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Bicuspid Aortic Valve Disease: A Comprehensive Review [PDF]

Cardiology Research and Practice, 2012
Bicuspid aortic valve is the commonest congenital cardiac abnormality in the general population. This paper article will discuss our current knowledge of the anatomy, pathophysiology, genetics, and clinical aspects of bicuspid aortic valve disease.
Ify Mordi, Nikolaos Tzemos
doaj   +5 more sources

Rare regulatory mutations disrupt mesenchymal molecular programs driving endocardial cushion formation in bicuspid aortic valve [PDF]

Nature Communications
Bicuspid aortic valve, a prevalent congenital malformation, predisposes individuals to severe complications. Although the condition exhibits substantial heritability, known protein-coding and common regulatory mutations explain a minority of cases.
Artemy Zhigulev, Andrey Buyan, Enikő Lázár, Nikita Gryzunov, Karin Lång, Raphaël Mauron, Vladimir Nozdrin, Rapolas Spalinskas, Sailendra Pradhananga, Madeleine Petersson Sjögren, Doreen Schwochow, Anders Franco-Cereceda, Joakim Lundeberg, Ivan V. Kulakovskiy, Per Eriksson, Hanna M. Björck, Pelin Sahlén   +16 more
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Transcatheter Treatment of Bicuspid Aortic Valve Stenosis: From Observational Studies to Randomized Clinical Trials [PDF]

Structural Heart
Bicuspid aortic valve (BAV) disease is the most common congenital heart abnormality, which affects up to 2% of the population and significantly increases the lifetime risk of aortic stenosis and the need for valve replacement. While surgical aortic valve
Daryoush Samim, MD, Matthias Siepe, MD, Peter Jüni, MD, Aakriti Gupta, MD, Hasan Jilaihawi, MD, Michael A. Borger, MD-PhD, Raj R. Makkar, MD, Martin B. Leon, MD, Stephan Windecker, MD   +8 more
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Bicuspid aortic valve [PDF]

Annals of Cardiothoracic Surgery, 2017
Bicuspid aortic valve (BAV) has a prevalence of 0.5–1.39% in the general population. The prevalence of BAV in aortic dissection is 3.5–11.8%. Unfortunately, the incidence of aortic dissection in BAV remains unknown. The etiology of BAV is polygenetic, where environmental factors and unknown genetic factors seem to interact to cause BAV.
Christopher, Harris, Beth, Croce, Stine, Munkholm-Larsen   +2 more
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The first clinical data of the SAPIEN 3 aortic valve in the treatment of aortic stenosis in China

Frontiers in Cardiovascular Medicine, 2023
BackgroundData on outcomes following transcatheter aortic valve replacement with SAPIEN 3 in China is limited as it was approved by the National Medical Products since 2020.
Xiaoke Shang, Xiangbin Pan, Gejun Zhang, Zhengming Jiang, Xianbao Liu, Guangyuan Song, Yi Li, Yan Wang, Jianfang Luo, Yida Tang, Yiqiang Yuan, Yongjian Wu, Xiang Ma, Dan Zhu, Yucheng Zhong, Changdong Zhang, Nianguo Dong   +16 more
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The Hammock Sign in Computed Tomography as a Detection Aid for Bicuspid Aortic Valves

Journal of the Belgian Society of Radiology, 2023
Introduction: Bicuspid aortic valve is difficult to detect on standard transverse images. Purpose: We aimed to investigate the usefulness of the hammock sign for detection of bicuspid aortic valve.
Daniel Devos, Charlotte Van Langenhove, Laurence Campens   +2 more
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Bicuspid aortic valve outcomes [PDF]

Cardiology in the Young, 2016
AbstractBackgroundBicuspid aortic valve is the most common CHD. Its association with early valvular dysfunction, endocarditis, thoracic aorta dilatation, and aortic dissection is well established.ObjectiveThe aim of this study was to assess the incidence and predictors of cardiac events in adults with bicuspid aortic valve.MethodsWe carried out a ...
Rodrigues, I, Agapito, A, Sousa, L, Oliveira, JA, Branco, LM, Galrinho, A, Abreu, J, Timóteo, AT, Aguiar Rosa, S, Cruz Ferreira, R   +9 more
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Bicuspid aortic valve disease [PDF]

Canadian Medical Association Journal, 2013
Bicuspid aortic valves are present in 1%–2% of the population, with men being 3 times more commonly affected than women. This disease is more than just anatomic variation and may be associated with other heart and aorta abnormalities as a result of molecular and connective tissue derangements.[1][
Katie L, Losenno, Michael W A, Chu
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Aortic annulus sizing in bicuspid and tricuspid aortic valves using CT in patients with surgical aortic valve replacement

Scientific Reports, 2021
The purpose of this study was to evaluate whether bicuspid anatomy affects the discrepancy between CT-derived annular size and intraoperative size. We retrospectively analyzed annular measurements in 667 patients who underwent surgical aortic valve ...
Jooae Choe, Hyun Jung Koo, Joon-Won Kang, Joon Bum Kim, Hee Jun Kang, Dong Hyun Yang   +5 more
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Determinants of device success after transcatheter aortic valve replacement in patients with type-0 bicuspid aortic stenosis

Frontiers in Cardiovascular Medicine, 2023
BackgroundClinical evidence of transcatheter aortic valve replacement in patients with type-0 bicuspid aortic valve was relatively scarce.AimsOur goal was to explore determinants of device success after transcatheter aortic valve replacement in patients ...
Zhicheng Xiao, Jing Yao, Xinmin Liu, Fei Yuan, Yunfeng Yan, Taiyang Luo, Moyang Wang, Hongliang Zhang, Faxin Ren, Guangyuan Song   +9 more
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