Results 51 to 60 of about 71,731 (296)

Targeting interleukin-1β protects from aortic aneurysms induced by disrupted transforming growth factor β signaling [PDF]

, 2017
Aortic aneurysms are life-threatening conditions with effective treatments mainly limited to emergency surgery or trans-arterial endovascular stent grafts, thus calling for the identification of specific molecular targets.
Bizzotto, Dario, Braghetta, Paola, Bressan, Giorgio M., Carnevale, Daniela, Carnevale, Lorenzo, Carnevale, Raimondo, Casaburo, Manuel, Cifelli, Giuseppe, DA ROS, Francesco, Fardella, Stefania, Iacobucci, Roberta, Lembo, Giuseppe, Perrotta, Marialuisa, Vinciguerra, Iolanda   +13 more
core   +1 more source

Cardiovascular features of possible autonomous cortisol secretion in patients with adrenal incidentalomas [PDF]

, 2018
Background: Low-grade incomplete post-dexamethasone cortisol suppression in patients with adrenal incidentalomas – recently defined as possible autonomous cortisol secretion (pACS) – has been associated with increased cardiovascular events and mortality.
Di Giorgio, Maria Rosaria, D’Aluisio, Denise, Giannetta, Elisa, Isidori, Andrea M., Lenzi, Andrea, Minnetti, Marianna, Morelli, Sergio, Pofi, Riccardo, Rizza, Laura, Sbardella, Emilia, Venneri, Mary Anna, Vestri, Annarita, Vinci, Fabio   +12 more
core   +2 more sources

Cholesterol Efflux: Does It Contribute to Aortic Stiffening?

Journal of Cardiovascular Development and Disease, 2018
Aortic stiffness during cardiac contraction is defined by the rigidity of the aorta and the elastic resistance to deformation. Recent studies suggest that aortic stiffness may be associated with changes in cholesterol efflux in endothelial cells.
Shutan Liao, Craig S. McLachlan
doaj   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

Plasma Metabolome Predicts Aortic Stiffness and Future Risk of Coronary Artery Disease and Mortality After 23 Years of Follow‐Up in the General Population

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Increased aortic stiffness (arteriosclerosis) is associated with early vascular aging independent of age and sex. The underlying mechanisms of early vascular aging remain largely unexplored in the general population.
Filip Ottosson, Gunnar Engström, Marju Orho‐Melander, Olle Melander, Peter M. Nilsson, Madeleine Johansson   +5 more
doaj   +1 more source

Aortic stiffness and microalbuminuria in patients with chronic obstructive pulmonary disease

Egyptian Journal of Chest Disease and Tuberculosis, 2015
Background: Cardiovascular diseases (CVDs) remain a major leading cause of morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD).
Alaa Refaat, Mohamed Abdou, Ali Ismael, Ihab Alhelali   +3 more
doaj   +1 more source

Persistent Vascular Collagen Accumulation Alters Hemodynamic Recovery from Chronic Hypoxia [PDF]

, 2012
Pulmonary arterial hypertension (PAH) is caused by narrowing and stiffening of the pulmonary arteries that increase pulmonary vascular impedance (PVZ). In particular, small arteries narrow and large arteries stiffen. Large pulmonary artery (PA) stiffness
Chesler, Naomi C., Hacker, Timothy A., Molthen, Robert C., Roldan-Alzate, Alejandro, Tabima, Diana M., Wang, Zhijie   +5 more
core   +2 more sources

Aortic stiffness: an age-related prognostic marker?

Journal of Hypertension
Aortic stiffness, a consequence of vascular aging, is an independent predictor of cardiovascular morbidity and mortality. However, the impact of age and sex on its predictive performance remains unclear. We have included 6046 individuals from the population-based Rotterdam study. Survival analyses were performed to investigate
Torino, Claudia, Lu, Zuolin, Tilly, Martijn J., Ikram, M. Kamran, Kavousi, Maryam, Mattace-Raso, Francesco   +5 more
openaire   +2 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

P93 ARE HEMODYNAMIC MEASURES ASSOCIATED WITH FRAILTY IN ELDERLY PATIENTS UNDERGOING TRANSCATHETER AORTIC VALVE IMPLANTATION?

Artery Research, 2017
Background: Aortic valve stenosis (AS) is common in the elderly and is associated with high morbidity and mortality, and leads to functional decline. The aim of this study was to investigate the possible relation between aortic stiffness, AS and frailty ...
Jeannette Goudzwaard, Marjo de Ronde-Tillmans, Nahid El Faquir, Nicolas van Mieghem, Mattie Lenzen, Peter de Jaegere, Francesco Mattace Raso   +6 more
doaj   +1 more source