Results 161 to 170 of about 493,183 (300)

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

open access: yesCell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia   +13 more
wiley   +1 more source

Aortic diameter >or = 5.5 cm is not a good predictor of type A aortic dissection: observations from the International Registry of Acute Aortic Dissection (IRAD).

open access: yes, 2007
BACKGROUND: Studies of aortic aneurysm patients have shown that the risk of rupture increases with aortic size. However, few studies of acute aortic dissection patients and aortic size exist.
Isselbacher EM   +15 more
core  

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding   +4 more
wiley   +1 more source

Nonhuman Pedagogical Relations: Towards Conceptual Limits

open access: yesEducational Theory, EarlyView.
Abstract This article considers the pedagogical relation as a relation to a nonhuman educator, wherein the educatee is a member of the Homo sapiens species. My aim is to clarify the extent to which a nonhuman‐human relation can be understood as pedagogical.
Silas C. Krabbe
wiley   +1 more source

Thoracic aortic rupture in a patient with repeated oral fluoroquinolone administration. [PDF]

open access: yesJ Surg Case Rep
Narita M   +5 more
europepmc   +1 more source

Ruptured abdominal aortic aneurysms.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1998
Click on the link to view.
openaire   +2 more sources

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