Results 71 to 80 of about 182,660 (317)

Comprehensive assessment of the aortic valve in critically ill patients for the non-cardiologist : part II - chronic aortic regurgitation of the native valve [PDF]

, 2021
: Inadequate diastolic closure of the aortic valve causes aortic regurgitation (AR). Diastolic regurgitation towards the left ventricle (LV) causes LV volume overload, resulting in eccentric LV remodelling.
Al Mafragi, Amar, Malbrain, Manu L.N.G., Manu L.N.G. Malbrain, Guy L. Vermeiren, Vermeiren, Guy L., Walpot, Jeroen, Jeroen Walpot, Amar Al Mafragi   +7 more
core   +1 more source

Contemporary Outcomes in Low‐Gradient Aortic Stenosis Patients Who Underwent Dobutamine Stress Echocardiography

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Detection of flow reserve (FR) by dobutamine stress echocardiography is used for risk stratification in low‐gradient aortic stenosis (AS).
Kimi Sato, Kesavan Sankaramangalam, Krishna Kandregula, Jennifer A. Bullen, Samir R. Kapadia, Amar Krishnaswamy, Stephanie Mick, L. Leonardo Rodriguez, Richard A. Grimm, Venu Menon, Milind Y. Desai, Lars G. Svensson, Brian P. Griffin, Zoran B. Popović   +13 more
doaj   +1 more source

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena, Alessandro De Falco, Deborah Osio, Eleanor Sherlock, Emma Kivuva, Erina Sasaki, Francis H. Sansbury, Nayana Lahiri, Patricia Foley, Sahar Mansour, Shane McKee, Tazeen Ashraf, Nicola Brunetti‐Pierri, Usha Kini   +13 more
wiley   +1 more source

Structure-function relationships in the aortic valve [PDF]

, 2012
PhDGlobally, heart valve dysfunction constitutes a large portion of the cardiovascular disease load, causing high rates of mortality in European and industrialized countries.
Anssari-Benam, Afshin
core  

Percutaneous aortic valve replacement for severe aortic regurgitation in degenerated bioprosthesis: the first valve in valve procedure using the Corevalve Revalving system [PDF]

, 2007
Percutaneous valve replacement for severe aortic stenosis has shown to be an alternative treatment option for non-surgical candidates. We report on the first successful valve in valve procedure in an 80-year-old patient with a severe regurgitation of a ...
Buellesfeld, Lutz, Grube, Eberhard, Wenaweser, Peter, Gerckens, Ulrich   +3 more
core   +1 more source

Myxoma of the aortic valve [PDF]

Interactive CardioVascular and Thoracic Surgery, 2012
Myxomatous tumours can arise from different cardiac structures. They have a special predilection for the left atrium and are an exceedingly uncommon finding in cardiac valves. We report the case of a 28-year old man who presented with a stroke and was found to have a mass arising from his aortic valve.
Angel L, Fernández, Marino, Vega, Mohammad M, El-Diasty, José M, Suárez   +3 more
openaire   +2 more sources

Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco, Alfonso Manuel D'Alessio, Nicola Brunetti‐Pierri   +2 more
wiley   +1 more source

Predicting pressure gradient using artificial intelligence for transcatheter aortic valve replacementCentral MessagePerspective

JTCVS Techniques
Objective: After transcatheter aortic valve replacement, the mean transvalvular pressure gradient indicates the effectiveness of the therapy. The objective is to develop artificial intelligence to predict the post–transcatheter aortic valve replacement ...
Anoushka Dasi, BS, Beom Lee, MS, Venkateshwar Polsani, MD, FACC, FASE, Pradeep Yadav, MD, FACC, Lakshmi Prasad Dasi, PhD, FACC, FAIMBE, Vinod H. Thourani, MD, FACS, FACC   +5 more
doaj   +1 more source

Aortic valve and aneurysms [PDF]

European Heart Journal, 2015
Download the Issue @ a Glance podcast Subscribe to the EHJ Podcast ![Graphic][1] The aorta is the highway in the human circulation, and accordingly any functional or structural change is associated with severe symptoms or even a fatal outcome. The aortic valve is the door to the aorta and it opens up to 3 billion times in a lifetime.
openaire   +2 more sources

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source