Results 41 to 50 of about 264,693 (308)

Remote Ischemic Preconditioning Neither Improves Survival nor Reduces Myocardial or Kidney Injury in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) [PDF]

, 2020
BACKGROUND: Peri-interventional myocardial injury occurs frequently during transcatheter aortic valve implantation (TAVI). We assessed the effect of remote ischemic preconditioning (RIPC) on myocardial injury, acute kidney injury (AKIN) and 6-month ...
Flechsig, Mandy, Heidrich, Felix M., Heinzel, Frank R., Ibrahim, Karim, Linke, Axel, Pfluecke, Christian, Quick, Silvio, Ruf, Tobias F., Strasser, Ruth H., Sveric, Krunoslav M., Troeger, Willi, Wiedemann, Stephan, Winzer, Robert, Youssef, Akram, Zhang, Kun   +14 more
core   +1 more source

Quadricuspid aortic valves [PDF]

Clinical Cardiology, 2002
AbstractQuadricuspid aortic valves (QAV) are a rare but well recognized cause of significant aortic regurgitation. The first case was found reported in 1862. Since then there have been 110 reported cases of QAV and we report 4 more. Previously, these were diagnosed at the time of surgery or postmortem examination.
Jonathan, Timperley, Robert, Milner, Andrew J, Marshall, Timothy J, Gilbert   +3 more
openaire   +2 more sources

Modelling mitral valvular dynamics–current trend and future directions [PDF]

, 2017
Dysfunction of mitral valve causes morbidity and premature mortality and remains a leading medical problem worldwide. Computational modelling aims to understand the biomechanics of human mitral valve and could lead to the development of new treatment ...
Berry, Colin, Danton, Mark, Feng, Liuyang, Gao, Hao, Luo, Xiaoyu, Ma, Xingshuan, Qi, Nan   +6 more
core   +1 more source

Aortic Valve Repair [PDF]

Operative Techniques in Thoracic and Cardiovascular Surgery, 2009
Aortic valve replacement remains the gold standard for the treatment of severe aortic valve disease. Techniques for valve repair are emerging as a feasible alternative to valve replacement in selected patients. Advantages include potential reduction in the risks of prosthesis-related complications such as thromboembolism, endocarditis, anticoagulant ...
Boodhwani, Munir, El Khoury, Gebrine
openaire   +1 more source

Impact of frailty on outcomes and readmissions after transcatheter and surgical aortic valve replacement in a national cohortCentral MessagePerspective

JTCVS Open
Objective: We examined the effect of frailty on in-hospital mortality, readmission rates, and hospitalization costs after transcatheter and surgical aortic valve replacement in a population-level cohort.
Travis J. Miles, MD, Christopher T. Ryan, MD, Katie J. Hogan, PhD, Bhavesh S. Sayal, BS, Christopher B. Sylvester, MD, PhD, Todd K. Rosengart, MD, Joseph S. Coselli, MD, Marc R. Moon, MD, Ravi K. Ghanta, MD, Subhasis Chatterjee, MD   +9 more
doaj   +1 more source

C-reactive protein in aortic valve disease [PDF]

, 2006
Aortic Valve Disease, includes a range of disorder severity from mild leaflet thickening without valve obstruction, "aortic sclerosis", to severe calcified aortic stenosis.
Pedro L Sanchez, Anna Maria Mazzone
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Inhibition of MAPK-Erk pathway in vivo attenuates aortic valve disease processes in Emilin1-deficient mouse model [PDF]

, 2017
Aortic valve disease (AVD) is a common condition with a progressive natural history, and presently, there are no pharmacologic treatment strategies. Elastic fiber fragmentation (EFF) is a hallmark of AVD, and increasing evidence implicates developmental ...
Aikawa, Barnette, Basalyga, Bonow, Brown-Augsburger, Brunskill, Brunskill, Chung, Fondard, Franco, Gallegos, Gapski, Ghosh, Gu, Helske, Hinton, Hinton, Holm, Ihn, Iverson, Jensen, Keane, Krenz, Liang, Lindeman, Marshall, Mercer, Mohler, Mozaffarian, Munjal, Nishimura, Nkomo, Perrotta, Poggio, Potter, Rajamannan, Rossebo, Sauls, Schmieder, Schoen, Starcher, Vesely, Wirrig, Wylie-Sears, Xiong, Xiong   +45 more
core   +2 more sources

Raman Microscopy at the Organic–Inorganic Interfaces in Human Calcified Aortic Valves Shows the Co‐Existence of Whitlockite Crystals and Carbonated Hydroxyapatite‐Mineralized Collagen Fibrils

Advanced Functional Materials, EarlyView.
This study advances our understanding of aortic valve stenosis by capturing spatially resolved chemical and structural changes at the nanoscale. The findings highlight the potential of combined Raman and electron microscopy for understanding calcification mechanisms across diverse tissue types.
Robin H. M. Van der Meijden, Carolien T. A Kuster, Amber van Broekhoven, Raphaela Allgayer, Luco Rutten, Rona Roverts, Marta Cerruti, Elena Macías‐Sánchez, Jan Hein Cornel, Salloua el Messaoudi, Anat Akiva, Nico Sommerdijk   +11 more
wiley   +1 more source

Osteoprotegerin inhibits aortic valve calcification and preserves valve function in hypercholesterolemic mice. [PDF]

PLoS ONE, 2013
There are no rigorously confirmed effective medical therapies for calcific aortic stenosis. Hypercholesterolemic Ldlr (-/-) Apob (100/100) mice develop calcific aortic stenosis and valvular cardiomyopathy in old age.
Robert M Weiss, Donald D Lund, Yi Chu, Robert M Brooks, Kathy A Zimmerman, Ramzi El Accaoui, Melissa K Davis, Georges P Hajj, M Bridget Zimmerman, Donald D Heistad   +9 more
doaj   +1 more source