Results 71 to 80 of about 2,421,495 (257)

Transcatheter Aortic Valve Implantation in Dialysis Patients [PDF]

, 2012
Background/Aims: Transcatheter aortic valve implantation (TAVI) has emerged as a new therapeutic option for high-risk patients. However, dialysis patients were excluded from all previous studies.
Wessely, Matthias, Schoenermarck, Ulf, Rau, Simon, Fischereder, Michael, Steinbeck, Gerhard, Kupatt, Christian, Lange, Philipp   +6 more
core   +1 more source

Clinical research regional vascular changes and aortic dilatation in pediatric patients with bicuspid aortic valve

, 2022
: Background: Bicuspid aortic valve (BAV) is the most common congenital heart disease, often associated with valve dysfunction, coarctation of the aorta, and ascending aorta dilatation.
Franco-Cereceda, Anders, Andelfinger, Gregor, Rumman, Rawan K., Slorach, Cameron, Mertens, Luc, Mital, Seema, Grattan, Michael, Lopez, Carmen, Fan, Steve, Mohamed, Salah A., Dietz, Harry, Hui, Wei, Loeys, Bart, Larios, Guillermo, Rumman, RK, Larios, G, Mohamed, SA, Slorach, C, Franco-Cereceda, A, Fan, S, Loeys, B, Hui, W, Dietz, H, Lopez, C, Guillermo Larios, Luc Mertens, Harry Dietz, Bart Loeys, Steve Fan, Seema Mital, Cameron Slorach, Rawan K. Rumman, Wei Hui, Carmen Lopez, Michael Grattan, Gregor Andelfinger, Salah A. Mohamed, Anders Franco-Cereceda   +37 more
core   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Hereditary Thoracic Aortic Diseases [PDF]

Advances in both imaging techniques and genetics have led to the recognition of a wide variety of aortic anomalies that can be grouped under the term 'hereditary thoracic aortic diseases'.
Elena Bennati, Francesco Bianco, Spaziani Gaia, Valentina Bucciarelli, Gaia Spaziani, Francesca Chiara Surace, Silvia Favilli, Luigi Arcieri, Francesca Girolami, Francesca Bonanni   +9 more
core   +1 more source

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

Advanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong, Chi Cong Nguyen, Hannah Thuy Truong, Kefan Zhu, Adrienne Ji, James Davies, Emanuele Nicotra, Bibhu Sharma, Jingjing Wan, Patrick Pruscino, Shing Wai Wong, Hoang‐Phuong Phan, Phuoc Thien Phan, Nigel H. Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Adult Bicuspid Aortic Valve

, 2020
Bicuspid aortic valve (BAV) is the most common congenital defect of the heart, occurring in 0.5-2% of live births. It is estimated to be responsible for a relevant burden of valvular and vascular disease in the adulthood (bicuspid valvulo-aortopathy ...
F. Lo Presti, A. Della Corte
core  

Dysphagia in an adult tetralogy of fallot with double aortic arch [PDF]

, 2013
Double aortic arch (DAA) is a common vascular ring. It may occur in isolation or coexist with various types of congenital heart disease . The anomaly usually presents in early infancy.
Bhan, Anil, Munesh, Tomar, Pankaj, Bhatiya   +2 more
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source