Results 101 to 110 of about 112,522 (335)

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

open access: yesAdvanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu   +11 more
wiley   +1 more source

Multidetector Computed Tomography Angiography Findings of Chronic-Contained Thoracoabdominal Aortic Aneurysm Rupture with Severe Thoracal Vertebral Body Erosion

open access: yesCase Reports in Radiology, 2013
Chronic-contained aortic aneurysm rupture with vertebral erosion is a rare entity with fatal complications. Multidetector computed tomography (CT) angiography is an important diagnostic method for the evaluation of the aortic aneurysms, their ...
Ruken Yuksekkaya   +5 more
doaj   +1 more source

Long term outcomes in men screened for abdominal aortic aneurysm : prospective cohort study [PDF]

open access: yes, 2012
PMID: 22563092 [PubMed - indexed for MEDLINE] PMCID: PMC3344734 Free PMC ArticlePeer reviewedPublisher ...
Duncan, John L   +4 more
core   +2 more sources

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

open access: yesAdvanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu   +9 more
wiley   +1 more source

Patient-specific image-based computer simulation for theprediction of valve morphology and calcium displacement after TAVI with the Medtronic CoreValve and the Edwards SAPIEN valve [PDF]

open access: yes, 2016
AIMS: Our aim was to validate patient-specific software integrating baseline anatomy and biomechanical properties of both the aortic root and valve for the prediction of valve morphology and aortic leaflet calcium displacement after TAVI.
Bosmans, B   +18 more
core   +1 more source

Rupture of the Aortic Valve [PDF]

open access: yesCirculation, 1956
L J, MCCORMACK, W L, PROUDFIT
openaire   +2 more sources

Monocyte‐Differentiation‐Activated Fluorescent “Scout” Probe for Precise in Vivo Detection of Vulnerable Plaque

open access: yesAdvanced Science, EarlyView.
An innovative monocyte‐differentiation‐activated fluorescent “scout” probe (MDAF) leverages the inherent chemotaxis of monocytes toward vulnerable plaques (VAP) to enable efficient targeted delivery while achieving spatiotemporally controllable activation of its AIE fluorescent signals with the dynamic differentiation of monocytes, providing an ...
Zechuan Li   +15 more
wiley   +1 more source

Aortic Coarctation: Recent Developments in Experimental and Computational Methods to Assess Treatments for this Simple Condition [PDF]

open access: yes, 2010
Coarctation of the aorta (CoA) is often considered a relatively simple disease, but long-term outcomes suggest otherwise as life expectancies are decades less than in the average population and substantial morbidity often exists.
Feinstein, Jeffrey A.   +2 more
core   +2 more sources

Ruptured abdominal aortic aneurysms

open access: yesJournal of British Surgery, 1978
Abstract The results of operation in 76 patients with a ruptured abdominal aortic aneurysm are presented with an analysis of the cause of operative death. Overall mortality was 58 per cent and preoperative hypotension significantly increased mortality; deterioration while awaiting operation made a successful outcome particularly unlikely.
M J, Butler, A D, Chant, J H, Webster
openaire   +2 more sources

12‐HETE Is an Endogenous Modulator of BLT2 Triggering Vascular Degeneration, Dissection, and Rupture

open access: yesAdvanced Science, EarlyView.
In thoracic aortic dissection (TAD), elevated levels of the arachidonic acid metabolite 12‐HETE, produced by macrophage‐specific 12/15‐lipoxygenase (12/15‐LOX), bind to the BLT2 receptor on vascular cells. This activates the NOX‐1/ROS/NF‐κB signaling pathway, leading to IL‐6 release.
Yuyu Li   +13 more
wiley   +1 more source

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