Results 61 to 70 of about 133,355 (312)

Myocardial extracellular volume quantification by computed tomography predicts outcomes in patients with severe aortic stenosis.

PLoS ONE, 2021
BackgroundThe extent of myocardial fibrosis in patients with severe aortic stenosis might have an important prognostic value. Non-invasive imaging to quantify myocardial fibrosis by measuring extracellular volume fraction might have an important clinical
Yoav Hammer, Yeela Talmor-Barkan, Aryeh Abelow, Katia Orvin, Yaron Aviv, Noam Bar, Amos Levi, Uri Landes, Gideon Shafir, Alon Barsheshet, Hana Vaknin-Assa, Alexander Sagie, Ran Kornowski, Ashraf Hamdan   +13 more
doaj   +1 more source

Emergency treatment of acute decompensated critical aortic stenosis with transcatheter aortic valve implantation

, 2020
Transcatheter aortic valve implantation (TAVI) is relatively contraindicated in the bicuspid aortic valve, and to our knowledge has not been tried where the true native annulus is of a size far in excess of current device capabilities.
Singh, Kuljit, Win, Kyi TH, Camuglia, Anthony, Provenzano, Sylvio   +3 more
core   +1 more source

A Novel Splice Variant in ERGIC1 Causes Arthrogryposis Multiplex Congenita—Characterization Using Urine‐Derived Cells

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr, Paul McKay, Juliana Marulanda, Zenghui Wu, Reggie Hamdy, Sena Tavukcu, Noémi Dahan‐Oliel, Frank Rauch   +7 more
wiley   +1 more source

Williams-Beuren syndrome: cardiovascular abnormalities in 20 patients diagnosed with fluorescence in situ hybridization

Arquivos Brasileiros de Cardiologia, 2003
OBJECTIVE: To evaluate the cardiovascular findings and clinical follow-up of patients with Williams-Beuren syndrome. METHODS: We studied 20 patients (11 males, mean age at diagnosis: 5.9 years old), assessed for cardiovascular abnormalities with ...
Sofia Mizuho Miura Sugayama, Regina Lúcia Moisés, Jaqueline Wagënfur, Nana Miura Ikari, Kikue Terada Abe, Cláudio Leone, Clóvis Artur Almeida da Silva, Maria de Lourdes Lopes Ferrari Chauffaille, Ae Kim Chong   +8 more
doaj   +1 more source

Counting the cost of premature mortality with progressively worse aortic stenosis in Australia: A clinical cohort study [PDF]

, 2022
Background: Aortic stenosis is the most common cardiac valve disorder requiring clinical management. However, there is little evidence on the societal cost of progressive aortic stenosis.
Stewart, Simon, Afoakwah, C, Chan, Yih-Kai, Strom, JB, Chan, YK, Strange, GA, Playford, D, Strom, Jordan B., Strange, Geoffrey A., Playford, David, Strange, Geoffrey A, Strom, Jordan B, Afoakwah, Clifford, Stewart, S   +13 more
core   +1 more source

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll, Yves Alembik, Marie‐Paule Roth   +2 more
wiley   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

Genetic Polymorphisms, Plasma Levels of Lipoprotein (A) and its Possible Links with Degenerative Aortic Stenosis [PDF]

Journal of Biomedical & Clinical Research, 2016
Degenerative aortic stenosis is the second most common acquired valvular heart disease in adults (after mitral insufficiency) and the second most common cause for cardiac surgery (after coronary heart disease).
Vesela Tomova, Tihomir Rashev, Milena Atanasova   +2 more
doaj   +3 more sources

Mechanisms of aortic stenosis [PDF]

Journal of Cardiology, 2018
The pathobiology of degenerative aortic valve stenosis (AS) is complex and involves multiple features such as fibrosis, inflammation, oxidative stress, angiogenesis, hemorrhage, and osteogenic differentiation. We summarize the mechanism of valve calcification and angiogenesis which is necessary for calcifying processes.
Hirokuni, Akahori, Takeshi, Tsujino, Tohru, Masuyama, Masaharu, Ishihara   +3 more
openaire   +2 more sources

Comparative evaluation of left ventricular mass regression after aortic valve replacement: a prospective randomized analysis

, 2011
Background: We assessed the hemodynamic performance of various prostheses and the clinical outcomes after aortic valve replacement, in different age groups.
Wood Jeffrey P, Doss, Mirko, Moritz Anton, Arndt H Kiessling, Mirko Doss, Kiessling, Arndt Holger, Anton Moritz, Jeffrey P Wood, Wood, Jeffrey P., Moritz, Anton, Doss Mirko, Kiessling Arndt H   +11 more
core   +1 more source