Results 131 to 140 of about 65,401 (262)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Thoracic aortic rupture in a patient with repeated oral fluoroquinolone administration. [PDF]

J Surg Case Rep
Narita M, Akasaka N, Shirakura K, Fukuta H, Nakatsu T, Kamiya H.   +5 more
europepmc   +1 more source

Aortic Rupture and Hemorrhagic Shock After Percutaneous Retrieval of an Embolized Left Atrial Appendage Occluder. [PDF]

JACC Case Rep, 2022
Mastrangelo A, Galli S, Montorsi P, Bartorelli AL.   +3 more
europepmc   +1 more source

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source

Semaglutide Prevents Aortic Rupture and Dissection in the Angiotensin II Mouse Model. [PDF]

Biomedicines
Balboa Ramilo A, Mani K, Wanhainen A, Lodén H, Nilsson A, Andrén PE, Friederich-Persson M, Wågsäter D.   +7 more
europepmc   +1 more source

Thoracic aortic rupture due to airbag deployment. [PDF]

World J Emerg Med, 2021
Plodr M, Safr M, Novak I.
europepmc   +1 more source

Aortic rupture

, 2021
openaire   +1 more source

RUPTURE OF AORTIC ANEURYSMS INTO THE GUT [PDF]

Heart, 1959
G A, GRESHAM, H R, JOHNSON
openaire   +2 more sources

Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose CGRP is a potent, clinically relevant coronary vasodilator known to play a role in cardioprotection. Here, we investigated the precise intracellular signalling pathways leading to vasodilation in small coronary arteries.
Lucy A. Donovan, JinHeng Lin, Milind Khashu, Christopher J. Garland, Kim A. Dora   +4 more
wiley   +1 more source

<i>Brucella</i> Infection Associated with Abdominal Aortic Rupture and Retroperitoneal Hematoma: A Case Report. [PDF]

J Inflamm Res
Shao T, Chen N, Sun Q, Sheng P.
europepmc   +1 more source