Results 41 to 50 of about 133,767 (311)

Quadrivalvular Involvement in Rheumatic Heart Disease: A Rare Case Report

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2022
Four-valve involvement (mitral, aortic, tricuspid, and pulmonary) in rheumatic heart disease (RHD) is an exceedingly rare entity. We report the case of a 24-year-old male, a known case of RHD, who presented with dyspnea and presyncope for 2 months.
C M Satvic, Arnab Ghosh Chaudhury, Lachikarathman Devegowda, Prabhavathi Bhat, C N Manjunath   +4 more
doaj   +1 more source

Statins in Aortic Stenosis

Current Pharmaceutical Design, 2018
Calcific aortic stenosis (AS) is the most common form of valvular heart disease in Europe and North America. It is a progressive disease with a prolonged period of asymptomatic latency which eventually leads to critical left ventricular outflow tract obstruction necessitating surgical replacement of the valve.
Norrington, K., Androulakis, E., Oikonomou, E., Vogiatzi, G., Tousoulis, D.   +4 more
openaire   +3 more sources

Multimodality Imaging to Explore Sex Differences in Aortic Stenosis [PDF]

, 2022
The aim of this article is to review sex differences in aortic stenosis (AS) assessed with multimodality imaging. Echocardiography remains the mainstay imaging technique to diagnose AS and provides important insights into the differences between men and ...
Singh, G.K., Victoria Delgado, Gurpreet K Singh, Delgado, V.   +3 more
core   +1 more source

Valvular Aortic Stenosis: A Proteomic Insight [PDF]

, 2010
Calcified aortic valve disease is a slowly progressive disorder that ranges from mild valve thickening with no obstruction of blood flow, known as aortic sclerosis, to severe calcification with impaired leaflet motion or aortic stenosis.
Lopez-Almodovar, Luis, Cuesta, Fernando de La, Fernando Vivanco, Martin-Rojas, Tatiana, Luis F. Lopez-Almodovar, Tatiana Martin-Rojas, Darde, Veronica, Barderas, Maria, Fernando de la Cuesta, Barroso, Gemma, Maria G. Barderas, Veronica M. Darde, Luis R. Padial, Gemma Barroso, Gloria Alvarez-Llamas, Gil Dones, Félix, Vivanco, Fernando, Felix Gil-Dones, Juarez-Tosina, Rocio, Padial, Luis, Álvarez Llamas, Gloria, Rocio Juarez-Tosina   +21 more
core   +1 more source

Prosthetic Aortic Valve Stenosis in End-Stage Renal Failure

International Journal of Nephrology, 2011
Although renal failure is one of the known comorbidities associated with rapid progression of aortic stenosis, it is unclear whether hemodialysis alters the progression of prosthetic aortic valve stenosis.
Michael Mao, Mirelle El Ters, Sunil Mankad, Mira Keddis, Soon Park, Qi Qian   +5 more
doaj   +1 more source

PROGRESSION OF AORTIC STENOSIS IN THE ELDERLY DETECTED BY NONINVASIVE METHODS [PDF]

, 1988
One hundred eighty consecutive male patients, mean age of 64.6 years, who were referred to cardiac catheterization for the evaluation of aortic stenosis (AS), were studied using a noninvasive scoring system. The system is based upon 7 variables including:
Toshihiko, TAKAMOTO, Koichi, TANIGUCHI, Masao, NITTA   +2 more
core   +2 more sources

Calcific aortic stenosis [PDF]

Nature Reviews Disease Primers, 2016
Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed countries. It is characterized by progressive fibro-calcific remodelling and thickening of the aortic valve leaflets that, over years, evolve to cause severe obstruction to cardiac outflow.
Lindman, Brian R., Clavel, Marie-Annick, Mathieu, Patrick, Iung, Bernard, Lancellotti, Patrizio, Otto, Catherine M., Pibarot, Philippe   +6 more
openaire   +5 more sources

Acquired Supravalvular Aortic Stenosis: Review of a Rare Conundrum with Diverse Etiologies

Indian Journal of Clinical Cardiology
Background Supravalvular aortic stenosis is a rare form of left ventricular outflow tract obstruction. Classically, supravalvular aortic stenosis occurs secondary to elastin arteriopathy, in association with Williams–Beuren syndrome, or as non-syndromic ...
Sandhya S, Lakshmi Bhuvaneswaran Kartha, P Senthilnathan, Sahitya Mandava, Anoop George Alex, Oommen K George, Gayathri Bhuvaneswaran Kartha   +6 more
doaj   +1 more source

Classical supravalvar aortic stenosis and peripheral pulmonary stenosis [PDF]

, 2014
Supravalvar aortic stenosis as well as peripheral pulmonary stenosis are rare forms of congenital heart disease, which occur, however, relatively frequently in association.
Ramakrishnan, S., Gupta, S.K., Kahr, P.C., Kothari, Shyam S.   +3 more
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source