Results 91 to 100 of about 796,036 (401)

Congenital aortic stenosis due to unicuspid unicommissural aortic valve: a case report

open access: yesJournal of Cardiothoracic Surgery, 2018
Background Unicuspid unicommissural aortic valve is an extremely rare congenital anomaly that usually presents in adulthood but can rarely present in infancy.
Arnar B. Ingason   +2 more
doaj   +1 more source

Dynamic simulation of aortic valve stenosis using a lumped parameter cardiovascular system model with flow regime dependent valve pressure loss characteristics [PDF]

open access: yesarXiv, 2022
Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and obstructive lesions on the valve body can assist clinicians in preparing personalised treatments.
arxiv  

An echocardiographic comparison of sutureless and conventional aortic valve replacement : a matched case-control study [PDF]

open access: yes, 2018
Background: Patients at a high operative risk for conventional aortic valve replacement (AVR) may be offered sutureless valve implantation. Sutureless valves resemble conventional valves but incorporate an anchoring mechanism without using annular ...
Camilleri, Liberato   +6 more
core   +1 more source

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao   +15 more
wiley   +1 more source

Survival benefit of overweight patients undergoing MitraClip® procedure in comparison to normal‐weight patients

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1236-1245, December 2022., 2022
Long‐term survival stratified for weight classes illustrated by Hazard plot for patients treated with MitraClip® implantation stratified for weight classes. Association of weight class compared to normal‐weight with long‐term survival (adjusted for Logistic EuroScore).
Karsten Keller   +12 more
wiley   +1 more source

ProtoASNet: Dynamic Prototypes for Inherently Interpretable and Uncertainty-Aware Aortic Stenosis Classification in Echocardiography [PDF]

open access: yesarXiv, 2023
Aortic stenosis (AS) is a common heart valve disease that requires accurate and timely diagnosis for appropriate treatment. Most current automatic AS severity detection methods rely on black-box models with a low level of trustworthiness, which hinders clinical adoption. To address this issue, we propose ProtoASNet, a prototypical network that directly
arxiv  

Unveiling transthyretin cardiac amyloidosis and its predictors among elderly patients with severe aortic stenosis undergoing transcatheter aortic valve replacement

open access: yesEuropean Heart Journal, 2017
Aims Transthyretin cardiac amyloidosis (ATTR-CA) has been reported in patients with aortic stenosis (AS) but its prevalence and phenotype are not known.
Adam Castaño   +15 more
semanticscholar   +1 more source

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

open access: yesAdvanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du   +9 more
wiley   +1 more source

Analysis of atherosclerotic plaque distribution in the carotid artery

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1272-1276, December 2022., 2022
Abstract Background The present study was designed to investigate the hypothesis that the outer wall at the carotid bifurcation is the most common area of atherosclerotic plaque deposition due to the low shear stress. Hypothesis We hypothesized that the most common site of arteriosclerosis in carotid arteries is different in the early and late stages ...
Shin‐Seok Yang   +2 more
wiley   +1 more source

Transcatheter Aortic Valve Implantation in Heart Failure Patients with Non-Severe Aortic Valve Stenosis

open access: yesSciMedicine Journal, 2022
Introduction: aortic stenosis (AS) increases the afterload on the left ventricle, leading to structural changes in the heart muscle and gradual progression to heart failure (HF).
Amr Elkammash
doaj   +1 more source

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