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Bicuspid aortic valve disease [PDF]
Bicuspid aortic valves are present in 1%–2% of the population, with men being 3 times more commonly affected than women. This disease is more than just anatomic variation and may be associated with other heart and aorta abnormalities as a result of molecular and connective tissue derangements.[1][
Katie L, Losenno, Michael W A, Chu
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Transcatheter versus surgical aortic-valve replacement in high-risk patients. [PDF]
BACKGROUND: The use of transcatheter aortic-valve replacement has been shown to reduce mortality among high-risk patients with aortic stenosis who are not candidates for surgical replacement.
Makkar, Raj R +47 more
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Conditional deletion of RB1 in the Tie2 lineage leads to aortic valve regurgitation. [PDF]
Aortic valve disease is a complex process characterized by valve interstitial cell activation, disruption of the extracellular matrix culminating in valve mineralization occurring over many years.
Marina Freytsis +6 more
doaj +1 more source
Objective: Evaluate the evidence on the abnormalities of the aortic root and heart valves, risk and prognostic factors for heart valve disease and valve replacement surgery in spondyloarthritis.Methods: A systematic literature review was performed using ...
Hye-Sang Park +10 more
doaj +1 more source
Age, Sex, and Valve Phenotype Differences in Fibro‐Calcific Remodeling of Calcified Aortic Valve
Background In calcific aortic valve disease on tricuspid aortic valves (TAVs), men have higher aortic valve calcification and less fibrosis than women. However, little is known in bicuspid aortic valves (BAV).
Martine Voisine +9 more
doaj +1 more source
Objective: This study was conducted to evaluate the prevalence of significant coronary artery disease (CAD) in patients with severe valvular heart disease (VHD) and the association between these two cardiac entities.
Anthony Matta, Nicolas Moussallem
doaj +1 more source
Inhibitory role of Notch1 in calcific aortic valve disease. [PDF]
Aortic valve calcification is the most common form of valvular heart disease, but the mechanisms of calcific aortic valve disease (CAVD) are unknown.
Asha Acharya +8 more
doaj +1 more source
Congenital aortic valve stenosis (AVS) is one of the most common valve anomalies and accounts for 3%–6% of cardiac malformations. As congenital AVS is often progressive, many patients, both children and adults, require transcatheter or surgical ...
Jun Yasuhara +8 more
doaj +1 more source
Coronary Artery Disease in Patients Undergoing Transvalvular Aortic Valve Implantation [PDF]
Coronary artery disease (CAD) is common in patients with severe aortic stenosis. With the advent of transcatheter aortic valve implantation (TAVI) as a therapeutic option, management of CAD in such patients has undergone a revolution.
Edgar Tay +11 more
core +1 more source
Frailty and aortic valve disease [PDF]
Frailty is a common occurrence in elderly persons and is present in approximately half of the patients being screened for transcatheter aortic valve replacement (TAVR) therapy. Accurate assessment of the likelihood of benefit from intervention in the older patient with aortic stenosis is critical with both surgical aortic valve replacement and TAVR now
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