Results 121 to 130 of about 493,183 (300)

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Look past the bleed! A case of non-traumatic thoracic aortic pseudoaneurysm presenting as haemoptysis

European Journal of Case Reports in Internal Medicine
Introduction: Aortic pseudoaneurysms are a type of contained rupture where most of the aortic wall is breached, leaving only a thin rim of the remaining wall or adventitia to hold the blood.
Fawwad Ansari, Bilal Hamid, Fahad Mushtaq, Mubashira Aftab, Zainab Kiyani, Benjamin Lloyd, Muhammad Umer Riaz Gondal   +6 more
doaj   +1 more source

MicroRNA‐Mediated Autophagy and Cardiovascular Diseases: Exploring the Crossroads of Atherosclerosis and Beyond

Journal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the dynamic bidirectional crosstalk between microRNA biogenesis and autophagy, which serves as a critical regulatory axis in cardiovascular homeostasis. We highlight how specific miRNAs modulate autophagic flux to mitigate vascular inflammation and plaque instability, while concurrently, the autophagic machinery ...
Sepehr Ebrahimi‐Dehkordi, Amir Hossein Barjasteh, Aida Zarei, Sina Bazmi, Sarah Vaseghi, Sara Ashna, Amirreza Solati, Ali Yousefzadeh, Bita Safarzadeh Nasrabad, Zahra Mohammadi, Hamed Haddad Kashani, Mohammad Hossein Pourhanifeh   +11 more
wiley   +1 more source

Case Report: Rupture of the cardiac free wall after myocardial infarction confirmed by aortic computed tomography angiography

Frontiers in Cardiovascular Medicine
IntroductionFree wall rupture is a rare complication of myocardial infarction, occurring as early as a few hours after myocardial infarction. It usually happens after transmural myocardial infarction and has a very high mortality rate.
Jie Liu, Weiqing Chen, Zihan Li, Nan Liu, Cuiying Mao   +4 more
doaj   +1 more source

Case of sudden death following rupture of thoracic aortic aneurysm during “a manual therapy” procedure in the spinal area

, 2015
The reported case concerns the rupture of an aneurysm located in the descending part of the thoracic aorta during the procedure of the so-called “spinal adjustment” performed by a chiropractor. A 45-year-old patient with no significant medical history of
Agnieszka Dąbkowska, Aleksandra Kaczorowska   +1 more
core   +1 more source

Study of Risk Factors and Image Findings of Isolated Abdominal Incidentally Detected Aortic Dissection

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 429-435, March/April 2025.
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi, Hidenori Onishi, Koji Maeno, Masaya Nakagaichi, Ikue Tsukushi, Youichi Kitano, Yoshitaka Makino, Hiroyuki Hayashi, Hidekazu Terasawa, Hiroko Kabuto, Toshihiro Misawa, Taku Sanada, Azusa Hisada, Kazuo Notsumata, Kazuhiro Okafuji, Osamu Yamamura   +15 more
wiley   +1 more source

Prevention of rupture of abdominal aortic aneurysm

, 2010
Two thirds of patients with an abdominal aortic aneurysm (AAA) have relevant coronary artery disease (CAD). AAAs are prevalent in up to 16% of smokers with CAD. General screening of AAA is controversial.
Meier, B, Widmer, M K, Carrel, T, Novak, J, Schmidli, J, Savolainen, H, Dick, F   +6 more
core  

RCC prolapse causing Aortic regurgitation in a restrictive VSD [PDF]

, 2015
The incidence of aortic right coronary cusp (RCC) prolapse in outlet ventricular septal defect (VSD) is reported at 5%- 16%. Detection of RCC prolapse is critical in patients with outlet VSD because this complication may cause permanent aortic ...
Rabbani, Zeinab, Abqari, Shaad, Meshram, H. S., Gupta, A.   +3 more
core  

Factors promoting rupture of abdominal aortic aneurysms

, 2005
peer reviewedThe risk for rupture of an abdominal aortic aneurysm is widely believed to be related to its maximum diameter. Rupture occurs at the site of maximum wall stress, when it exceeds the tensile strength of the aortic wall.
Van Damme, Hendrik, Limet, Raymond, Sakalihasan, Natzi   +2 more
core   +1 more source

FOXC1: A Key Transcription Factor of VSMC‐Derived Foam Cell Formation in Atherosclerotic Plaque Instability

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian, Xue‐Ling Li, Li‐Hong Wang, Wei Yang, Yu Jiang   +4 more
wiley   +1 more source