Results 61 to 70 of about 406,657 (306)

Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI

open access: yesAdvanced Science, EarlyView.
ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia   +7 more
wiley   +1 more source

Non-linear finite element analyses of the aortic heart valve [PDF]

open access: yes, 2004
Includes bibliographical references.Finite element models of the aortic heart valve have been successfully used in the past to gain insight into the mechanics of the valve and to aid in understanding of valve failure.
Koch, Thorsten M
core   +1 more source

LES of additive and non-additive pulsatile flows in a model arterial stenosis [PDF]

open access: yes, 2010
Transition of additive and non-additive pulsatile flows through a simple 3D model of arterial stenosis is investigated by using a large eddy simulation (LES) technique. We find in both the pulsatile cases that the interaction of the two shear layers, one
Molla, M.M., Roditi, G., Paul, M.
core   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

open access: yesAdvanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang   +10 more
wiley   +1 more source

Successful percutaneous balloon dilatation of supravalvular aortic membrane

open access: yesHeart Views, 2019
Supravalvular aortic stenosis is the least common type of left ventricular outflow tract obstruction. Primary balloon dilatation of membranous supravalvular aortic stenosis was performed in a 10-year-old male child with a remarkable reduction in systolic
Gurkirat Singh   +3 more
doaj   +1 more source

Multimodality Imaging to Explore Sex Differences in Aortic Stenosis [PDF]

open access: yes, 2022
The aim of this article is to review sex differences in aortic stenosis (AS) assessed with multimodality imaging. Echocardiography remains the mainstay imaging technique to diagnose AS and provides important insights into the differences between men and ...
Singh, G.K.   +3 more
core   +1 more source

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

open access: yesAdvanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li   +12 more
wiley   +1 more source

Lipoprotein(a) in patients with aortic stenosis: Insights from cardiovascular magnetic resonance.

open access: yesPLoS ONE, 2017
BackgroundAortic stenosis is the most common age-related valvular pathology. Patients with aortic stenosis and myocardial fibrosis have worse outcome but the underlying mechanism is unclear.
Vassilios S Vassiliou   +19 more
doaj   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

open access: yesAdvanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian   +13 more
wiley   +1 more source

Galectin-3 as a novel biotarget in cardiovascular alterations associated to development of severe aortic stenosis

open access: yesAnales del Sistema Sanitario de Navarra, 2019
Aortic stenosis is one of the most common heart valve diseases, as well as one of the most common causes of heart failure in the elderly. Currently, there are no medical therapies to prevent or slow the progression of the disease.
V. Arrieta   +4 more
doaj   +1 more source

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