Results 1 to 10 of about 16,233 (141)

Rare regulatory mutations disrupt mesenchymal molecular programs driving endocardial cushion formation in bicuspid aortic valve [PDF]

Nature Communications
Bicuspid aortic valve, a prevalent congenital malformation, predisposes individuals to severe complications. Although the condition exhibits substantial heritability, known protein-coding and common regulatory mutations explain a minority of cases.
Artemy Zhigulev, Andrey Buyan, Enikő Lázár, Nikita Gryzunov, Karin Lång, Raphaël Mauron, Vladimir Nozdrin, Rapolas Spalinskas, Sailendra Pradhananga, Madeleine Petersson Sjögren, Doreen Schwochow, Anders Franco-Cereceda, Joakim Lundeberg, Ivan V. Kulakovskiy, Per Eriksson, Hanna M. Björck, Pelin Sahlén   +16 more
doaj   +2 more sources

Transcatheter Treatment of Bicuspid Aortic Valve Stenosis: From Observational Studies to Randomized Clinical Trials [PDF]

Structural Heart
Bicuspid aortic valve (BAV) disease is the most common congenital heart abnormality, which affects up to 2% of the population and significantly increases the lifetime risk of aortic stenosis and the need for valve replacement. While surgical aortic valve
Daryoush Samim, MD, Matthias Siepe, MD, Peter Jüni, MD, Aakriti Gupta, MD, Hasan Jilaihawi, MD, Michael A. Borger, MD-PhD, Raj R. Makkar, MD, Martin B. Leon, MD, Stephan Windecker, MD   +8 more
doaj   +2 more sources

Bicuspid aortic valve [PDF]

Annals of Cardiothoracic Surgery, 2017
Bicuspid aortic valve (BAV) has a prevalence of 0.5–1.39% in the general population. The prevalence of BAV in aortic dissection is 3.5–11.8%. Unfortunately, the incidence of aortic dissection in BAV remains unknown. The etiology of BAV is polygenetic, where environmental factors and unknown genetic factors seem to interact to cause BAV.
Christopher, Harris, Beth, Croce, Stine, Munkholm-Larsen   +2 more
  +5 more sources

The first clinical data of the SAPIEN 3 aortic valve in the treatment of aortic stenosis in China

Frontiers in Cardiovascular Medicine, 2023
BackgroundData on outcomes following transcatheter aortic valve replacement with SAPIEN 3 in China is limited as it was approved by the National Medical Products since 2020.
Xiaoke Shang, Xiangbin Pan, Gejun Zhang, Zhengming Jiang, Xianbao Liu, Guangyuan Song, Yi Li, Yan Wang, Jianfang Luo, Yida Tang, Yiqiang Yuan, Yongjian Wu, Xiang Ma, Dan Zhu, Yucheng Zhong, Changdong Zhang, Nianguo Dong   +16 more
doaj   +1 more source

The Hammock Sign in Computed Tomography as a Detection Aid for Bicuspid Aortic Valves

Journal of the Belgian Society of Radiology, 2023
Introduction: Bicuspid aortic valve is difficult to detect on standard transverse images. Purpose: We aimed to investigate the usefulness of the hammock sign for detection of bicuspid aortic valve.
Daniel Devos, Charlotte Van Langenhove, Laurence Campens   +2 more
doaj   +1 more source

Bicuspid aortic valve outcomes [PDF]

Cardiology in the Young, 2016
AbstractBackgroundBicuspid aortic valve is the most common CHD. Its association with early valvular dysfunction, endocarditis, thoracic aorta dilatation, and aortic dissection is well established.ObjectiveThe aim of this study was to assess the incidence and predictors of cardiac events in adults with bicuspid aortic valve.MethodsWe carried out a ...
Rodrigues, I, Agapito, A, Sousa, L, Oliveira, JA, Branco, LM, Galrinho, A, Abreu, J, Timóteo, AT, Aguiar Rosa, S, Cruz Ferreira, R   +9 more
openaire   +3 more sources

Aortic annulus sizing in bicuspid and tricuspid aortic valves using CT in patients with surgical aortic valve replacement

Scientific Reports, 2021
The purpose of this study was to evaluate whether bicuspid anatomy affects the discrepancy between CT-derived annular size and intraoperative size. We retrospectively analyzed annular measurements in 667 patients who underwent surgical aortic valve ...
Jooae Choe, Hyun Jung Koo, Joon-Won Kang, Joon Bum Kim, Hee Jun Kang, Dong Hyun Yang   +5 more
doaj   +1 more source

Determinants of device success after transcatheter aortic valve replacement in patients with type-0 bicuspid aortic stenosis

Frontiers in Cardiovascular Medicine, 2023
BackgroundClinical evidence of transcatheter aortic valve replacement in patients with type-0 bicuspid aortic valve was relatively scarce.AimsOur goal was to explore determinants of device success after transcatheter aortic valve replacement in patients ...
Zhicheng Xiao, Jing Yao, Xinmin Liu, Fei Yuan, Yunfeng Yan, Taiyang Luo, Moyang Wang, Hongliang Zhang, Faxin Ren, Guangyuan Song   +9 more
doaj   +1 more source

Infective endocarditis risk in patients with bicuspid aortic valve: Systematic review and meta-analysis

International Journal of Cardiology: Heart & Vasculature, 2023
Background: Antibiotic prophylaxis in bicuspid aortic valve patients is currently a matter of debate. Although it is no longer recommended by international guidelines, some studies indicate a high risk of infective endocarditis.
Sara Couto Pereira, Ana Lobato Abrantes, Pedro Silverio António, Pedro Morais, Catarina Sousa, Cláudio David, Fausto J. Pinto, Ana G. Almeida, Daniel Caldeira   +8 more
doaj   +1 more source

Anterograde crossing of a bicuspid aortic valve through transseptal access to facilitate transcatheter aortic valve implantation

Heart Views, 2021
Transcatheter aortic valve implantation (TAVI) for bicuspid aortic valve stenosis can pose several technical challenges including difficult valve crossing.
Bilal Bawamia, Douglas Muir, Seth Vijayan, Paul Williams   +3 more
doaj   +1 more source