Results 41 to 50 of about 27,739 (267)

Transcatheter aortic valve implantation (TAVI) with concomitant cerebral and coronary artery occlusion: A case report

IHJ Cardiovascular Case Reports, 2022
Aortic valve stenosis is a common valvular problem in the aging population. Transcatheter aortic valve implantation (TAVI) is a popular treatment alternative to surgical aortic valve replacement for frail elderly individuals with symptomatic severe ...
Viveka Kumar, Pradipta Kumar Nayak, Mitendra Singh Yadav, Sangeeta Dhir   +3 more
doaj  

Ideal Cardiovascular Health and the Prevalence and Severity of Aortic Stenosis in Elderly Patients

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundThe relationship between ideal cardiovascular health reflected in the cardiovascular health score (CVHS) and valvular heart disease is not known.
Morten Sengeløv, Susan Cheng, Tor Biering‐Sørensen, Kunihiro Matsushita, Suma Konety, Scott D. Solomon, Aaron R. Folsom, Amil M. Shah   +7 more
doaj   +1 more source

Dynamic simulation of aortic valve stenosis using a lumped parameter cardiovascular system model with flow regime dependent valve pressure loss characteristics [PDF]

arXiv, 2022
Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and obstructive lesions on the valve body can assist clinicians in preparing personalised treatments.
arxiv  

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source

ProtoASNet: Dynamic Prototypes for Inherently Interpretable and Uncertainty-Aware Aortic Stenosis Classification in Echocardiography [PDF]

arXiv, 2023
Aortic stenosis (AS) is a common heart valve disease that requires accurate and timely diagnosis for appropriate treatment. Most current automatic AS severity detection methods rely on black-box models with a low level of trustworthiness, which hinders clinical adoption. To address this issue, we propose ProtoASNet, a prototypical network that directly
arxiv  

Calcific aortic stenosis [PDF]

Nature Reviews Disease Primers, 2016
Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed countries. It is characterized by progressive fibro-calcific remodelling and thickening of the aortic valve leaflets that, over years, evolve to cause severe obstruction to cardiac outflow.
Marie-Annick Clavel, Patrick Mathieu, Philippe Pibarot, Patrizio Lancellotti, Brian R. Lindman, Bernard Iung, Catherine M Otto   +6 more
openaire   +3 more sources

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

Myocardial extracellular volume quantification by computed tomography predicts outcomes in patients with severe aortic stenosis.

PLoS ONE, 2021
BackgroundThe extent of myocardial fibrosis in patients with severe aortic stenosis might have an important prognostic value. Non-invasive imaging to quantify myocardial fibrosis by measuring extracellular volume fraction might have an important clinical
Yoav Hammer, Yeela Talmor-Barkan, Aryeh Abelow, Katia Orvin, Yaron Aviv, Noam Bar, Amos Levi, Uri Landes, Gideon Shafir, Alon Barsheshet, Hana Vaknin-Assa, Alexander Sagie, Ran Kornowski, Ashraf Hamdan   +13 more
doaj   +1 more source

A New Semi-supervised Learning Benchmark for Classifying View and Diagnosing Aortic Stenosis from Echocardiograms [PDF]

arXiv, 2021
Semi-supervised image classification has shown substantial progress in learning from limited labeled data, but recent advances remain largely untested for clinical applications. Motivated by the urgent need to improve timely diagnosis of life-threatening heart conditions, especially aortic stenosis, we develop a benchmark dataset to assess semi ...
arxiv  

Endothelial TRIM35‐Regulated MMP10 Release Exacerbates Calcification of Vascular Grafts

Advanced Science, Volume 12, Issue 11, March 20, 2025.
Arterial bypass graft is routinely used for the patients with coronary artery infarction, but is limited by progressive vascular restenosis and occlusion occurs, in which vascular calcification is a key issue. Endothelial TRIM35 can protect the isograft vascular from calcification by activating RelB ubiquitination that inhibits MMP10 secretion ...
Yiming Leng, Wei Wang, Jun Lu, Jingyuan Chen, Xuliang Chen, Yalan Li, Jie Wang, Yuanyuan Liu, Qian Tan, Wenjing Yang, Youxiang Jiang, Peiyuan Huang, Jingjing Cai, Hong Yuan, Liang Weng, Qingbo Xu, Yao Lu   +16 more
wiley   +1 more source