Results 161 to 170 of about 213,227 (296)

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Metabolic reprogramming in aortic diseases: insights from metabolomics and therapeutic opportunities. [PDF]

Med Rev (2021)
Liu Y, Zhao L, Zhang C, Ruan X, Yu H, Cao Y, Ju W, Lu H.   +7 more
europepmc   +1 more source

Cardiac computed tomography assessment of congenital aortic diseases: a case series. [PDF]

Eur Heart J Case Rep, 2023
Espinola-Zavaleta N, Armenta-Moreno JI, Silva-Estrada JA, Serrano-Roman J, Espejel-Guzman A, Fernandez-Badillo V, Navarro-Martinez DA, Cano-Zarate R.   +7 more
europepmc   +1 more source

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Applications of Three-Dimensional Printing in the Management of Complex Aortic Diseases. [PDF]

Aorta (Stamford), 2022
Magagna P, Xodo A, Menegolo M, Campana C, Ghiotto L, Salvador L, Grego F.   +6 more
europepmc   +1 more source

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source

Multimodal imaging of acquired aortic diseases: clinical efficacy, comparative analysis, and future perspectives. [PDF]

Int J Cardiovasc Imaging
Li C, Liu C.
europepmc   +1 more source

Long-term outcomes after endovascular aortic treatment in patients with thoracic aortic diseases. [PDF]

J Vasc Bras, 2023
Brandi AC, Dos Santos CA, Brandi JM, Dos Santos MA, Botelho PHH.   +4 more
europepmc   +1 more source

Aortic disease and peripheral artery disease

Journal of Geriatric Cardiology
The Annual Report on Cardiovascular Health and Diseases in China (2022) intricate landscape of car-diovascular health in China. In connection with the previous section, this 10th section of the report offers a comprehensive analysis of aortic disease and peripheral artery disease.
openaire   +2 more sources

From armadillos to sloths: Patterns and variations in xenarthran coronary anatomy

The Anatomical Record, EarlyView.
Abstract Species of the superorder Xenarthra play a vital ecological role in the Neotropics. Despite their evolutionary significance, anatomical studies on their coronary circulation remain scarce. This study investigated the coronary anatomy of 82 hearts from nine Xenarthra species across the Dasypodidae, Myrmecophagidae, and Bradypodidae.
Wilson Viotto‐Souza, André Luiz Quagliatto Santos, Marcelo Abidu‐Figueiredo, Thaís Aparecida Silva, Rodrigo Ananias Barreiros Silva, Paulo de Souza‐Junior   +5 more
wiley   +1 more source