Results 211 to 220 of about 20,356 (286)

Extraction of Acoustic Features via Empirical Wavelet Transform to Determine Stenosis Degree of the Left Anterior Descending Artery Based on the Diastolic Heart Sounds of 75 Participants

Annals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
This study proposes a non‐invasive approach for coronary artery disease (CAD) screening by analyzing diastolic heart sounds using an Empirical Wavelet Transform (EWT). Spectral energies e(2) and e(3) were identified as sensitive indicators of left anterior descending artery (LAD) stenosis severity.
Haixia Li, Yafang Zhang, Guofeng Ren, Yun Tian, Yan Chai, Xiaoyan Wang   +5 more
wiley   +1 more source

Impact of prophylactic administration of Levosimendan on short-term and long-term outcome in high-risk patients with severely reduced left-ventricular ejection fraction undergoing cardiac surgery – a retrospective analysis [PDF]

, 2016

core   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

British Journal of Pharmacology, Volume 183, Issue 9, Page 1824-1844, May 2026.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Sofia Laforest, Chelbi Coyle, Ruth Andrew, Natalie Z. M. Homer, Sébastien Bonnet, Sandra Breuils‐Bonnet, Martin Wabitsch, Margaret R. MacLean   +12 more
wiley   +1 more source

Management and Prognosis of Patients With Acute Pericarditis in the Emergency Department: A Retrospective, Single‐Centre Study

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
In this retrospective, single‐centre study conducted in patients with acute pericarditis referred to the Emergency Department, a significant proportion of patients experienced long‐term complications, especially recurrences. Drug doses were compliant with guidelines in a limited number of patients at admission and increased at discharge. Diabetes, COPD,
Lisa Caldera, Chiara Lovati, Alessandra Vecchié, Walter Ageno, Marco Paolo Donadini, Francesco Dentali, Flavio Tangianu, Aldo Bonaventura   +7 more
wiley   +1 more source

Practical Recommendations for Anticoagulation in Patients With Atrial Fibrillation

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Oral anticoagulation (OAC) reduces stroke risk by at least two thirds and mortality by one fourth. The threshold for net clinical benefit of OAC is met when stroke risk exceeds 1%–2% per year. Direct oral anticoagulants (DOACs) are preferred to vitamin K antagonists (VKAs) in most patients, including in the elderly and chronic kidney disease ...
Nicolas Johner, Baris Gencer
wiley   +1 more source

Association Between AI-derived Thoracic Calcium Volume and Aortic Valve Calcification Quantified by Agatston Scoring. [PDF]

In Vivo
Almeida GG, Belde D, Guldimann M, Engelberger S, Euler A, Knöpfli F, Kubik-Huch RA, Thali M, Niemann T.   +8 more
europepmc   +1 more source

T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age‐Related Diseases

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Cardiovascular diseases (CVD) are shaped by a complex interplay with immune mechanisms. In particular, the distinct roles of antigen‐specific T cell mechanisms are emerging as critical determinants across a broad spectrum of conditions, ranging from atherosclerosis, myocardial infarction (MI), heart failure (HF), and myocarditis. Because these
Leon Richter, João Dias‐Ferreira, Gustavo Campos Ramos, DiyaaElDin Ashour   +3 more
wiley   +1 more source

Matrifibrocytes Redefine Cardiac Fibrosis: From Terminal Differentiation to Translational Modulation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 10, May 2026.
ABSTRACT Cardiac fibrosis is increasingly recognized as a dynamic program that resolves into a terminal fibroblast fate, the matrifibrocyte, rather than a persistent myofibroblast state. Lineage‐tracing and single‐cell studies reveal that matrifibrocytes arise from activated myofibroblasts during late scar maturation, lose α‐SMA and proliferative ...
Zhentao Zhang, Hua Zhu
wiley   +1 more source

Sex-Specific Prognostic Value of Aortic Valve Calcium and the Risk for Aortic Stenosis: Multi-Ethnic Study of Atherosclerosis (MESA). [PDF]

Circ Cardiovasc Imaging
Marrero N, Jha K, Grant JK, Razavi AC, Budoff MJ, Shah SJ, Rotter JI, Blumenthal RS, Post WS, Gulati M, Shaw LJ, Thanassoulis G, Blaha MJ, Whelton SP.   +13 more
europepmc   +1 more source

Early Experimental Report of the First 8‐Gene‐Edited Pig‐to‐Rhesus Macaque Cardiac Xenotransplantation in China

Xenotransplantation, Volume 33, Issue 3, May/June 2026.
ABSTRACT Objectives This study aimed to investigate the functional recovery of an 8‐gene‐edited pig heart after orthotopic xenotransplantation, the characteristics of the recipient's immune responses, and the efficacy of postoperative complication management to provide comprehensive experimental evidence for the clinical translation of xenogeneic ...
Xianzhi Wang, Xijie Wu, Ziqiang Dai, Licheng Yan, Jie Yan, Dongsheng He, Shangxuan Li, Zhipeng Ren, Gen Zhang, Guanzheng Cui, Xin Li, Xianhua Li, Yulong Guan, Guangyu Pan, Ik Jin Yun, Wensheng Zhou, Dengke Pan, Dianyuan Li   +17 more
wiley   +1 more source