Results 141 to 150 of about 65,401 (262)

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Kyphoscoliotic Ehlers-Danlos syndrome associated with superior mesenteric artery aneurysm and abdominal aortic rupture: a case report. [PDF]

Front Pediatr
Li J, Liu K, Zhu X, Xu Y, Xu L, Chi R, Zhu Y.   +6 more
europepmc   +1 more source

Ruptured Abdonimal Aortic Aneurysms

Annals of Surgery, 1973
H B, Shumacker, D L, Barnes, H, King
openaire   +3 more sources

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

Cell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia, Man Li, Yanyu Chen, Jialin Chen, Yuting Cui, Xi‐Long Zheng, Jing Yang, Bingzhao Li, Xiaofeng Ma, Miao Liu, Gang Fan, Juan Peng, Xiaoyan Dai, Zhihan Tang   +13 more
wiley   +1 more source

Fatal Aortic Rupture at Term Pregnancy Caused by Vascular Ehlers-Danlos Syndrome Diagnosed by Postmortem Genetic Testing Using Formalin-Fixed, Paraffin-Embedded Tissue. [PDF]

J Obstet Gynaecol Res
Tadakawa M, Yamaguchi T, Tomita H, Mochii N, Hamada H, Tsubata M, Kosho T, Aoki Y, Saito M.   +8 more
europepmc   +1 more source

Proteomic Profiling Captures Residual Cardiovascular Risk Beyond the PREVENT Model in Individuals With Cardiovascular–Kidney–Metabolic Syndrome Stages 2–3

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Cardiovascular–kidney–metabolic (CKM) syndrome reflects complex pathobiological interactions among metabolic disorders, kidney injury, and cardiovascular disease (CVD). Stages 2 and 3 represent critical phases of disease progression characterised by high pathological heterogeneity.
Xuefei Han, Jiacheng Ding, Jingqian Li, Yiyin Gao, Yunqian Li   +4 more
wiley   +1 more source

Aortic rupture from MSSA aortitis in a healthy 21-year-old: a case report. [PDF]

BMC Infect Dis
Kinzinger J, Horke K, Schmoeckel M, Wassilowsky D.   +3 more
europepmc   +1 more source

The susceptibility of the aortic root: porcine aortic rupture testing under cardiopulmonary bypass. [PDF]

J Cardiothorac Surg, 2021
Surman TL, Abrahams JM, Manavis J, Finnie J, Christou C, Williams GK, Walls A, Frantzis P, Adams M, Edwards J, Worthington MG, Beltrame J.   +11 more
europepmc   +1 more source

Nonhuman Pedagogical Relations: Towards Conceptual Limits

Educational Theory, EarlyView.
Abstract This article considers the pedagogical relation as a relation to a nonhuman educator, wherein the educatee is a member of the Homo sapiens species. My aim is to clarify the extent to which a nonhuman‐human relation can be understood as pedagogical.
Silas C. Krabbe
wiley   +1 more source

A case of descending aortic rupture and aortoesophageal fistula secondary to fish bone-induced esophageal perforation. [PDF]

JTCVS Tech
Bungo M, Watanabe KI, Teshima Y, Sakashita Y, Uemura H, Tanaka H, Yamamura M, Sakaguchi T.   +7 more
europepmc   +1 more source