Results 111 to 120 of about 1,982,028 (198)

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

Single-stage multidisciplinary management of contiguous infection involving infected abdominal aortic aneurysm and lumbar spondylodiscitis following infective endocarditis

Journal of Vascular Surgery Cases and Innovative Techniques
Infective endocarditis can cause septic embolization and metastatic infections, including infected aortic aneurysm and spondylodiscitis. We report the case of a 77-year-old man with contiguous infection who was successfully treated using a single-stage ...
Jun Iida, MD, PhD, Hisao Harada, MD, Ryoko Arakaki, MD, Tetsuji Inoue, MD, PhD, Seiya Saito, MD, PhD, Mayuko Ouchi, MD, PhD, Yoshio Arai, MD, PhD   +6 more
doaj   +1 more source

In patients with thoracic aortic graft infection, is graft explantation and replacement superior to in situ graft preservation? [PDF]

Interact Cardiovasc Thorac Surg, 2022
Poon SS, George J, Kumar P, Field M.
europepmc   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Extra-Anatomical Bypass Grafting and Latissimus Dorsi Myocutaneous Flap Reconstruction for Post-sternotomy Mediastinitis With Prosthetic Aortic Graft Infection. [PDF]

Cureus, 2021
Kitano D, Matsuo J, Sakakibara S, Oomura A, Osaki T, Okada K, Terashi H.   +6 more
europepmc   +1 more source

Self Made Bovine Pericardial Tube Grafts in Aortic Infection: A European Multicentre Study. [PDF]

OBJECTIVE This study examines outcome and durability of self made bovine pericardial tube grafts in aortic infections of all anatomic locations. METHODS This was a retrospective and prospective international multicentre study. Peri-operative and
Czerny, Martin, Weiss, Salome, Biro, Gabor, Walter, Tim, Lang, Werner, Puttini, Ilaria, Hugas Mallorqui, Maria, Wyss, Thomas R, Wyss, Thomas R., Schmidli, Jürg, Almasi-Sperling, Veronika, Mallorqui, Maria Hugas   +11 more
core   +2 more sources

Occurrence of infections in dogs receiving ciclosporin in a single‐centre UK referral population

Journal of Small Animal Practice, EarlyView.
Objectives The study aimed (a) to describe the occurrence and nature of new infections in dogs receiving oral ciclosporin and (b) to identify any risk factors associated with the development of a new infection whilst receiving ciclosporin. Materials and Methods In this retrospective cohort study, medical records of dogs presented to a private UK ...
S. Dormon, J. Walker, G. Gallow, L. Goonan, T. Sparks, A. Paul   +5 more
wiley   +1 more source

Aortic versus non-aortic cryopreserved allograft and donor-specific outcome: a retrospective observational study

Frontiers in Surgery
IntroductionCryopreserved arterial allografts are an established conduit for vascular reconstruction in patients with vascular graft infection (VGI). Although outcomes after aortic and peripheral implantation have been reported separately, comparative ...
Matthias Buerger, Anna Schneider, Franz Bartholomé, Philipp Pauli, Alexandra Bonietzki, Thorben Michaelis, Melanie Rusch, Grischa Hoffmann, Rene Rusch, Sebastian Kapahnke   +9 more
doaj   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

¹⁸F-Fluorodeoxyglucose PET imaging in aortic graft infection: many more questions than answers. [PDF]

J Nucl Cardiol, 2021
Pucar D, Sadeghi MM.
europepmc   +1 more source