Results 51 to 60 of about 315,210 (298)

Modelling mitral valvular dynamics–current trend and future directions [PDF]

open access: yes, 2017
Dysfunction of mitral valve causes morbidity and premature mortality and remains a leading medical problem worldwide. Computational modelling aims to understand the biomechanics of human mitral valve and could lead to the development of new treatment ...
Berry, Colin   +6 more
core   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee   +7 more
wiley   +1 more source

Congenital Abdominal Aortic Aneurysm: A Case Report and Literature Review

open access: yesFrontiers in Pediatrics, 2022
Congenital abdominal aortic aneurysm is a rare disease with unknown etiology, and the common symptoms are abdominal pulsatile mass and pain caused by aneurysm rupture. The disease has a high mortality rate and fewer reports of surgical treatment.
Zhibin Zhou   +4 more
doaj   +1 more source

Material transport in the left ventricle with aortic valve regurgitation

open access: yes, 2018
This experimental in vitro work investigates material transport properties in a model left ventricle in the case of aortic regurgitation, a valvular disease characterized by a leaking aortic valve and consequently double-jet filling within the elastic ...
Di Labbio, Giuseppe   +2 more
core   +1 more source

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity [PDF]

open access: yes, 2014
Background—Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive.
Ait-Oufella, Hafid   +16 more
core   +2 more sources

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Prediction of Turbulent Shear Stresses through Dysfunctional Bileaflet Mechanical Heart Valves using Computational Fluid Dynamics

open access: yes, 2018
There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease.
Gamage, Peshala T.   +2 more
core   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi   +2 more
wiley   +1 more source

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour   +6 more
wiley   +1 more source

Balloon-Assisted Selective Renal Artery Protection in the Endovascular Management of Juxtarenal Aortoiliac Occlusion

open access: yesVascular Specialist International
Purpose: This study aimed to evaluate the feasibility and safety of balloon-assisted selective renal protection during endovascular treatment of juxtarenal aortoiliac occlusive disease (AIOD) and to present a preoperative computed tomography angiography (
Tao Shi, Yongbao Zhang
doaj   +1 more source

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