, Xinyi Liu, Hao Liu, Suwei Chen, Chengnan Li, Yipeng Ge, Haiou Hu, Junming Zhu   +7 more
doaj   +1 more source

Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach. [PDF]

, 2011
Abdominal aortic aneurysms (AAA) are characterized by pathological remodeling of the aortic extracellular matrix (ECM). However, besides the well-characterized elastolysis and collagenolysis little is known about changes in other ECM proteins.
Mandal, K, Marjan Jahangiri, Didangelos, Athanasios, Didangelos, A, Smith, A, Mandal, Kaushik, Saje, A, Smith, Alberto, Xu, Q, Jahangiri, M, Mayr, Manuel; id_orcid, Mayr, M, Athanasios Didangelos, Alberto Smith, Qingbo Xu, Jahangiri, Marjan, Kaushik Mandal, Angelika Saje, Saje, Angelika, Yin, Xiaoke; id_orcid, Xu, Qingbo, Xiaoke Yin, Manuel Mayr, Yin, X   +23 more
core   +1 more source

Coronary Artery Disease in Patients Undergoing Transvalvular Aortic Valve Implantation [PDF]

, 2022
Coronary artery disease (CAD) is common in patients with severe aortic stenosis. With the advent of transcatheter aortic valve implantation (TAVI) as a therapeutic option, management of CAD in such patients has undergone a revolution.
Edgar Tay, Yinghao Lim, Kent Anthony Tan, Ivandito Kuntjoro, Jimmy KF Hon, Hon, Jimmy KF, Tay, Edgar, Lim, Yinghao, Kuntjoro, Ivandito, Yip, James, James Yip, Tan, Kent Anthony   +11 more
core   +1 more source

Use of fenestrated-branched endovascular aneurysm repair to treat Carrel patch aneurysmal degeneration after open thoracoabdominal aortic aneurysm repair

Journal of Vascular Surgery Cases and Innovative Techniques, 2019
Two patients with a history of open type II thoracoabdominal aortic aneurysm repair presented with saccular aneurysmal degeneration of the Carrel patch.
Tammy T. Nguyen, MD, PhD, Jessica P. Simons, MD, MPH, Andres Schanzer, MD   +2 more
doaj   +1 more source

Patterns of genetic mutations explored by systematic screening of patients with aortopathy and their family membersCentral MessagePerspective

JTCVS Open, 2023
Objective: Genetic aortopathy, if left untreated, leads to aortic catastrophe in most affected individuals. We sought to determine the genetic mutation patterns and detection rates in patients with aortopathy and their families with a systematic ...
Jihoon Kim, MD, PhD, Jae Suk Yoo, MD, PhD, Hee-Jung Kim, MD, PhD, Ho Jin Kim, MD, Dae-Hee Kim, MD, PhD, Suk Jung Choo, MD, PhD, Joon Bum Kim, MD, PhD   +6 more
doaj   +1 more source

Accelerated biological aging, genetic susceptibility, and lifestyle in relation to abdominal aortic aneurysm: A prospective study

The Journal of Nutrition, Health and Aging
Objectives: This study aimed to investigate the associations of biological age (BA) acceleration and genetic risk with the incidence of abdominal aortic aneurysm (AAA), and to evaluate the extent to which BA acceleration mediates the impact of a healthy ...
Xinyi Liu, Yongliang Zhong, Suwei Chen, Chengnan Li, Yipeng Ge, Haiou Hu, Junming Zhu   +6 more
doaj   +1 more source

Approach to aortic aortic valve diseases in the elderly

Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology, 2017
Aortic valve diseases are the most common among the valvular heart diseases. Significant increases in the frequency of degenerative aortic sclerosis and aortic stenosis (AS) are observed, particularly with aging of the population and diminished rheumatic heart disease.
Bozkurt, Engin, Ayhan, Huseyin
openaire   +3 more sources

Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]

, 2010
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J, Landwehrmeyer, G Bernhard, Aileen K Ho, Bisson, Jonathan Ian, Schwenke C, David Craufurd, Dunnett, Stephen B., Handley, Olivia, Investigators of the European Huntington's Disease Network, The, DI MARIA, EMILIO, Craufurd D, Dunnett, SB, Carsten Schwenke, the investigators of the European Huntington's Disease Network, Craufurd, David, Edward Wild, Landwehrmeyer, GB, Busse, Monica, Rosser, Anne Elizabeth, Olivia J Handley, Romano Silvia., Tabrizi SJ, Ho, Aileen K., Wild, E, Landwehrmeyer GB, Craufurd, D, Tabrizi, SJ, Tabrizi, Sarah J., Handley, OJ, Rickards, Hugh, Dunnett, Stephen, Ho, Aileen K, Orth, Michael, Ho, AK, Wild, Edward, Stephen B. Dunnett, Sarah J Tabrizi, Wild, EJ, Landwehrmeyer, G. Bernhard, Naji, Jenny, Landwehrmeyer, G. Bernhard, Wild E, Investigators of the European Huntington's Disease Network, Handley, Olivia J., Orth, M, Ellison-Rose, Lynda, Tabrizi, Sarah J, Price, Kathleen, Ho AK, ABBRUZZESE, GIOVANNI, Schwenke, C, Ho, A, Orth M, Handley OJ, Schwenke, Carsten, Dunnett SB, Dunnett, Stephen B, Michael Orth, G. Bernhard Landwehrmeyer   +59 more
core   +1 more source

Prospective analysis of metabolic syndrome and inflammation in aortic aneurysm risk: UK Biobank study

Frontiers in Endocrinology
Context/ObjectivesMetabolic syndrome (MetS) is associated with various diseases, yet its connection with aortic aneurysm (AA) is not well understood. The role of chronic inflammation as a mediator in this relationship also remains unclear.
Xinyi Liu, Hao Liu, Suwei Chen, Chen Gong, Yipeng Ge, Zhiyu Qiao, Chengnan Li, Junming Zhu   +7 more
doaj   +1 more source