Results 11 to 20 of about 830,243 (383)
Calcific aortic stenosis [PDF]
Nature Reviews Disease Primers, 2016 Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed countries. It is characterized by progressive fibro-calcific remodelling and thickening of the aortic valve leaflets that, over years, evolve to cause severe obstruction to cardiac outflow.
Marie-Annick Clavel +6 more
openaire +4 more sources
Moderate Aortic Stenosis in Patients With Heart Failure
Korean Circulation Journal, 2022 Author's summary Moderate aortic stenosis with concomitant heart failure portends a significantly worse prognosis in both preserved and reduced left ventricular ejection fraction.
V. Truong +6 more
semanticscholar +1 more source
European Heart Journal, 2022 Graphical Abstract Graphical abstract Key points from the 2022 Lp(a) consensus statement. Current evidence demonstrates a causal continuous association in different ethnicities between Lp(a) concentration and cardiovascular outcomes including aortic ...
F. Kronenberg +21 more
semanticscholar +1 more source
Cardiac amyloidosis and aortic stenosis: a state-of-the-art review
European Heart Journal Open, 2023 Cardiac amyloidosis is caused by the extracellular deposition of amyloid fibrils in the heart, involving not only the myocardium but also any cardiovascular structure.
Vikash Jaiswal +14 more
semanticscholar +1 more source
Circulation, 2021 Background: Surgical aortic valve replacement (SAVR) represents a class I indication in symptomatic patients with severe aortic stenosis (AS). However, indications for early SAVR in asymptomatic patients with severe AS and normal left ventricular ...
M. Banovic +16 more
semanticscholar +1 more source
Effect of Denosumab or Alendronic Acid on the Progression of Aortic Stenosis
Circulation, 2021 Supplemental Digital Content is available in the text. Background: Valvular calcification is central to the pathogenesis and progression of aortic stenosis, with preclinical and observational studies suggesting that bone turnover and osteoblastic ...
T. Pawade +22 more
semanticscholar +1 more source
Journal of the American Medical Association (JAMA), 2021 Importance There are limited data on outcomes of transcatheter aortic valve replacement (TAVR) for bicuspid aortic stenosis in patients at low surgical risk.
R. Makkar +16 more
semanticscholar +1 more source
Contrast-enhanced computed tomography assessment of aortic stenosis
Heart, 2021 Objectives Non-contrast CT aortic valve calcium scoring ignores the contribution of valvular fibrosis in aortic stenosis. We assessed aortic valve calcific and non-calcific disease using contrast-enhanced CT.
T. Cartlidge +17 more
semanticscholar +1 more source
Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis.
New England Journal of Medicine, 2020 BACKGROUND The timing and indications for surgical intervention in asymptomatic patients with severe aortic stenosis remain controversial. METHODS In a multicenter trial, we randomly assigned 145 asymptomatic patients with very severe aortic stenosis ...
D. Kang +12 more
semanticscholar +1 more source
Echo Research and Practice, 2021 The guideline provides a practical step-by-step guide in order to facilitate high-quality echocardiographic studies of patients with aortic stenosis. In addition, it addresses commonly encountered yet challenging clinical scenarios and covers the use of ...
L. Ring +10 more
semanticscholar +1 more source