Results 1 to 10 of about 13,922 (152)

Elucidation of the genetic causes of bicuspid aortic valve disease. [PDF]

Cardiovasc Res, 2023
Abstract Aims The present study aims to characterize the genetic risk architecture of bicuspid aortic valve (BAV) disease, the most common congenital heart defect. Methods and results We carried out a genome-wide association study ...
Gehlen J, Stundl A, Debiec R, Fontana F, Krane M, Sharipova D, Nelson CP, Al-Kassou B, Giel AS, Sinning JM, Bruenger CMH, Zelck CF, Koebbe LL, Braund PS, Webb TR, Hetherington S, Ensminger S, Fujita B, Mohamed SA, Shrestha M, Krueger H, Siepe M, Kari FA, Nordbeck P, Buravezky L, Kelm M, Veulemans V, Adam M, Baldus S, Laugwitz KL, Haas Y, Karck M, Mehlhorn U, Conzelmann LO, Breitenbach I, Lebherz C, Urbanski P, Kim WK, Kandels J, Ellinghaus D, Nowak-Goettl U, Hoffmann P, Wirth F, Doppler S, Lahm H, Dreßen M, von Scheidt M, Knoll K, Kessler T, Hengstenberg C, Schunkert H, Nickenig G, Nöthen MM, Bolger AP, Abdelilah-Seyfried S, Samani NJ, Erdmann J, Trenkwalder T, Schumacher J.   +58 more
europepmc   +7 more sources

The Natural History of Bicuspid Aortic Valve Disease. [PDF]

Struct Heart, 2023
The bicuspid aortic valve (BAV) is the most common congenital heart defect with an estimated prevalence of between 0.5% and 2% in the United States, representing up to 6.5 million individuals. Most individuals with BAV will develop valvular and/or aortic complications related to their BAV.
Kusner JJ, Brown JY, Gleason TG, Edelman ER.   +3 more
europepmc   +4 more sources

Bicuspid Aortic Valve Disease [PDF]

Journal of the American College of Cardiology, 2010
Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the BAV can be found in isolation, it is often associated with other congenital cardiac lesions. The most frequent associated finding is dilation of the proximal ascending aorta secondary to abnormalities of the aortic media.
Siu, Samuel C., Silversides, Candice K.
openaire   +5 more sources

TRANSCATHETER AORTIC VALVE REPLACEMENT IN BICUSPID AORTIC VALVE DISEASE [PDF]

Journal of the American College of Cardiology, 2014
BACKGROUND Limited information exists describing the results of transcatheter aortic valve (TAV) replacement in patients with bicuspid aortic valve (BAV) disease (TAV-in-BAV). OBJECTIVES This study sought to evaluate clinical outcomes of a large cohort of patients undergoing TAV-in-BAV.
Mylotte, Darren, Lefevre, Thierry, Søndergaard, Lars, Watanabe, Yusuke, Modine, Thomas, Dvir, Danny, Bosmans, Johan, Tchetche, Didier, Kornowski, Ran, Sinning, Jan-Malte, Thériault-Lauzier, Pascal, O'Sullivan, Crochan J, Barbanti, Marco, Debry, Nicolas, Buithieu, Jean, Codner, Pablo, Dorfmeister, Magdalena, Martucci, Giuseppe, Nickenig, Georg, Wenaweser, Peter, Tamburino, Corrado, Grube, Eberhard, Webb, John G, Windecker, Stephan, Lange, Ruediger, Piazza, Nicolo   +25 more
exaly   +8 more sources

Long-term outcome of bicuspid aortic valve disease. [PDF]

Eur Heart J Cardiovasc Imaging, 2023
Abstract Aims Bicuspid aortic valve (BAV) is a common congenital condition that is frequently associated with aortic stenosis (AS) and aortic regurgitation (AR), as well as aortic aneurysms, but specific outcome data are scarce.
Aschauer J, Zilberszac R, Gleiss A, Colizzi C, Binder T, Bruno P, Laufer G, Massetti M, Gabriel H, Rosenhek R.   +9 more
europepmc   +4 more sources

Hemodynamic Profiles Before and After Surgery in Bicuspid Aortic Valve Disease—A Systematic Review of the Literature [PDF]

Frontiers in Cardiovascular Medicine, 2021
Bicuspid aortic valve (BAV) disease presents a unique management challenge both pre- and post-operatively. 4D flow MRI offers multiple tools for the assessment of the thoracic aorta in aortic valve disease.
Daniel G. W. Cave, Hannah Panayiotou, Malenka M. Bissell   +2 more
doaj   +2 more sources

Bicuspid Aortic Valve Disease: A Comprehensive Review

Cardiology Research and Practice, 2012
Bicuspid aortic valve is the commonest congenital cardiac abnormality in the general population. This paper article will discuss our current knowledge of the anatomy, pathophysiology, genetics, and clinical aspects of bicuspid aortic valve disease.
Ify Mordi, Nikolaos Tzemos
doaj   +4 more sources

Bicuspid Aortic Valve Disease: Classifications, Treatments, and Emerging Transcatheter Paradigms [PDF]

Structural Heart
Bicuspid aortic valve (BAV) is a common congenital valvular malformation, which may lead to early aortic valve disease and bicuspid-associated aortopathy. A novel BAV classification system was recently proposed to coincide with transcatheter aortic valve
Ankur Kalra, MD, Rajiv Das, MB ChB, MD, Mohammad Alkhalil, MD, DPhil, Iryna Dykun, MD, Alessandro Candreva, MD, Omar Jarral, MBBS, PhD, Syed M. Rehman, MBBS, Monil Majmundar, MD, Kunal N. Patel, MD, MPH, Josep Rodes-Cabau, MD, PhD, Michael J. Reardon, MD, Rishi Puri, MBBS, PhD   +11 more
doaj   +2 more sources

Valve morphology and timing of surgery in bicuspid aortic valve disease. [PDF]

Clin Res Cardiol
Abstract Background The anatomy of bicuspid aortic valves (BAV) varies considerably and is broadly classified into two main types: two-sinus and fused BAV. Possible prognostic implications of these two main types remain unclear. This study aimed to assess potential associations between BAV morphology and the timing of
Wulffeld S, Schmiegelow MDS, Oksjoki R, Nielsen DG, Schmiegelow SS, Ngo AT, Raunsø J, Larsen MK, Bruun NE, Procida K.   +9 more
europepmc   +5 more sources

Bicuspid aortic valve associated aortopathy: a genetic disease? [PDF]

Cardiogenetics, 2015
The present paper briefly reviews the literature supporting the pathogenetic importance of hemodynamics in the development of bicuspid aortic valve-associated aortopathy.
Ciro Bancone, Marisa De Feo, Alessandro Della Corte   +2 more
doaj   +5 more sources