Results 211 to 220 of about 71,731 (296)

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Evaluation of the Relationship Between Aortic Stiffness and Elasticity and Left Ventricular Functional Parameters in Patients with ANOCA Using CCTA. [PDF]

Int J Gen Med
Sheng A, Zhang L, Zhu D, Hu G, Shi X, Zong Q, Wang P, Wang Z.   +7 more
europepmc   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

The relationship between Brucella infection and aortic stiffness in children. [PDF]

North Clin Istanb
Uygun H, Varan C, Erdem N, Yavuz S, Turgut M.   +4 more
europepmc   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall, Alex M. Williams, Philip J. Millar, Megan L. Lance, Brooke M. Shafer, Conan L. H. Shing, Jordan D. Bird, Christopher R. West, Glen E. Foster   +8 more
wiley   +1 more source

Aortic stiffness after living kidney donation: a systematic review and meta-analysis. [PDF]

BMJ Open
Rodriguez RA, McNeill K, Agharazii M, Bugeja A, Clark EG, Burns KD.   +5 more
europepmc   +1 more source

Translational studies of chronic supplementation with a mitochondria‐targeted antioxidant to improve physical function with ageing

The Journal of Physiology, EarlyView.
Abstract figure legend Chronic oral supplementation with the mitochondria‐targeted antioxidant MitoQ (4 weeks; 250 µm) mitigates age‐related physical dysfunction in old mice, which is associated with reductions in skeletal muscle mitochondria‐specific superoxide and markers of mitochondrial reactive oxygen species (mitoROS)‐related oxidative stress and
Kevin O. Murray, Rachel A. Gioscia‐Ryan, Jaime N. Justice, Jessica R. Santos‐Parker, Nina Z. Bispham, David A. Hutton, Sanna Darvish, Jill Miyamoto‐Ditmon, Zachary S. Clayton, Michel Chonchol, Douglas R. Seals, Matthew J. Rossman   +11 more
wiley   +1 more source

Prevalence of hypertension and cardiovascular risk in patients with gastrointestinal angiodysplasia: the role of aortic stiffness and non-dipper blood pressure patterns; predictive value of novel inflammatory biomarkers. [PDF]

Front Cardiovasc Med
Çakmak A, Kertmen Ö, Çetin Ş.
europepmc   +1 more source

Treating age‐related loss of muscle mass and function: Where should we be focusing?

The Journal of Physiology, EarlyView.
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham, Christopher S. Fry, Avnika Ashok Ruparelia, Shyuan T. Ngo, Séverine Lamon   +4 more
wiley   +1 more source

Beat-to-beat variability of aortic pulse wave velocity: implications for aortic stiffness measurements. [PDF]

J Hypertens
Giudici A, Grillo A, Scalise F, Reesink KD, Delhaas T, Salvi P, Spronck B, Parati G.   +7 more
europepmc   +1 more source