First Transapical Aortic Valve Replacement at Bagcilar Training and Research Hospital [PDF]
Transcatheter-based aortic valve procedures have undergone a tremendous evolution and have led to great changes in the treatment of aortic valvular disease.
Nihan Kayalar +4 more
doaj +2 more sources
KLF5 Downregulation Links Impaired BNIP3-Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease. [PDF]
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Bian JH +13 more
europepmc +2 more sources
Structure-function relationships in the aortic valve [PDF]
PhDGlobally, heart valve dysfunction constitutes a large portion of the cardiovascular disease load, causing high rates of mortality in European and industrialized countries.
Anssari-Benam, Afshin
core +4 more sources
Transcatheter aortic-valve replacement for inoperable severe aortic stenosis. [PDF]
BACKGROUND: Transcatheter aortic-valve replacement (TAVR) is the recommended therapy for patients with severe aortic stenosis who are not suitable candidates for surgery. The outcomes beyond 1 year in such patients are not known.
Makkar, Raj R +26 more
core +1 more source
Background: Isolated aortic valve disease (IAVD) has traditionally been a disease of elderly, etiology being either senile degeneration of a tricuspid aortic valve or calcification of a bicuspid aortic valve.
Ankit Kumar Sahu +7 more
doaj +1 more source
A case control investigation of the relation between hyperlipidaemia and calcific aortic valve stenosis [PDF]
Objective To investigate the relation of hyperlipidaemia to calcific aortic valve stenosis. Design A case-control study designed to detect a clinically relevant difference in the fasting plasma concentrations of total cholesterol between the groups at ...
Stevenson, R N +3 more
core +1 more source
Correlation Between Aortic Valve Sclerosis and Coronary Artery Disease: A Cross - Sectional Study [PDF]
Introduction: Aortic valve sclerosisis considered as a manifestation of coronary atherosclerosis. Recent studies demonstrated an association between aortic valve sclerosis and obstructive coronary artery disease.
Afsoon Fazlinezhad +3 more
doaj +2 more sources
The myth of aortic valve annulus changes in aortic valve disease
BackgroundThe characteristics of aortic annulus changes in aortic regurgitation (AR) patients are poorly understood, and predictive factors among aortic valve disease are yet to be established.ObjectiveThis study seeks to elucidate the pattern of annular size fluctuations across different cardiac phases in AR patients and to identify predictors for ...
Yanren Peng +6 more
openaire +3 more sources
Transcatheter Aortic Valve Implantation in Dialysis Patients [PDF]
Background/Aims: Transcatheter aortic valve implantation (TAVI) has emerged as a new therapeutic option for high-risk patients. However, dialysis patients were excluded from all previous studies.
Wessely, Matthias +6 more
core +1 more source
Post-stenotic aortic dilatation. [PDF]
Aortic stenosis is the most common valvular heart disease affecting up to 4% of the elderly population. It can be associated with dilatation of the ascending aorta and subsequent dissection.
Jahangiri Marjan +5 more
core +2 more sources

