Results 81 to 90 of about 830,243 (383)

Survival Outcomes of Esophageal Squamous Cell Carcinoma Patients Who Underwent Salvage Esophagectomy: A Literature Review and Results From Two High‐Volume Centers

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to investigate survival outcomes, the efficacy of lymph node (LN) dissection, and recurrence patterns in 69 patients who underwent R0 salvage surgery for esophageal squamous cell carcinoma. Of note, abdominal LN metastases had a negative impact on survival in our series.
Kotaro Sugawara, Koichi Yagi, Takashi Fukuda, Shoh Yajima, Daiji Oka, Yoshiyuki Miwa, Shuichiro Oya, Asami Okamoto, Raito Asaoka, Yoshifumi Baba   +9 more
wiley   +1 more source

Truncating Variants in RREB1 Cause a Novel RASopathy Syndrome of Congenital Heart Disease, Genitourinary Malformations, and Developmental Delay

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The interstitial 6p microdeletion syndrome is characterized by dysmorphic facies and structural heart, kidney, brain, and musculoskeletal differences. RREB1 haploinsufficiency and consequent abnormal RAS‐MAPK pathway signaling have been proposed as a driver of the disease phenotype; however, apart from a single case report, the phenotype of ...
Alanna Strong, Caoimhe McKenna, Karen Stals, Antonio Vitobello, Mathilde Renaud, Claudine Rieubland, Michel Guipponi, Christophe Philippe, Paul Vrana, Alisa Gaskell, A. Micheil Innes, Alyssa L. Rippert, Rebecca Ahrens‐Nicklas, Elizabeth Bhoj, Kiersten Keller, Bimal P. Chaudhari, Brandon S. Stone   +16 more
wiley   +1 more source

Resolution of Occlusive Carotid Artery Thrombus Treated with Anticoagulation as Demonstrated on Duplex Ultrasonography. [PDF]

, 2017
BACKGROUND AND PURPOSE: While the majority of cerebral ischemic events due to carotid occlusive disease result from atherosclerotic plaque rupture, intraluminal carotid artery thrombus occasionally occurs in patients without preexisting carotid ...
Liang, John W., Stein, Laura, Weinberger, Jesse   +2 more
core   +2 more sources

Alkaptonuric aortic stenosis [PDF]

European Heart Journal, 2007
A 71-year-old male patient was referred for the evaluation of a high-grade aortic stenosis. His medical history revealed prosthetic hip and joint replacement due to degenerative arthritis at the age of 55. On physical examination, a 2/4 systolic ejection murmur at the right upper sternal border, kyphosis, and a bluish-black discolouration of the sclera
Johannes Möller, Mattias Roser, Philipp Stawowy, Christoph Knosalla, Takeshi Komoda   +4 more
openaire   +3 more sources

Arrhythmic risk in elderly patients candidates to transcatheter aortic valve replacement. predicative role of repolarization temporal dispersion [PDF]

, 2019
Degenerative aortic valve stenosis (AS) is associated to ventricular arrhythmias and sudden cardiac death, as well as mental stress in specific patients. In such a context, substrate, autonomic imbalance as well as repolarization dispersion abnormalities ...
Crapanzano, Davide, DI IORIO, Claudia, Fabietti, Marcella, Magri', Damiano, Mariani, MARCO VALERIO, Mastropietri, Fabiola, Moscucci, Federica, Parrotta, Ilaria, Piccirillo, Gianfranco, Sabatino, Teresa, Salvi, Nicolo', Vespignani, Giulia   +11 more
core   +1 more source

Staging classification of aortic stenosis based on the extent of cardiac damage

European Heart Journal, 2017
Aims In patients with aortic stenosis (AS), risk stratification for aortic valve replacement (AVR) relies mainly on valve-related factors, symptoms and co-morbidities.
P. Généreux, P. Pibarot, B. Redfors, Baylor Michael J. Mack, White Health, R. Makkar, W. Jaber, Cleveland Clinic, L. Svensson, S. Kapadia, E. Tuzcu, V. Thourani, Philippe Ge´ne´reux, B. Redfors, V. Babaliaros, H. Herrmann, W. Szeto, D. Cohen, B. Lindman, T. McAndrew, Maria C. Alu, P. Douglas, R. Hahn, S. Kodali, Craig R. Smith, D. C. Miller, J. Webb, M. Leon   +27 more
semanticscholar   +1 more source

AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Deletions of the 3q26.33q27.2 region appear to correlate with a distinct phenotype, although there are few reported cases. Here, we present seven previously unreported individuals carrying de novo 3q27 deletions (under 5 Mb), which include the AP2M1 (adaptor‐related protein complex 2, mu‐1 subunit) gene and summarize data from 12 previously ...
Russell Gear, Paul Kalitsis, Melissa Glass, Bertrand Isidor, Catherine Vincent‐Delorme, Florence Petit, Judith M. A. Verhagen, Alexander Jorge, Ana Cristina Victorino Krepischi, Ikeoluwa Osei‐Owusu, Eva Martinez, Anne O'Donnell‐Luria, Nicole de Leeuw, Sarah Ruggiero, Ingo Helbig, Francis David I, Natasha J. Brown   +16 more
wiley   +1 more source

Repeatability of fractional flow reserve despite variations in systemic and coronary hemodynamics [PDF]

, 2015
Objectives This study classified and quantified the variation in fractional flow reserve (FFR) due to fluctuations in systemic and coronary hemodynamics during intravenous adenosine infusion.
Berry, C., De Bruyne, B., Fearon, W.F., Gould, K.L., Johnson, D.T., Johnson, N.P., Kirkeeide, R.L., Oldroyd, K.G., Pijls, N.H.J.   +8 more
core   +2 more sources

Myocardial Scar and Mortality in Severe Aortic Stenosis

Circulation, 2018
Background: Aortic valve replacement (AVR) for aortic stenosis is timed primarily on the development of symptoms, but late surgery can result in irreversible myocardial dysfunction and additional risk.
T. Musa, T. Treibel, V. Vassiliou, G. Captur, Anvesha Singh, C. Chin, L. Dobson, S. Pica, M. Loudon, Tamir S. Malley, M. Rigolli, J. R. Foley, P. Bijsterveld, G. Law, M. Dweck, S. Myerson, G. Mccann, S. Prasad, J. Moon, J. Greenwood   +19 more
semanticscholar   +1 more source

Artificial Intelligence Software Changes Rare Disease Testing Strategy in Real Time: An International Case Series Using Face2Gene

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic disorders commonly share features such as developmental delays, cognitive impairment, and behavioral challenges, yet many conditions also present unique dysmorphic features that distinguish them. Performing a thorough medical and family history and a detailed physical exam with attention to dysmorphic features is often the first step ...
Natasha L. Rudy, Adriana Gomes, Tinatin Tkemaladze, Omar Abdul‐Rahman, Drew Cratsenberg, Giulia Pascolini, Giovanni Di Zenzo, Daniele Castiglia, Emily Black, Camerun Washington, Lauren Chad, Cynthia Curry, Miguel Del Campo, Nicole Fleischer, Lynne M. Bird, Anna C. E. Hurst   +15 more
wiley   +1 more source