Results 221 to 230 of about 81,319 (309)

Methodological Considerations in Interpreting Mortality Trends in Aortic Dissection Among Hypertensive Adults. [PDF]

Clin Cardiol
Bibi H, Arif S.
europepmc   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, EarlyView.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Aortic Dissection in a Patient With Fontan Physiology: Complex Emergency Repair and Tailored Coronary Reconstruction. [PDF]

JACC Case Rep
Mourad N, Witvrouwen I, Monagle S, Liu R, Raubenheimer J, Sinclair B, Bashir J, Muhieldin A.   +7 more
europepmc   +1 more source

Transcriptomic and metabolomic analyses reveal that lobeglitazone ameliorates hepatic steatosis in rats concurrent with regulation of mitochondrial pyruvate metabolism

British Journal of Pharmacology, EarlyView.
Background and Purpose Lobeglitazone is a thiazolidinedione and PPARγ agonist that improves metabolic parameters and hepatic steatosis, but its mechanisms are not fully understood. This study investigated the effects of lobeglitazone on hepatic transcriptomic and metabolic profiles in a rat model of obesity and Type 2 diabetes mellitus.
Hyekyung Yang, Su Young Son, Youngmi Song, Hyewon Choi, In‐Gu Do, Choong Hwan Lee, Cheol‐Young Park   +6 more
wiley   +1 more source

Prognostic Value of a Composite Inflammation-Renal Function Score in Type A Aortic Dissection. [PDF]

J Cardiovasc Dev Dis
Zhou RQ, Peng YD, Cai H, Zhang C, Wu QC.
europepmc   +1 more source

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

Cell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia, Man Li, Yanyu Chen, Jialin Chen, Yuting Cui, Xi‐Long Zheng, Jing Yang, Bingzhao Li, Xiaofeng Ma, Miao Liu, Gang Fan, Juan Peng, Xiaoyan Dai, Zhihan Tang   +13 more
wiley   +1 more source

Type-A Aortic Dissection Evading Aortic Dissection Detection Score in Vulnerable Patient: A Case Report. [PDF]

Clin Case Rep
Wehking F, Lewejohann JC, Buerckenmeyer F.   +2 more
europepmc   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

Bilateral Renal Artery Thrombosis With Distal Abdominal Aortic Dissection as the First Presentation of Takayasu Arteritis. [PDF]

Case Rep Nephrol
Thanigasalan M, Rasanayagam M, Selvarajah M.   +2 more
europepmc   +1 more source

Extraperitoneal single‐site robot‐assisted radical prostatectomy with extended pelvic lymph node dissection: technique and experience

BJU International, Volume 135, Issue 4, Page 700-705, April 2025.
Yubo Wang, Mingzhao Li, Kai Yao, Zhuyinjun Zong, Yifan Chang, Yongda Liu, Chao Cai, Fadi Mousa Al Kalailah, Shancheng Ren, Guohua Zeng, Di Gu   +10 more
wiley   +1 more source