Results 31 to 40 of about 2,421,495 (257)

Nano-Biomaterials for the Delivery of Therapeutic and Monitoring Cues for Aortic Diseases

Frontiers in Bioengineering and Biotechnology, 2020
The aorta is the largest artery in the body, so any diseases or conditions which could cause damage to the aorta would put patients at considerable and life-threatening risk. In the management of aortic diseases, the major treatments include drug therapy,
Shichao Zhu, Shichao Zhu, Kai Zhu, Kai Zhu, Jun Li, Jun Li, Hao Lai, Hao Lai, Chunsheng Wang, Chunsheng Wang   +9 more
doaj   +1 more source

Peripheral Artery Disease and Aortic Disease [PDF]

Global Heart, 2016
We reviewed published MESA (Multi-Ethnic Study of Atherosclerosis) study articles concerning peripheral arterial disease, subclavian stenosis (SS), abdominal aortic calcium (AAC), and thoracic artery calcium (TAC). Important findings include, compared to non-Hispanic whites, lower ankle-brachial index (ABI) and more SS in African Americans, and higher ...
Criqui, Michael H, Aboyans, Victor, Allison, Matthew A, Denenberg, Julie O, Forbang, Nketi, McDermott, Mary M, Wassel, Christina L, Wong, Nathan D   +7 more
openaire   +5 more sources

Safety and effectiveness of the sutureless integrated stented graft prosthesis in an animal model

Heliyon
Background: Prolonged circulatory arrest time is an independent risk factor for postoperative adverse events of type A aortic dissection (TAAD) surgery. Further reduction of the circulatory arrest time is essential to improve surgical outcomes.
Lu Dai, Chenyu Zhou, Liang Zhang, Juntao Qiu, Shen Liu, Jiawei Qiu, Rui Zhao, Enzehua Xie, Jian Song, Cuntao Yu   +9 more
doaj   +1 more source

Protective Effect on Spinal Cord Injury of Prophylactic Cerebrospinal Fluid Drainage in Extensive Aortic Arch Repair for Type A Aortic Dissection: A Retrospective Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cerebrospinal fluid drainage (CSFD) is commonly used to manage spinal cord injury (SCI) after aortic surgery. However, there is still limited evidence regarding its effectiveness in patients with type A aortic dissection undergoing total arch ...
Chenyu Zhou, Bin Hou, Kai Zhang, Shiqi Gao, Fangfang Cao, Yumeng Ji, Enzehua Xie, Jiawei Qiu, Juntao Qiu, Cuntao Yu   +9 more
doaj   +1 more source

aCTA structured reporting of aortic dissection and updated knowledge required by radiologists

Journal of Cardiothoracic Surgery
The development of Computed Tomography Angiography (CTA) has greatly enhanced the diagnosis of aortic dissection (AD). However, there is currently no comprehensive reporting requirement for the diagnosis of AD. Structured reporting templates are becoming
Jinping Li, Hanqing Zhu, Wenhui Li, Zhibo Guo, Hui Wang, Feifei Sun, Kaiwei Lu, Yi Li, Chuanbin Wei, Wenhua Guan   +9 more
doaj   +1 more source

Increased risk for the development of postoperative severe hypoxemia in obese women with acute type a aortic dissection

Journal of Cardiothoracic Surgery, 2019
Background The purpose of this study is to identify the risk factors for postoperative severe hypoxemia after surgery for acute type A aortic dissection.
Ming Gong, Zining Wu, Shijun Xu, Lei Li, Xiaolong Wang, Xinliang Guan, Hongjia Zhang   +6 more
doaj   +1 more source

Novel understanding on thoracic aortic diseases from bioengineering concepts

, 2019
Endovascular treatment modalities have decreased the mortality and morbidity of thoracic aortic diseases considerably in the past decades, due to the effectiveness of such interventions and the minimal invasive character.
Conti M., Romarowski R., Auricchio F., Figueroa C. A., Van Bakel T. M. J., Morganti S., Van Herwaarden J. A., Nauta F. J. H., Trimarchi S., C. Alberto Figueroa, J. A. van Herwaarden, Rodrigo Romarowski, Simone Morganti, Santi Trimarchi, F. J. H. Nauta, F. Auricchio, Michele Conti, T. M. J. van Bakel   +17 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Consumption coagulopathy in acute aortic dissection: principles of management

Journal of Cardiothoracic Surgery, 2017
Background The effect of acute aortic dissection itself on coagulopathy or surgery-related coagulopathy has never been specifically studied. The aim of the present study was to perioperatively describe consumption coagulopathy in patients with acute ...
Yuyong Liu, Lu Han, Jiachen Li, Ming Gong, Hongjia Zhang, Xinliang Guan   +5 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source